Feature ID Range (original values) IQR (original values) Difference (original values) Fold Change (original values) Weighted proportions difference Weighted proportions fold change Test statistic P-value FDR p-value correction Bonferroni Target description GO biological process Expression values Gene length Unique gene reads Total gene reads RPKM Means Expression values Gene length Unique gene reads Total gene reads RPKM Means ruditapes_lrc29501 3.497 3.497 -3.497 -133.426 -2.50E-06 -132.525 -1.856 0.063 0.605 1 perlucin 6 3.524 653 13 60 3.524 3.524 0.026 653 0 1 0.026 0.026 ruditapes2_lrc6520 3.123 3.123 -3.123 -100.07 -2.23E-06 -99.394 -1.75 0.08 0.703 1 cytochrome c oxidase subunit via polypeptide 1 3.155 547 7 45 3.155 3.155 0.032 547 0 1 0.032 0.032 ruditapes2_c2728 3.215 3.215 -3.215 -67.825 -2.30E-06 -67.367 -1.766 0.077 0.689 1 high mobility group protein b2 /// 0005634 // nucleus /// 0003677 // DNA binding 3.263 717 40 61 3.263 3.263 0.048 717 1 2 0.048 0.048 ruditapes_c2726 543.648 543.648 -543.648 -42.859 -3.89E-04 -42.57 -22.776 8.38E-115 7.19E-112 2.73E-110 rCG56563 [Rattus norvegicus] 556.635 486 696 "7,054" 556.635 556.635 12.988 486 165 366 12.988 12.988 ruditapes_lrc30337 4.715 4.715 -4.715 -40.028 -3.37E-06 -39.758 -2.117 0.034 0.396 1 epididymal secretory protein e1 precursor /// 0043231 // intracellular membrane-bounded organelle /// 0065007 // biological regulation /// 0005488 // binding /// 0005737 // cytoplasm /// 0009987 // cellular process /// 0006869 // lipid transport 4.836 571 13 72 4.836 4.836 0.121 571 0 4 0.121 0.121 ruditapes_lrc19157 15.345 15.345 -15.345 -36.995 -1.10E-05 -36.746 -3.811 1.38E-04 4.11E-03 1 hypothetical protein ZyciCp074 [Zygnema circumcarinatum] 15.771 445 151 183 15.771 15.771 0.426 445 10 11 0.426 0.426 ruditapes_lrc33484 331.339 331.339 -331.339 -28.591 -2.37E-04 -28.398 -17.571 4.21E-69 2.41E-66 1.37E-64 cg12324 protein /// 0005811 // lipid particle /// 0000022 // mitotic spindle elongation 343.348 382 207 "3,420" 343.348 343.348 12.009 382 42 266 12.009 12.009 ruditapes2_c693 5.511 5.511 -5.511 -22.844 -3.94E-06 -22.69 -2.246 0.025 0.309 1 prefoldin subunit 1 /// 0003700 // transcription factor activity /// 0016272 // prefoldin complex /// 0005886 // plasma membrane /// 0007049 // cell cycle /// 0051082 // unfolded protein binding /// 0006457 // protein folding 5.763 752 17 113 5.763 5.763 0.252 752 0 11 0.252 0.252 ruditapes_lrc38794 12.941 12.941 -12.941 -21.896 -9.25E-06 -21.748 -3.435 5.94E-04 0.015 1 ribosomal protein s8 /// 0005811 // lipid particle /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 13.56 362 32 128 13.56 13.56 0.619 362 2 13 0.619 0.619 ruditapes2_c2223 10.559 10.559 -10.559 -21.793 -7.55E-06 -21.646 -3.102 1.92E-03 0.04 1 hypothetical protein GZ9E5_47 [uncultured archaeon GZfos9E5] 11.067 849 218 245 11.067 11.067 0.508 849 24 25 0.508 0.508 ruditapes_lrc35717 3.251 3.251 -3.251 -21.602 -2.33E-06 -21.456 -1.72 0.085 0.734 1 nadh: oxidoreductase subunit /// 0005743 // mitochondrial inner membrane 3.409 765 7 68 3.409 3.409 0.158 765 0 7 0.158 0.158 ruditapes2_lrc5332 23.664 23.664 -23.664 -21.33 -1.69E-05 -21.186 -4.639 3.51E-06 1.49E-04 0.114 atp h+ mitochondrial f0 subunit c (subunit 9) "/// 0015992 // proton transport /// 0015078 // hydrogen ion transmembrane transporter activity /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o)" 24.827 726 9 470 24.827 24.827 1.164 726 1 49 1.164 1.164 ruditapes2_lrc5315 31.27 31.27 -31.27 -20.649 -2.24E-05 -20.51 -5.324 1.02E-07 5.50E-06 3.31E-03 ribosomal protein l32 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003735 // structural constituent of ribosome 32.862 531 10 455 32.862 32.862 1.591 531 1 49 1.591 1.591 ruditapes_lrc32779 6.042 6.042 -6.042 -20.014 -4.32E-06 -19.879 -2.337 0.019 0.258 1 mgc89694 protein /// 0006633 // fatty acid biosynthetic process /// 0000036 // acyl carrier activity /// 0031177 // phosphopantetheine binding /// 0048037 // cofactor binding 6.36 597 0 99 6.36 6.36 0.318 597 0 11 0.318 0.318 ruditapes_c24521 6.348 6.348 -6.348 -16.901 -4.54E-06 -16.787 -2.373 0.018 0.239 1 hypothetical protein CaO19.63 [Candida albicans SC5314] 6.747 432 76 76 6.747 6.747 0.399 432 10 10 0.399 0.399 ruditapes_c9743 94.246 94.246 -94.246 -16.221 -6.74E-05 -16.112 -9.12 7.55E-20 1.27E-17 2.46E-15 zinc finger protein 316 100.438 454 "1,101" "1,189" 100.438 100.438 6.192 454 156 163 6.192 6.192 ruditapes_lrc32217 67.507 67.507 -67.507 -15.19 -4.83E-05 -15.087 -7.685 1.53E-14 1.73E-12 4.98E-10 atp synthase beta subunit "/// 0005524 // ATP binding /// 0043499 // eukaryotic cell surface binding /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0001525 // angiogenesis /// 0005886 // plasma membrane /// 0015986 // ATP synthesis coupled proton transport /// 0006629 // lipid metabolic process /// 0005754 // mitochondrial proton-transporting ATP synthase, catalytic core /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration /// 0046961 // proton-transporting ATPase activity, rotational mechanism /// 0042645 // mitochondrial nucleoid /// 0009986 // cell surface /// 0051453 // regulation of intracellular pH /// 0042288 // MHC class I protein binding /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism" 72.265 899 154 "1,694" 72.265 72.265 4.757 899 23 248 4.757 4.757 ruditapes_c37655 3.252 3.252 -3.252 -14.578 -2.33E-06 -14.48 -1.682 0.093 0.772 1 elastase 2 like 3.492 648 12 59 3.492 3.492 0.24 648 0 9 0.24 0.24 ruditapes2_lrc3698 4.042 4.042 -4.042 -13.76 -2.89E-06 -13.667 -1.867 0.062 0.594 1 lethal neo18 4.359 871 6 99 4.359 4.359 0.317 871 3 16 0.317 0.317 ruditapes_lrc32105 8.525 8.525 -8.525 -12.296 -6.09E-06 -12.213 -2.688 7.19E-03 0.119 1 glutathione s-transferase /// 0005515 // protein binding 9.279 777 4 188 9.279 9.279 0.755 777 0 34 0.755 0.755 ruditapes_c9628 8.165 8.165 -8.165 -10.995 -5.84E-06 -10.921 -2.605 9.18E-03 0.145 1 orf2-encoded protein 8.982 380 89 89 8.982 8.982 0.817 380 18 18 0.817 0.817 ruditapes_lrc34665 7.726 7.726 -7.726 -10.891 -5.52E-06 -10.817 -2.532 0.011 0.171 1 aplp_locmi ame: full=apolipophorins contains: ame: full=apolipophorin-2 ame: full=apolipophorin ii ame: full=apolp-2 contains: ame: full=apolipophorin-1 ame: full=apolipophorin i ame: full=apolp-1 flags: precursor 8.507 861 3 191 8.507 8.507 0.781 861 0 39 0.781 0.781 ruditapes_c3849 3.542 3.542 -3.542 -10.674 -2.53E-06 -10.602 -1.711 0.087 0.742 1 small nuclear ribonucleoprotein polypeptide f /// 0030532 // small nuclear ribonucleoprotein complex /// 0005681 // spliceosomal complex /// 0005515 // protein binding /// 0005654 // nucleoplasm /// 0005829 // cytosol /// 0003723 // RNA binding /// 0000387 // spliceosomal snRNP biogenesis 3.908 471 36 48 3.908 3.908 0.366 471 7 10 0.366 0.366 ruditapes_c32686 7.136 7.136 -7.136 -10.625 -5.10E-06 -10.553 -2.428 0.015 0.213 1 egf-like domain-containing protein 7.878 628 113 129 7.878 7.878 0.741 628 13 27 0.741 0.741 ruditapes_lrc33929 "2,362.23" "2,362.23" "-2,362.23" -10.334 -1.69E-03 -10.265 -44.086 0 0 0 ribosomal protein s27a /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0006414 // translational elongation /// 0046872 // metal ion binding /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005515 // protein binding /// 0005654 // nucleoplasm /// 0030433 // ER-associated protein catabolic process /// 0030528 // transcription regulator activity /// 0016567 // protein ubiquitination /// 0003735 // structural constituent of ribosome /// 0048167 // regulation of synaptic plasticity /// 0022627 // cytosolic small ribosomal subunit /// 0007411 // axon guidance /// 0045941 // positive regulation of transcription /// 0042062 // long-term strengthening of neuromuscular junction "2,615.29" 540 "9,980" "36,825" "2,615.29" "2,615.29" 253.065 540 "1,192" "7,924" 253.065 253.065 ruditapes_lrc32392 5.98 5.98 -5.98 -10.146 -4.28E-06 -10.077 -2.212 0.027 0.33 1 protein 6.634 844 19 146 6.634 6.634 0.654 844 2 32 0.654 0.654 ruditapes_c13771 38.056 38.056 -38.056 -10.08 -2.72E-05 -10.012 -5.577 2.45E-08 1.47E-06 7.98E-04 crumbs homolog 1 isoform ii precursor 42.247 502 450 553 42.247 42.247 4.191 502 103 122 4.191 4.191 ruditapes_lrc35406 5.382 5.382 -5.382 -10.007 -3.85E-06 -9.939 -2.096 0.036 0.411 1 cystatin f 5.979 635 21 99 5.979 5.979 0.597 635 4 22 0.597 0.597 ruditapes_lrc33116 38.803 38.803 -38.803 -9.937 -2.77E-05 -9.87 -5.623 1.88E-08 1.15E-06 6.11E-04 ubiquitin-like protein fubi and ribosomal protein s30 precursor /// 0006414 // translational elongation /// 0005515 // protein binding /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 43.144 568 46 639 43.144 43.144 4.342 568 7 143 4.342 4.342 ruditapes2_c4074 6.987 6.987 -6.987 -9.719 -4.99E-06 -9.653 -2.381 0.017 0.235 1 calcium-binding ef-hand domain protein 7.789 581 25 118 7.789 7.789 0.801 581 2 27 0.801 0.801 ruditapes_c16275 48.131 48.131 -48.131 -9.706 -3.44E-05 -9.641 -6.247 4.17E-10 3.19E-08 1.36E-05 pol-like protein 53.66 496 684 694 53.66 53.66 5.528 496 155 159 5.528 5.528 ruditapes_c16815 3.411 3.411 -3.411 -8.789 -2.44E-06 -8.73 -1.645 0.1 0.806 1 endonuclease reverse transcriptase 3.849 827 83 83 3.849 3.849 0.438 827 21 21 0.438 0.438 ruditapes_lrc32619 4.412 4.412 -4.412 -8.724 -3.15E-06 -8.665 -1.869 0.062 0.593 1 apolipophorin precursor protein 4.983 785 6 102 4.983 4.983 0.571 785 1 26 0.571 0.571 ruditapes2_c7080 5.996 5.996 -5.996 -8.536 -4.29E-06 -8.479 -2.173 0.03 0.358 1 myosin heavy chain /// 0005524 // ATP binding /// 0032440 // 2-alkenal reductase activity /// 0055114 // oxidation reduction /// 0003774 // motor activity /// 0006941 // striated muscle contraction /// 0051015 // actin filament binding /// 0005863 // striated muscle thick filament 6.791 672 25 119 6.791 6.791 0.796 672 7 31 0.796 0.796 ruditapes_lrc33380 150.216 150.216 -150.216 -8.463 -1.07E-04 -8.406 -10.867 1.66E-27 4.22E-25 5.40E-23 40s ribosomal protein s2 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005654 // nucleoplasm /// 0048604 // fibroblast growth factor 3 binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0048602 // fibroblast growth factor 1 binding 170.345 335 54 "1,488" 170.345 170.345 20.129 335 17 391 20.129 20.129 ruditapes_c2465 109.484 109.484 -109.484 -8.458 -7.82E-05 -8.401 -9.277 1.75E-20 3.10E-18 5.71E-16 major surface protein 1a 124.164 484 895 "1,567" 124.164 124.164 14.68 484 182 412 14.68 14.68 ruditapes2_c432 5.763 5.763 -5.763 -8.277 -4.12E-06 -8.221 -2.123 0.034 0.392 1 tnf superfamily ligand tl1a 6.555 784 74 134 6.555 6.555 0.792 784 21 36 0.792 0.792 ruditapes_lrc8074 102.149 102.149 -102.149 -8.118 -7.30E-05 -8.063 -8.915 4.88E-19 7.54E-17 1.59E-14 ribosomal protein s6 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 116.501 "1,138" 253 "3,457" 116.501 116.501 14.351 "1,138" 116 947 14.351 14.351 ruditapes_c15663 33.257 33.257 -33.257 -8.096 -2.38E-05 -8.041 -5.085 3.68E-07 1.82E-05 0.012 pol-like protein 37.943 471 430 466 37.943 37.943 4.687 471 120 128 4.687 4.687 ruditapes2_c4695 103.185 103.185 -103.185 -8.095 -7.37E-05 -8.04 -8.957 3.34E-19 5.32E-17 1.09E-14 ribosomal protein s6 /// 0005811 // lipid particle /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0006955 // immune response 117.729 702 56 "2,155" 117.729 117.729 14.543 702 20 592 14.543 14.543 ruditapes_c28645 9.349 9.349 -9.349 -8.076 -6.68E-06 -8.021 -2.695 7.04E-03 0.117 1 conserved plasmodium protein 10.67 248 69 69 10.67 10.67 1.321 248 19 19 1.321 1.321 ruditapes_lrc35569 48.34 48.34 -48.34 -8.032 -3.45E-05 -7.978 -6.124 9.10E-10 6.76E-08 2.97E-05 atp synthase beta "/// 0005524 // ATP binding /// 0005811 // lipid particle /// 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism" 55.214 705 49 "1,015" 55.214 55.214 6.874 705 21 281 6.874 6.874 ruditapes_c17607 20.911 20.911 -20.911 -7.988 -1.49E-05 -7.934 -4.025 5.69E-05 1.85E-03 1 scavenger receptor class member 2 23.903 438 214 273 23.903 23.903 2.992 438 59 76 2.992 2.992 ruditapes2_lrc3853 18.85 18.85 -18.85 -7.945 -1.35E-05 -7.892 -3.819 1.34E-04 4.00E-03 1 nadh dehydrogenase 1 alpha subcomplex subunit 5 /// 0040007 // growth /// 0002119 // nematode larval development /// 0009792 // embryonic development ending in birth or egg hatching 21.564 610 147 343 21.564 21.564 2.714 610 27 96 2.714 2.714 ruditapes2_c1916 22.639 22.639 -22.639 -7.937 -1.62E-05 -7.884 -4.185 2.86E-05 9.91E-04 0.931 pol-like protein 25.903 724 488 489 25.903 25.903 3.263 724 137 137 3.263 3.263 ruditapes2_c272 305.651 305.651 -305.651 -7.897 -2.18E-04 -7.844 -15.368 2.71E-53 1.25E-50 8.85E-49 e2f-associated phosphoprotein 349.967 797 "7,273" "7,273" 349.967 349.967 44.315 797 "2,043" "2,048" 44.315 44.315 ruditapes_c5274 14.383 14.383 -14.383 -7.872 -1.03E-05 -7.819 -3.332 8.63E-04 0.02 1 orf2-encoded protein 16.476 824 267 354 16.476 16.476 2.093 824 69 100 2.093 2.093 ruditapes_lrc32547 12.271 12.271 -12.271 -7.728 -8.77E-06 -7.676 -3.07 2.14E-03 0.044 1 mitochondrial atp synthase lipid binding protein precursor "/// 0006811 // ion transport /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain" 14.095 955 9 351 14.095 14.095 1.824 955 4 101 1.824 1.824 ruditapes_c2264 185.387 185.387 -185.387 -7.717 -1.33E-04 -7.665 -11.931 8.13E-33 2.48E-30 2.65E-28 peptidyl-prolyl cis-trans isomerase /// 0003755 // peptidyl-prolyl cis-trans isomerase activity /// 0006457 // protein folding 212.987 "1,071" "2,855" "5,948" 212.987 212.987 27.6 "1,071" 480 "1,714" 27.6 27.6 ruditapes_c5489 8.445 8.445 -8.445 -7.698 -6.04E-06 -7.646 -2.546 0.011 0.166 1 glutathione s-transferase /// 0005515 // protein binding 9.706 889 39 225 9.706 9.706 1.261 889 5 65 1.261 1.261 ruditapes_lrc38032 3.487 3.487 -3.487 -7.561 -2.49E-06 -7.51 -1.632 0.103 0.821 1 nucleoside diphosphate kinase b /// 0005488 // binding /// 0009117 // nucleotide metabolic process 4.018 649 0 68 4.018 4.018 0.531 649 0 20 0.531 0.531 ruditapes_lrc35856 3.743 3.743 -3.743 -7.466 -2.68E-06 -7.415 -1.688 0.091 0.767 1 glutathione s-transferase c 4.322 417 2 47 4.322 4.322 0.579 417 0 14 0.579 0.579 ruditapes_c32582 22.82 22.82 -22.82 -7.46 -1.63E-05 -7.409 -4.167 3.09E-05 1.06E-03 1 ribosomal protein l24 /// 0010458 // exit from mitosis /// 0006414 // translational elongation /// 0021554 // optic nerve development /// 0005515 // protein binding /// 0031575 // G1/S transition checkpoint /// 0022625 // cytosolic large ribosomal subunit /// 0031290 // retinal ganglion cell axon guidance /// 0000027 // ribosomal large subunit assembly /// 0060041 // retina development in camera-type eye /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development 26.353 537 0 369 26.353 26.353 3.533 537 0 110 3.533 3.533 ruditapes_lrc33763 "2,109.99" "2,109.99" "-2,109.99" -7.36 -1.51E-03 -7.31 -40.021 0 0 0 ribosomal protein l11 /// 0006414 // translational elongation /// 0006605 // protein targeting /// 0005730 // nucleolus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development /// 0042273 // ribosomal large subunit biogenesis "2,441.77" 436 "1,425" "27,760" "2,441.77" "2,441.77" 331.783 436 226 "8,388" 331.783 331.783 ruditapes2_lrc4338 6.659 6.659 -6.659 -7.325 -4.76E-06 -7.276 -2.245 0.025 0.309 1 ribosomal protein l35a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome /// 0000049 // tRNA binding /// 0042273 // ribosomal large subunit biogenesis 7.711 557 7 112 7.711 7.711 1.053 557 2 34 1.053 1.053 ruditapes_lrc32357 720.748 720.748 -720.748 -7.264 -5.15E-04 -7.215 -23.335 2.05E-120 1.80E-117 6.67E-116 60s ribosomal protein l13a /// 0015934 // large ribosomal subunit /// 0006412 // translation /// 0003735 // structural constituent of ribosome 835.816 714 "8,271" "15,561" 835.816 835.816 115.068 714 "1,204" "4,764" 115.068 115.068 ruditapes2_lrc5256 17.031 17.031 -17.031 -7.198 -1.22E-05 -7.149 -3.581 3.42E-04 9.06E-03 1 ribosomal protein l21 19.778 477 1 246 19.778 19.778 2.748 477 0 76 2.748 2.748 ruditapes_c2038 4.8 4.8 -4.8 -7.088 -3.43E-06 -7.04 -1.897 0.058 0.569 1 mitochondrial ribosomal protein l17 5.588 700 49 102 5.588 5.588 0.788 700 18 32 0.788 0.788 ruditapes_lrc33842 7.331 7.331 -7.331 -6.977 -5.24E-06 -6.929 -2.339 0.019 0.256 1 ribosomal protein s8 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 8.558 717 16 160 8.558 8.558 1.227 717 4 51 1.227 1.227 ruditapes_c2361 41.233 41.233 -41.233 -6.951 -2.95E-05 -6.904 -5.544 2.95E-08 1.76E-06 9.63E-04 hypothetical protein [Eristalis tenax] 48.163 555 199 697 48.163 48.163 6.929 555 65 223 6.929 6.929 ruditapes_c34318 848.434 848.434 -848.434 -6.937 -6.06E-04 -6.89 -25.149 1.51E-139 1.50E-136 4.94E-135 heat shock protein 70 991.347 645 "7,993" "16,673" 991.347 991.347 142.912 645 "1,889" "5,345" 142.912 142.912 ruditapes_lrc35417 4.002 4.002 -4.002 -6.905 -2.86E-06 -6.859 -1.726 0.084 0.729 1 basic transcription factor 3-like 4 4.68 967 0 118 4.68 4.68 0.678 967 0 38 0.678 0.678 ruditapes2_c109 121.441 121.441 -121.441 -6.813 -8.68E-05 -6.767 -9.487 2.39E-21 4.35E-19 7.79E-17 hypothetical protein BRAFLDRAFT_123087 [Branchiostoma floridae] 142.331 672 "2,307" "2,494" 142.331 142.331 20.89 672 658 814 20.89 20.89 ruditapes_lrc20511 140.355 140.355 -140.355 -6.804 -1.00E-04 -6.758 -10.197 2.06E-24 4.53E-22 6.70E-20 26s proteasome regulatory subunit t3 /// 0005524 // ATP binding /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0000502 // proteasome complex /// 0016887 // ATPase activity /// 0005634 // nucleus /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005515 // protein binding /// 0001824 // blastocyst development /// 0005829 // cytosol 164.536 465 "1,674" "1,995" 164.536 164.536 24.181 465 511 652 24.181 24.181 ruditapes_lrc38307 62.866 62.866 -62.866 -6.758 -4.49E-05 -6.712 -6.817 9.31E-12 8.16E-10 3.04E-07 AF339450_1hillarin [Hirudo medicinalis] 73.784 447 731 860 73.784 73.784 10.918 447 141 283 10.918 10.918 ruditapes_c6663 69.2 69.2 -69.2 -6.738 -4.94E-05 -6.693 -7.149 8.76E-13 8.57E-11 2.86E-08 60s ribosomal protein l9 /// 0005622 // intracellular 81.26 429 56 909 81.26 81.26 12.06 429 13 300 12.06 12.06 ruditapes_lrc34142 264.114 264.114 -264.114 -6.659 -1.89E-04 -6.614 -13.942 3.56E-44 1.40E-41 1.16E-39 mitochondrial atp synthase gamma-subunit "/// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism" 310.786 732 "3,449" "5,932" 310.786 310.786 46.672 732 954 "1,981" 46.672 46.672 ruditapes_lrc34485 4.26 4.26 -4.26 -6.586 -3.04E-06 -6.541 -1.767 0.077 0.688 1 cg15828 cg15828- partial 5.022 588 1 77 5.022 5.022 0.763 588 0 26 0.763 0.763 ruditapes_c7529 29.289 29.289 -29.289 -6.559 -2.09E-05 -6.515 -4.631 3.63E-06 1.54E-04 0.118 histone 1 /// 0005634 // nucleus /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0000786 // nucleosome 34.558 455 410 410 34.558 34.558 5.268 455 139 139 5.268 5.268 ruditapes_lrc33106 68.869 68.869 -68.869 -6.512 -4.92E-05 -6.468 -7.094 1.31E-12 1.23E-10 4.26E-08 ribosomal protein l18a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 81.363 617 14 "1,309" 81.363 81.363 12.494 617 1 447 12.494 12.494 ruditapes2_c1875 4.848 4.848 -4.848 -6.469 -3.46E-06 -6.425 -1.88 0.06 0.584 1 cytochrome p450 /// 0016491 // oxidoreductase activity /// 0008152 // metabolic process 5.735 428 55 64 5.735 5.735 0.886 428 20 22 0.886 0.886 ruditapes_s37764 3.68 3.68 -3.68 -6.41 -2.63E-06 -6.366 -1.636 0.102 0.816 1 beta-tubulin /// 0000166 // nucleotide binding /// 0007017 // microtubule-based process 4.36 431 0 49 4.36 4.36 0.68 431 0 17 0.68 0.68 ruditapes2_lrc5091 11.5 11.5 -11.5 -6.344 -8.22E-06 -6.301 -2.886 3.90E-03 0.072 1 nadh dehydrogenase 1 alpha subcomplex subunit 6 "/// 0003954 // NADH dehydrogenase activity /// 0006120 // mitochondrial electron transport, NADH to ubiquinone /// 0005747 // mitochondrial respiratory chain complex I" 13.651 545 5 194 13.651 13.651 2.152 545 1 68 2.152 2.152 ruditapes_lrc32649 3.876 3.876 -3.876 -6.274 -2.77E-06 -6.232 -1.673 0.094 0.78 1 receptor of activated kinase c 1 /// 0019903 // protein phosphatase binding /// 0005886 // plasma membrane /// 0043025 // cell soma /// 0005737 // cytoplasm /// 0005102 // receptor binding 4.611 657 3 79 4.611 4.611 0.735 657 0 28 0.735 0.735 ruditapes_c21703 27.477 27.477 -27.477 -6.248 -1.96E-05 -6.206 -4.45 8.57E-06 3.36E-04 0.279 PREDICTED: similar to CG13990-PA [Rattus norvegicus] 32.713 415 354 354 32.713 32.713 5.236 415 126 126 5.236 5.236 ruditapes_s38677 16.237 16.237 -16.237 -6.203 -1.16E-05 -6.161 -3.417 6.33E-04 0.015 1 ribosomal protein l32 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 19.358 315 10 159 19.358 19.358 3.121 315 4 57 3.121 3.121 ruditapes2_lrc4165 97.157 97.157 -97.157 -6.187 -6.94E-05 -6.145 -8.355 6.54E-17 8.95E-15 2.13E-12 ribosomal protein l8 /// 0044424 // intracellular part 115.888 871 50 "2,632" 115.888 115.888 18.731 871 19 946 18.731 18.731 ruditapes_lrc31388 7.477 7.477 -7.477 -6.065 -5.34E-06 -6.024 -2.31 0.021 0.271 1 conserved hypothetical protein [Culex quinquefasciatus] 8.953 514 119 120 8.953 8.953 1.476 514 44 44 1.476 1.476 ruditapes2_c1713 32.617 32.617 -32.617 -6.051 -2.33E-05 -6.01 -4.823 1.42E-06 6.44E-05 0.046 loc794406 protein /// 0005634 // nucleus /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0000786 // nucleosome 39.075 900 917 917 39.075 39.075 6.458 900 337 337 6.458 6.458 ruditapes2_c3229 184.949 184.949 -184.949 -5.991 -1.32E-04 -5.951 -11.465 1.99E-30 5.64E-28 6.48E-26 cyclophilin-type peptidyl-prolyl cis-trans isomerase /// 0003755 // peptidyl-prolyl cis-trans isomerase activity /// 0006457 // protein folding 222.006 "1,042" 443 "6,032" 222.006 222.006 37.057 "1,042" 184 "2,239" 37.057 37.057 ruditapes2_lrc4701 "1,876.82" "1,876.82" "-1,876.82" -5.979 -1.34E-03 -5.938 -36.532 4.37E-292 6.20E-289 1.43E-287 tubulin beta-2c chain "2,253.78" 465 "4,529" "27,327" "2,253.78" "2,253.78" 376.959 465 "2,631" "10,164" 376.959 376.959 ruditapes_lrc27132 4.282 4.282 -4.282 -5.93 -3.06E-06 -5.89 -1.741 0.082 0.713 1 heat shock protein 22 isoform 2 5.15 417 54 56 5.15 5.15 0.868 417 17 21 0.868 0.868 ruditapes_lrc31148 448.53 448.53 -448.53 -5.835 -3.20E-04 -5.795 -17.773 1.17E-70 6.79E-68 3.80E-66 beta 2c /// 0005488 // binding /// 0009987 // cellular process 541.3 812 "9,552" "11,461" 541.3 541.3 92.77 812 "2,903" "4,368" 92.77 92.77 ruditapes2_lrc4170 778.619 778.619 -778.619 -5.825 -5.56E-04 -5.785 -23.412 3.37E-121 3.05E-118 1.10E-116 beta 2c /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0042267 // natural killer cell mediated cytotoxicity /// 0005874 // microtubule /// 0006928 // cell motion /// 0051082 // unfolded protein binding /// 0042288 // MHC class I protein binding /// 0007018 // microtubule-based movement 940.004 785 "5,631" "19,241" 940.004 940.004 161.385 785 "2,121" "7,346" 161.385 161.385 ruditapes_lrc26425 3.882 3.882 -3.882 -5.698 -2.77E-06 -5.66 -1.646 0.1 0.805 1 ependymin related protein-1 precursor 4.708 334 8 41 4.708 4.708 0.826 334 2 16 0.826 0.826 ruditapes_c4257 8.436 8.436 -8.436 -5.69 -6.03E-06 -5.652 -2.426 0.015 0.214 1 copine family protein 10.235 326 6 87 10.235 10.235 1.799 326 1 34 1.799 1.799 ruditapes_lrc35961 30.679 30.679 -30.679 -5.628 -2.19E-05 -5.59 -4.617 3.90E-06 1.64E-04 0.127 ribosomal protein l7a /// 0042254 // ribosome biogenesis /// 0005840 // ribosome 37.307 588 21 572 37.307 37.307 6.628 588 17 226 6.628 6.628 ruditapes_c21056 "26,019.75" "26,019.75" "-26,019.75" -5.583 -0.019 -5.545 -135.601 0 0 0 cytochrome c subunit ii /// 0006810 // transport /// 0005507 // copper ion binding /// 0004129 // cytochrome-c oxidase activity /// 0020037 // heme binding /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane /// 0009055 // electron carrier activity /// 0022904 // respiratory electron transport chain "31,697.62" 193 "132,517" "159,519" "31,697.62" "31,697.62" "5,677.87" 193 "56,385" "63,542" "5,677.87" "5,677.87" ruditapes_c3371 15.412 15.412 -15.412 -5.537 -1.10E-05 -5.499 -3.262 1.11E-03 0.025 1 protein /// 0003755 // peptidyl-prolyl cis-trans isomerase activity /// 0006457 // protein folding 18.809 995 49 488 18.809 18.809 3.397 995 17 196 3.397 3.397 ruditapes_c3095 49.181 49.181 -49.181 -5.537 -3.51E-05 -5.5 -5.828 5.62E-09 3.75E-07 1.83E-04 SclB protein [Capnocytophaga gingivalis ATCC 33624] 60.022 945 "1,470" "1,479" 60.022 60.022 10.84 945 581 594 10.84 10.84 ruditapes_lrc38397 4.932 4.932 -4.932 -5.478 -3.52E-06 -5.441 -1.842 0.066 0.617 1 DEC-3 [Lymnaea stagnalis] 6.033 642 68 101 6.033 6.033 1.101 642 29 41 1.101 1.101 ruditapes2_c3534 396.16 396.16 -396.16 -5.417 -2.83E-04 -5.381 -16.473 5.79E-61 2.95E-58 1.89E-56 phosphatase 2a inhibitor i2pp2a /// 0044424 // intracellular part 485.844 "1,083" "3,368" "13,720" 485.844 485.844 89.684 "1,083" "1,222" "5,632" 89.684 89.684 ruditapes_c6682 11.498 11.498 -11.498 -5.416 -8.21E-06 -5.38 -2.806 5.02E-03 0.088 1 predicted protein [Nematostella vectensis] 14.102 669 120 246 14.102 14.102 2.604 669 70 101 2.604 2.604 ruditapes_lrc34445 3.972 3.972 -3.972 -5.408 -2.84E-06 -5.371 -1.649 0.099 0.802 1 nucleoside diphosphate kinase variant 1 /// 0005488 // binding /// 0009117 // nucleotide metabolic process 4.874 842 42 107 4.874 4.874 0.901 842 3 44 0.901 0.901 ruditapes2_lrc4584 23.069 23.069 -23.069 -5.355 -1.65E-05 -5.319 -3.966 7.32E-05 2.33E-03 1 predicted protein [Nematostella vectensis] 28.367 726 106 537 28.367 28.367 5.297 726 53 223 5.297 5.297 ruditapes_c32846 9.842 9.842 -9.842 -5.329 -7.03E-06 -5.293 -2.588 9.66E-03 0.151 1 beta-ig-h3 fasciclin 12.116 402 9 127 12.116 12.116 2.274 402 8 53 2.274 2.274 ruditapes_c2307 28.068 28.068 -28.068 -5.319 -2.01E-05 -5.283 -4.368 1.25E-05 4.72E-04 0.408 small nuclear ribonucleoprotein sm d3 /// 0007417 // central nervous system development /// 0030532 // small nuclear ribonucleoprotein complex /// 0005681 // spliceosomal complex /// 0048542 // lymph gland development /// 0005730 // nucleolus /// 0005515 // protein binding /// 0005654 // nucleoplasm /// 0003676 // nucleic acid binding /// 0007422 // peripheral nervous system development /// 0005829 // cytosol /// 0030182 // neuron differentiation /// 0007517 // muscle organ development /// 0000387 // spliceosomal snRNP biogenesis /// 0007052 // mitotic spindle organization 34.566 "1,510" 978 "1,361" 34.566 34.566 6.499 "1,510" 398 569 6.499 6.499 ruditapes_c36522 4.899 4.899 -4.899 -5.295 -3.50E-06 -5.259 -1.823 0.068 0.634 1 mitochondrial ribosomal protein l11 /// 0005622 // intracellular 6.039 635 51 100 6.039 6.039 1.141 635 24 42 1.141 1.141 ruditapes_lrc32142 12.334 12.334 -12.334 -5.284 -8.81E-06 -5.249 -2.892 3.83E-03 0.071 1 transport protein sec61 subunit gamma /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity /// 0006886 // intracellular protein transport /// 0030176 // integral to endoplasmic reticulum membrane 15.213 605 39 240 15.213 15.213 2.879 605 14 101 2.879 2.879 ruditapes_c9736 28.551 28.551 -28.551 -5.177 -2.04E-05 -5.142 -4.382 1.18E-05 4.46E-04 0.383 ependymin related protein 1 35.386 815 752 752 35.386 35.386 6.835 815 323 323 6.835 6.835 ruditapes_c4080 14.738 14.738 -14.738 -5.164 -1.05E-05 -5.129 -3.147 1.65E-03 0.035 1 hypothetical protein NEMVEDRAFT_v1g145479 [Nematostella vectensis] 18.277 726 136 346 18.277 18.277 3.539 726 76 149 3.539 3.539 ruditapes_lrc38595 95.643 95.643 -95.643 -5.121 -6.83E-05 -5.086 -8.003 1.22E-15 1.49E-13 3.98E-11 ribosomal protein s16 /// 0044424 // intracellular part 118.853 454 5 "1,407" 118.853 118.853 23.21 454 0 611 23.21 23.21 ruditapes_lrc21475 19.313 19.313 -19.313 -5.109 -1.38E-05 -5.074 -3.594 3.25E-04 8.70E-03 1 ribosomal protein s4 /// 0003729 // mRNA binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0030528 // transcription regulator activity /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0003735 // structural constituent of ribosome 24.013 543 16 340 24.013 24.013 4.7 543 8 148 4.7 4.7 ruditapes2_c1764 23.882 23.882 -23.882 -5.094 -1.71E-05 -5.06 -3.994 6.49E-05 2.09E-03 1 mitochondrial ribosomal protein s15 "/// 0044403 // symbiosis, encompassing mutualism through parasitism" 29.715 "1,017" 788 788 29.715 29.715 5.833 "1,017" 343 344 5.833 5.833 ruditapes_c24070 7.393 7.393 -7.393 -5.093 -5.28E-06 -5.059 -2.222 0.026 0.324 1 protein 9.199 296 71 71 9.199 9.199 1.806 296 31 31 1.806 1.806 ruditapes2_c16 42.442 42.442 -42.442 -5.068 -3.03E-05 -5.034 -5.319 1.04E-07 5.63E-06 3.40E-03 cg8844 /// 0055114 // oxidation reduction /// 0005739 // mitochondrion /// 0016020 // membrane /// 0016491 // oxidoreductase activity 52.876 800 785 "1,103" 52.876 52.876 10.434 800 266 484 10.434 10.434 ruditapes2_lrc5593 7.263 7.263 -7.263 -5.021 -5.19E-06 -4.988 -2.196 0.028 0.342 1 nadh dehydrogenase 1 alpha subcomplex subunit 5 /// 0040007 // growth /// 0002119 // nematode larval development /// 0009792 // embryonic development ending in birth or egg hatching 9.069 592 71 140 9.069 9.069 1.806 592 26 62 1.806 1.806 ruditapes_lrc33070 14.958 14.958 -14.958 -4.993 -1.07E-05 -4.959 -3.148 1.64E-03 0.035 1 predicted protein [Nematostella vectensis] 18.704 732 57 357 18.704 18.704 3.746 732 36 159 3.746 3.746 ruditapes_lrc24298 49.156 49.156 -49.156 -4.929 -3.51E-05 -4.896 -5.691 1.26E-08 7.99E-07 4.11E-04 large subunit ribosomal protein 27a /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 61.666 528 90 849 61.666 61.666 12.51 528 56 383 12.51 12.51 ruditapes_c7895 10.163 10.163 -10.163 -4.914 -7.26E-06 -4.881 -2.586 9.71E-03 0.151 1 coiled-coil domain containing 86 12.76 538 179 179 12.76 12.76 2.596 538 81 81 2.596 2.596 ruditapes2_lrc4160 14.37 14.37 -14.37 -4.908 -1.03E-05 -4.874 -3.074 2.11E-03 0.043 1 glutathione s-transferase /// 0005515 // protein binding 18.047 680 3 320 18.047 18.047 3.677 680 1 145 3.677 3.677 ruditapes2_c439 222.058 222.058 -222.058 -4.905 -1.59E-04 -4.872 -12.084 1.29E-33 4.04E-31 4.20E-29 dynein light chain cytoplasmic "/// 0005868 // cytoplasmic dynein complex /// 0007290 // spermatid nucleus elongation /// 0042623 // ATPase activity, coupled /// 0007476 // imaginal disc-derived wing morphogenesis /// 0016459 // myosin complex /// 0051017 // actin filament bundle formation /// 0005634 // nucleus /// 0043186 // P granule /// 0008407 // bristle morphogenesis /// 0005886 // plasma membrane /// 0008039 // synaptic target recognition /// 0007291 // sperm individualization /// 0005829 // cytosol /// 0005874 // microtubule /// 0008092 // cytoskeletal protein binding /// 0003777 // microtubule motor activity /// 0045505 // dynein intermediate chain binding /// 0042803 // protein homodimerization activity /// 0007018 // microtubule-based movement" 278.929 897 "6,393" "6,524" 278.929 278.929 56.871 897 "2,714" "2,958" 56.871 56.871 ruditapes_c21651 5.343 5.343 -5.343 -4.868 -3.82E-06 -4.835 -1.871 0.061 0.591 1 apical endosomal glycoprotein 6.724 462 80 81 6.724 6.724 1.381 462 37 37 1.381 1.381 ruditapes2_lrc4716 5.681 5.681 -5.681 -4.861 -4.06E-06 -4.828 -1.929 0.054 0.542 1 loc567151 protein /// 0032403 // protein complex binding /// 0043234 // protein complex /// 0006412 // translation /// 0005829 // cytosol /// 0005792 // microsome 7.153 504 9 94 7.153 7.153 1.471 504 2 43 1.471 1.471 ruditapes2_lrc4862 48.044 48.044 -48.044 -4.835 -3.43E-05 -4.802 -5.603 2.11E-08 1.28E-06 6.88E-04 aplp_locmi ame: full=apolipophorins contains: ame: full=apolipophorin-2 ame: full=apolipophorin ii ame: full=apolp-2 contains: ame: full=apolipophorin-1 ame: full=apolipophorin i ame: full=apolp-1 flags: precursor 60.573 925 62 "1,461" 60.573 60.573 12.529 925 33 672 12.529 12.529 ruditapes_c10084 149.146 149.146 -149.146 -4.741 -1.07E-04 -4.709 -9.83 8.41E-23 1.67E-20 2.74E-18 camp response element-binding protein 5 189.009 671 "3,295" "3,307" 189.009 189.009 39.863 671 "1,517" "1,551" 39.863 39.863 ruditapes_lrc38271 47.939 47.939 -47.939 -4.734 -3.42E-05 -4.702 -5.571 2.54E-08 1.52E-06 8.28E-04 cg15828 cg15828- partial 60.779 501 73 794 60.779 60.779 12.84 501 37 373 12.84 12.84 ruditapes2_lrc4908 9.65 9.65 -9.65 -4.726 -6.89E-06 -4.694 -2.498 0.012 0.182 1 cyclophilin-type peptidyl-prolyl cis-trans isomerase 12.24 "1,012" 33 323 12.24 12.24 2.59 "1,012" 15 152 2.59 2.59 ruditapes_c27614 8.698 8.698 -8.698 -4.726 -6.21E-06 -4.694 -2.372 0.018 0.239 1 scavenger receptor cysteine-rich protein 11.033 650 145 187 11.033 11.033 2.335 650 81 88 2.335 2.335 ruditapes2_lrc4792 381.089 381.089 -381.089 -4.723 -2.72E-04 -4.691 -15.7 1.52E-55 7.20E-53 4.97E-51 translationally controlled tumor protein 483.453 683 176 "8,610" 483.453 483.453 102.363 683 264 "4,054" 102.363 102.363 ruditapes_lrc34670 259.37 259.37 -259.37 -4.705 -1.85E-04 -4.673 -12.94 2.68E-38 9.38E-36 8.72E-34 ribosomal protein s6 /// 0005811 // lipid particle /// 0005840 // ribosome /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0003735 // structural constituent of ribosome 329.383 586 121 "5,033" 329.383 329.383 70.013 586 80 "2,379" 70.013 70.013 ruditapes2_lrc3426 5.11 5.11 -5.11 -4.704 -3.65E-06 -4.672 -1.816 0.069 0.641 1 mitochondrial ubiquinol-cytochrome c reductase hinge protein "/// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c /// 0005750 // mitochondrial respiratory chain complex III /// 0008121 // ubiquinol-cytochrome-c reductase activity" 6.49 650 14 110 6.49 6.49 1.38 650 11 52 1.38 1.38 ruditapes2_c5101 6.857 6.857 -6.857 -4.7 -4.90E-06 -4.668 -2.103 0.035 0.406 1 heavy polypeptide non-muscle /// 0007409 // axonogenesis /// 0006810 // transport /// 0003774 // motor activity /// 0032559 // adenyl ribonucleotide binding /// 0015629 // actin cytoskeleton /// 0043005 // neuron projection /// 0030239 // myofibril assembly /// 0003779 // actin binding /// 0021591 // ventricular system development /// 0051649 // establishment of localization in cell /// 0005737 // cytoplasm /// 0055013 // cardiac muscle cell development /// 0030902 // hindbrain development /// 0007507 // heart development /// 0044430 // cytoskeletal part /// 0016477 // cell migration 8.71 819 18 186 8.71 8.71 1.853 819 10 88 1.853 1.853 ruditapes_c12803 556.925 556.925 -556.925 -4.654 -3.98E-04 -4.623 -18.918 8.25E-80 5.17E-77 2.69E-75 alpha 3d /// 0005929 // cilium /// 0005932 // microtubule basal body /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0005515 // protein binding /// 0043234 // protein complex /// 0005874 // microtubule /// 0007018 // microtubule-based movement 709.327 847 "10,830" "15,666" 709.327 709.327 152.402 847 "6,079" "7,485" 152.402 152.402 ruditapes_c38754 4.281 4.281 -4.281 -4.619 -3.06E-06 -4.587 -1.655 0.098 0.796 1 endo- -beta-glucanase "/// 0000272 // polysaccharide catabolic process /// 0016798 // hydrolase activity, acting on glycosyl bonds" 5.464 379 35 54 5.464 5.464 1.183 379 17 26 1.183 1.183 ruditapes_lrc34608 30.599 30.599 -30.599 -4.608 -2.19E-05 -4.577 -4.423 9.72E-06 3.77E-04 0.317 s-adenosylhomocysteine hydrolase /// 0004013 // adenosylhomocysteinase activity /// 0005488 // binding /// 0006730 // one-carbon metabolic process 39.08 789 194 804 39.08 39.08 8.481 789 32 388 8.481 8.481 ruditapes2_c3356 48.996 48.996 -48.996 -4.606 -3.50E-05 -4.575 -5.597 2.19E-08 1.32E-06 7.13E-04 protein /// 0005515 // protein binding 62.583 891 151 "1,454" 62.583 62.583 13.588 891 74 702 13.588 13.588 ruditapes2_c3354 26.883 26.883 -26.883 -4.597 -1.92E-05 -4.566 -4.144 3.42E-05 1.16E-03 1 tubulin polymerization-promoting protein family member 3 34.357 "1,066" 164 955 34.357 34.357 7.474 "1,066" 82 462 7.474 7.474 ruditapes_lrc34369 5.734 5.734 -5.734 -4.593 -4.09E-06 -4.562 -1.913 0.056 0.556 1 ribosomal protein l27 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 7.331 497 0 95 7.331 7.331 1.596 497 0 46 1.596 1.596 ruditapes_lrc33987 10.927 10.927 -10.927 -4.554 -7.80E-06 -4.523 -2.636 8.39E-03 0.135 1 alpha 3 type vi collagen isoform 1 precursor 14.001 819 109 299 14.001 14.001 3.074 819 22 146 3.074 3.074 ruditapes_lrc32391 14.51 14.51 -14.51 -4.532 -1.04E-05 -4.502 -3.034 2.41E-03 0.048 1 ribosomal protein s11 /// 0005840 // ribosome /// 0019843 // rRNA binding /// 0006412 // translation /// 0003735 // structural constituent of ribosome 18.617 550 0 267 18.617 18.617 4.108 550 0 131 4.108 4.108 ruditapes2_lrc4749 4.887 4.887 -4.887 -4.527 -3.49E-06 -4.496 -1.76 0.078 0.693 1 ribosomal protein s5 /// 0006414 // translational elongation /// 0006413 // translational initiation /// 0003729 // mRNA binding /// 0006450 // regulation of translational fidelity /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 6.273 697 0 114 6.273 6.273 1.386 697 0 56 1.386 1.386 ruditapes2_c41 5.214 5.214 -5.214 -4.488 -3.72E-06 -4.458 -1.815 0.07 0.643 1 selenium-dependent glutathione peroxidase /// 0006749 // glutathione metabolic process /// 0005625 // soluble fraction /// 0042744 // hydrogen peroxide catabolic process /// 0008430 // selenium binding /// 0004602 // glutathione peroxidase activity /// 0043295 // glutathione binding 6.709 "1,269" 219 222 6.709 6.709 1.495 "1,269" 87 110 1.495 1.495 ruditapes_c26041 8.811 8.811 -8.811 -4.487 -6.29E-06 -4.456 -2.359 0.018 0.246 1 trna (guanine-n7-)-methyltransferase /// 0006400 // tRNA modification /// 0008176 // tRNA (guanine-N7-)-methyltransferase activity /// 0009792 // embryonic development ending in birth or egg hatching 11.338 389 115 115 11.338 11.338 2.527 389 57 57 2.527 2.527 ruditapes_lrc32467 109.425 109.425 -109.425 -4.478 -7.81E-05 -4.447 -8.309 9.69E-17 1.30E-14 3.16E-12 ribosomal protein l11 /// 0006414 // translational elongation /// 0006605 // protein targeting /// 0005730 // nucleolus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development /// 0042273 // ribosomal large subunit biogenesis 140.891 610 112 "2,241" 140.891 140.891 31.466 610 31 "1,113" 31.466 31.466 ruditapes_c17941 29.201 29.201 -29.201 -4.467 -2.09E-05 -4.437 -4.289 1.79E-05 6.48E-04 0.584 l _3 /// 0044238 // primary metabolic process /// 0034960 // cellular biopolymer metabolic process 37.624 475 465 466 37.624 37.624 8.423 475 232 232 8.423 8.423 ruditapes_s39701 47.05 47.05 -47.05 -4.448 -3.36E-05 -4.418 -5.439 5.35E-08 3.01E-06 1.75E-03 eukaryotic translation initiation factor 60.697 393 342 622 60.697 60.697 13.647 393 151 311 13.647 13.647 ruditapes_c670 10.72 10.72 -10.72 -4.425 -7.65E-06 -4.395 -2.593 9.51E-03 0.149 1 calmodulin /// 0019904 // protein domain specific binding /// 0031997 // N-terminal myristoylation domain binding /// 0005886 // plasma membrane /// 0005876 // spindle microtubule /// 0031432 // titin binding /// 0000922 // spindle pole /// 0005829 // cytosol /// 0051592 // response to calcium ion /// 0007049 // cell cycle /// 0005813 // centrosome /// 0007186 // G-protein coupled receptor protein signaling pathway /// 0005509 // calcium ion binding /// 0032465 // regulation of cytokinesis 13.85 "1,091" 93 394 13.85 13.85 3.13 "1,091" 38 198 3.13 3.13 ruditapes_c35878 6.132 6.132 -6.132 -4.419 -4.38E-06 -4.389 -1.961 0.05 0.513 1 proteasome ( macropain) 26s 1 /// 0005634 // nucleus /// 0005488 // binding /// 0030163 // protein catabolic process /// 0051439 // regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0016787 // hydrolase activity 7.926 750 55 155 7.926 7.926 1.794 750 19 78 1.794 1.794 ruditapes_c8518 11.743 11.743 -11.743 -4.386 -8.38E-06 -4.356 -2.708 6.77E-03 0.113 1 glucosidase 2 subunit beta 15.212 716 278 284 15.212 15.212 3.468 716 139 144 3.468 3.468 ruditapes_c32371 4.379 4.379 -4.379 -4.371 -3.13E-06 -4.341 -1.652 0.098 0.799 1 eukaryotic translation initiation factor subunit h 5.678 "1,155" 10 171 5.678 5.678 1.299 "1,155" 5 87 1.299 1.299 ruditapes2_c568 7.655 7.655 -7.655 -4.349 -5.46E-06 -4.319 -2.182 0.029 0.352 1 protein 9.941 679 20 176 9.941 9.941 2.286 679 5 90 2.286 2.286 ruditapes_lrc32238 17.615 17.615 -17.615 -4.337 -1.26E-05 -4.308 -3.308 9.41E-04 0.022 1 ependymin precursor 22.893 722 157 431 22.893 22.893 5.279 722 44 221 5.279 5.279 ruditapes_lrc35225 33.228 33.228 -33.228 -4.337 -2.37E-05 -4.308 -4.543 5.54E-06 2.25E-04 0.181 ribosomal protein l4 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 43.186 698 63 786 43.186 43.186 9.957 698 32 403 9.957 9.957 ruditapes_lrc35995 5.764 5.764 -5.764 -4.289 -4.12E-06 -4.26 -1.887 0.059 0.58 1 nadh dehydrogenase 1 beta 8kda 7.517 551 11 108 7.517 7.517 1.753 551 12 56 1.753 1.753 ruditapes2_lrc5221 42.642 42.642 -42.642 -4.28 -3.04E-05 -4.251 -5.13 2.91E-07 1.46E-05 9.47E-03 ppia protein /// 0003755 // peptidyl-prolyl cis-trans isomerase activity /// 0006457 // protein folding 55.644 703 116 "1,020" 55.644 55.644 13.002 703 46 530 13.002 13.002 ruditapes_lrc34973 14.828 14.828 -14.828 -4.269 -1.06E-05 -4.24 -3.023 2.50E-03 0.05 1 elongation factor 1-beta /// 0006414 // translational elongation /// 0005853 // eukaryotic translation elongation factor 1 complex /// 0003746 // translation elongation factor activity 19.364 711 13 359 19.364 19.364 4.536 711 7 187 4.536 4.536 ruditapes_c2045 15.097 15.097 -15.097 -4.267 -1.08E-05 -4.238 -3.05 2.29E-03 0.046 1 aldehyde dehydrogenase 1a3 /// 0002072 // optic cup morphogenesis involved in camera-type eye development /// 0043065 // positive regulation of apoptosis /// 0042573 // retinoic acid metabolic process /// 0021768 // nucleus accumbens development /// 0048048 // embryonic eye morphogenesis /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity /// 0060166 // olfactory pit development 19.718 918 365 472 19.718 19.718 4.621 918 177 246 4.621 4.621 ruditapes_lrc33849 21.263 21.263 -21.263 -4.248 -1.52E-05 -4.219 -3.615 3.00E-04 8.11E-03 1 h+ transporting f1 atp synthase epsilon subunit "/// 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism" 27.809 382 9 277 27.809 27.809 6.546 382 8 145 6.546 6.546 ruditapes_lrc33941 8.997 8.997 -8.997 -4.245 -6.42E-06 -4.217 -2.351 0.019 0.25 1 ribosomal protein l27 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 11.769 479 8 147 11.769 11.769 2.772 479 4 77 2.772 2.772 ruditapes_lrc25342 551.992 551.992 -551.992 -4.235 -3.94E-04 -4.206 -18.41 1.11E-75 6.83E-73 3.62E-71 ribosomal protein s7 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 722.647 287 396 "5,408" 722.647 722.647 170.655 287 183 "2,840" 170.655 170.655 ruditapes2_c1683 104.272 104.272 -104.272 -4.23 -7.44E-05 -4.201 -7.998 1.27E-15 1.55E-13 4.13E-11 thermoresistant gluconokinase family protein 136.555 453 "1,401" "1,613" 136.555 136.555 32.283 453 744 848 32.283 32.283 ruditapes_c3528 21.015 21.015 -21.015 -4.229 -1.50E-05 -4.2 -3.59 3.31E-04 8.80E-03 1 cytochrome c oxidase subunit viic 27.523 673 268 483 27.523 27.523 6.509 673 77 254 6.509 6.509 ruditapes_lrc34074 474.893 474.893 -474.893 -4.226 -3.39E-04 -4.198 -17.067 2.65E-65 1.44E-62 8.64E-61 ribosomal protein l18a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 622.09 624 783 "10,122" 622.09 622.09 147.197 624 315 "5,326" 147.197 147.197 ruditapes_lrc33417 78.424 78.424 -78.424 -4.177 -5.60E-05 -4.149 -6.914 4.72E-12 4.26E-10 1.54E-07 guanine nucleotide binding protein (g protein) beta polypeptide 2-like 1 /// 0019903 // protein phosphatase binding /// 0005886 // plasma membrane /// 0043025 // cell soma /// 0005737 // cytoplasm /// 0005102 // receptor binding /// 0007165 // signal transduction 103.109 "1,034" 330 "2,780" 103.109 103.109 24.684 "1,034" 136 "1,480" 24.684 24.684 ruditapes_lrc32519 25.416 25.416 -25.416 -4.154 -1.81E-05 -4.126 -3.93 8.49E-05 2.65E-03 1 translationally controlled tumor protein 33.473 747 8 652 33.473 33.473 8.057 747 17 349 8.057 8.057 ruditapes_c18690 17.769 17.769 -17.769 -4.118 -1.27E-05 -4.09 -3.279 1.04E-03 0.024 1 PREDICTED: similar to AGAP007723-PA [Tribolium castaneum] 23.468 469 287 287 23.468 23.468 5.7 469 155 155 5.7 5.7 ruditapes2_c251 9.094 9.094 -9.094 -4.113 -6.49E-06 -4.085 -2.345 0.019 0.253 1 mitochondrial ribosomal protein s21 /// 0005763 // mitochondrial small ribosomal subunit /// 0006412 // translation /// 0005743 // mitochondrial inner membrane /// 0003735 // structural constituent of ribosome 12.015 549 91 172 12.015 12.015 2.921 549 55 93 2.921 2.921 ruditapes2_c3244 24.587 24.587 -24.587 -4.098 -1.76E-05 -4.07 -3.852 1.17E-04 3.56E-03 1 calmodulin /// 0005524 // ATP binding /// 0005516 // calmodulin binding /// 0005513 // detection of calcium ion /// 0030424 // axon /// 0051383 // kinetochore organization /// 0007268 // synaptic transmission /// 0008049 // male courtship behavior /// 0032036 // myosin heavy chain binding /// 0051533 // positive regulation of NFAT protein import into nucleus /// 0006468 // protein amino acid phosphorylation /// 0048786 // presynaptic active zone /// 0045211 // postsynaptic membrane /// 0051489 // regulation of filopodium assembly /// 0000922 // spindle pole /// 0016060 // metarhodopsin inactivation /// 0005737 // cytoplasm /// 0016062 // adaptation of rhodopsin mediated signaling /// 0007528 // neuromuscular junction development /// 0005954 // calcium- and calmodulin-dependent protein kinase complex /// 0007616 // long-term memory /// 0004683 // calmodulin-dependent protein kinase activity /// 0005509 // calcium ion binding /// 0016061 // regulation of light-activated channel activity /// 0016028 // rhabdomere /// 0030425 // dendrite /// 0007052 // mitotic spindle organization 32.523 691 79 586 32.523 32.523 7.937 691 63 318 7.937 7.937 ruditapes_c18722 4.749 4.749 -4.749 -4.096 -3.39E-06 -4.069 -1.693 0.091 0.762 1 cyclin b3 /// 0005634 // nucleus 6.282 641 105 105 6.282 6.282 1.534 641 57 57 1.534 1.534 ruditapes2_lrc7137 17.115 17.115 -17.115 -4.095 -1.22E-05 -4.068 -3.213 1.31E-03 0.029 1 eukaryotic translation initiation factor subunit h /// 0032403 // protein complex binding /// 0043234 // protein complex /// 0006412 // translation /// 0003743 // translation initiation factor activity /// 0005829 // cytosol /// 0005792 // microsome 22.645 315 15 186 22.645 22.645 5.53 315 8 101 5.53 5.53 ruditapes_c11009 8.254 8.254 -8.254 -4.073 -5.89E-06 -4.046 -2.228 0.026 0.321 1 aconitase family member (aco-2) /// 0007275 // multicellular organismal development /// 0000003 // reproduction 10.939 610 174 174 10.939 10.939 2.686 610 93 95 2.686 2.686 ruditapes_s38260 6.535 6.535 -6.535 -4.064 -4.66E-06 -4.037 -1.981 0.048 0.496 1 ribosomal protein l35a /// 0009987 // cellular process /// 0005622 // intracellular 8.668 469 2 106 8.668 8.668 2.133 469 4 58 2.133 2.133 ruditapes_lrc37105 23.707 23.707 -23.707 -4.045 -1.69E-05 -4.017 -3.769 1.64E-04 4.79E-03 1 ribosomal protein l4 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 31.494 660 83 542 31.494 31.494 7.787 660 52 298 7.787 7.787 ruditapes_c37744 13.68 13.68 -13.68 -4.043 -9.76E-06 -4.016 -2.863 4.20E-03 0.076 1 beta-tubulin 18.176 422 50 200 18.176 18.176 4.495 422 40 110 4.495 4.495 ruditapes_lrc32539 52.868 52.868 -52.868 -4.017 -3.77E-05 -3.99 -5.618 1.93E-08 1.18E-06 6.29E-04 ribosomal protein l38 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development 70.392 310 16 569 70.392 70.392 17.524 310 6 315 17.524 17.524 ruditapes_lrc33003 27.95 27.95 -27.95 -3.999 -2.00E-05 -3.972 -4.08 4.50E-05 1.49E-03 1 mitochondrial atp synthase lipid binding protein precursor "/// 0015992 // proton transport /// 0015078 // hydrogen ion transmembrane transporter activity /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o)" 37.268 744 37 723 37.268 37.268 9.318 744 44 402 9.318 9.318 ruditapes2_lrc5217 159.029 159.029 -159.029 -3.994 -1.14E-04 -3.967 -9.73 2.26E-22 4.36E-20 7.36E-18 ribosomal protein l4 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 212.142 790 774 "4,370" 212.142 212.142 53.113 790 373 "2,433" 53.113 53.113 ruditapes_c16242 5.423 5.423 -5.423 -3.987 -3.87E-06 -3.961 -1.796 0.073 0.661 1 inhibitor of apoptosis isoform a /// 0007166 // cell surface receptor linked signal transduction /// 0050829 // defense response to Gram-negative bacterium /// 0006916 // anti-apoptosis /// 0005515 // protein binding /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade /// 0019730 // antimicrobial humoral response /// 0005829 // cytosol /// 0008270 // zinc ion binding /// 0007423 // sensory organ development 7.239 551 66 104 7.239 7.239 1.815 551 40 58 1.815 1.815 ruditapes2_c2791 37.37 37.37 -37.37 -3.961 -2.67E-05 -3.934 -4.705 2.53E-06 1.10E-04 0.083 hypothetical protein Kpol_464p3 [Vanderwaltozyma polyspora DSM 70294] 49.992 593 449 773 49.992 49.992 12.622 593 239 434 12.622 12.622 ruditapes2_c361 "1,348.36" "1,348.36" "-1,348.36" -3.95 -9.62E-04 -3.923 -28.258 1.23E-175 1.39E-172 4.02E-171 ribosomal protein l19 /// 0006414 // translational elongation /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome "1,805.49" 661 "6,113" "31,119" "1,805.49" "1,805.49" 457.13 661 "4,984" "17,521" 457.13 457.13 ruditapes2_c3799 6.716 6.716 -6.716 -3.937 -4.79E-06 -3.91 -1.991 0.046 0.489 1 triosephosphate isomerase /// 0004807 // triose-phosphate isomerase activity /// 0006633 // fatty acid biosynthetic process /// 0048046 // apoplast /// 0005739 // mitochondrion /// 0006096 // glycolysis /// 0005886 // plasma membrane /// 0009570 // chloroplast stroma /// 0005829 // cytosol /// 0006098 // pentose-phosphate shunt /// 0006094 // gluconeogenesis /// 0046686 // response to cadmium ion /// 0009651 // response to salt stress /// 0005618 // cell wall 9.003 558 69 131 9.003 9.003 2.287 558 40 74 2.287 2.287 ruditapes2_lrc4897 11.05 11.05 -11.05 -3.929 -7.89E-06 -3.903 -2.553 0.011 0.163 1 hydrogen-transporting atp g- /// 0005811 // lipid particle 14.823 608 22 235 14.823 14.823 3.773 608 8 133 3.773 3.773 ruditapes2_c1356 114.688 114.688 -114.688 -3.929 -8.19E-05 -3.902 -8.225 1.95E-16 2.54E-14 6.35E-12 tropomyosin 153.844 "2,429" 831 "9,744" 153.844 153.844 39.156 "2,429" 420 "5,515" 39.156 39.156 ruditapes2_c183 13.489 13.489 -13.489 -3.916 -9.63E-06 -3.889 -2.818 4.83E-03 0.085 1 calreticulin /// 0005783 // endoplasmic reticulum /// 0005509 // calcium ion binding /// 0051082 // unfolded protein binding /// 0006457 // protein folding 18.116 "1,122" 44 530 18.116 18.116 4.627 "1,122" 15 301 4.627 4.627 ruditapes2_c2031 14.036 14.036 -14.036 -3.91 -1.00E-05 -3.883 -2.873 4.06E-03 0.074 1 peroxiredoxin 6 /// 0044444 // cytoplasmic part /// 0043231 // intracellular membrane-bounded organelle /// 0045454 // cell redox homeostasis /// 0016491 // oxidoreductase activity /// 0016787 // hydrolase activity /// 0016209 // antioxidant activity /// 0016042 // lipid catabolic process 18.86 547 218 269 18.86 18.86 4.824 547 109 153 4.824 4.824 ruditapes_lrc38059 38.713 38.713 -38.713 -3.903 -2.76E-05 -3.877 -4.77 1.84E-06 8.25E-05 0.06 atp h+ mitochondrial f1 gamma polypeptide 1 /// 0015992 // proton transport /// 0015078 // hydrogen ion transmembrane transporter activity /// 0016787 // hydrolase activity /// 0006754 // ATP biosynthetic process 52.047 560 96 760 52.047 52.047 13.335 560 84 433 13.335 13.335 ruditapes_c16419 21.035 21.035 -21.035 -3.902 -1.50E-05 -3.876 -3.516 4.39E-04 0.011 1 plasminogen /// 0005576 // extracellular region /// 0048518 // positive regulation of biological process /// 0005515 // protein binding /// 0051917 // regulation of fibrinolysis /// 0048513 // organ development /// 0008233 // peptidase activity /// 0050794 // regulation of cellular process 28.284 640 455 472 28.284 28.284 7.249 640 244 269 7.249 7.249 ruditapes_c3273 9.022 9.022 -9.022 -3.898 -6.44E-06 -3.872 -2.302 0.021 0.275 1 eukaryotic translation initiation factor 3 subunit 7 /// 0006413 // translational initiation /// 0003743 // translation initiation factor activity /// 0005737 // cytoplasm 12.135 493 83 156 12.135 12.135 3.113 493 49 89 3.113 3.113 ruditapes_c16708 22.732 22.732 -22.732 -3.894 -1.62E-05 -3.868 -3.653 2.59E-04 7.18E-03 1 radial spokehead-like 3 30.587 494 394 394 30.587 30.587 7.855 494 225 225 7.855 7.855 ruditapes2_lrc3676 5.413 5.413 -5.413 -3.877 -3.86E-06 -3.851 -1.78 0.075 0.676 1 predicted protein [Nematostella vectensis] 7.295 715 29 136 7.295 7.295 1.881 715 16 78 1.881 1.881 ruditapes_lrc35836 9.188 9.188 -9.188 -3.874 -6.56E-06 -3.848 -2.319 0.02 0.267 1 cytosolic malate dehydrogenase /// 0030060 // L-malate dehydrogenase activity /// 0055114 // oxidation reduction /// 0019674 // NAD metabolic process /// 0006107 // oxaloacetate metabolic process /// 0006108 // malate metabolic process /// 0006099 // tricarboxylic acid cycle /// 0006096 // glycolysis /// 0051287 // NAD or NADH binding /// 0005625 // soluble fraction /// 0005829 // cytosol /// 0004470 // malic enzyme activity 12.386 836 11 270 12.386 12.386 3.197 836 3 155 3.197 3.197 ruditapes_c27963 9.525 9.525 -9.525 -3.872 -6.80E-06 -3.846 -2.361 0.018 0.245 1 surface protein /// 0007126 // meiosis /// 0003774 // motor activity /// 0007064 // mitotic sister chromatid cohesion /// 0005816 // spindle pole body /// 0000742 // karyogamy during conjugation with cellular fusion /// 0007017 // microtubule-based process 12.841 884 272 296 12.841 12.841 3.316 884 158 170 3.316 3.316 ruditapes2_c2188 40.058 40.058 -40.058 -3.871 -2.86E-05 -3.844 -4.841 1.29E-06 5.92E-05 0.042 leydig cell tumor 10 kda protein homolog 54.013 524 738 738 54.013 54.013 13.955 524 424 424 13.955 13.955 ruditapes_c1966 72.247 72.247 -72.247 -3.867 -5.16E-05 -3.841 -6.499 8.07E-11 6.55E-09 2.63E-06 ribosomal protein l19 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 97.447 464 232 "1,179" 97.447 97.447 25.2 464 273 678 25.2 25.2 ruditapes2_c372 99.213 99.213 -99.213 -3.864 -7.08E-05 -3.838 -7.615 2.64E-14 2.90E-12 8.61E-10 thioredoxin (allergen cop c 2) 133.85 "1,424" "1,614" "4,970" 133.85 133.85 34.637 "1,424" 997 "2,860" 34.637 34.637 ruditapes_lrc33622 48.056 48.056 -48.056 -3.862 -3.43E-05 -3.836 -5.299 1.17E-07 6.23E-06 3.81E-03 ribosomal protein l11 /// 0006414 // translational elongation /// 0006605 // protein targeting /// 0005730 // nucleolus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0042273 // ribosomal large subunit biogenesis 64.849 343 16 580 64.849 64.849 16.793 343 9 334 16.793 16.793 ruditapes2_lrc5368 12.165 12.165 -12.165 -3.858 -8.68E-06 -3.832 -2.665 7.70E-03 0.126 1 ribosomal protein l35a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0042273 // ribosomal large subunit biogenesis 16.422 397 0 170 16.422 16.422 4.257 397 0 98 4.257 4.257 ruditapes_c23934 23.277 23.277 -23.277 -3.854 -1.66E-05 -3.828 -3.686 2.28E-04 6.40E-03 1 dead (asp-glu-ala-asp) box polypeptide 49 /// 0003676 // nucleic acid binding /// 0000166 // nucleotide binding /// 0004386 // helicase activity 31.434 499 409 409 31.434 31.434 8.156 499 236 236 8.156 8.156 ruditapes_c12514 6.072 6.072 -6.072 -3.851 -4.33E-06 -3.825 -1.882 0.06 0.583 1 ubiquitin-conjugating enzyme e2 a /// 0006511 // ubiquitin-dependent protein catabolic process /// 0000785 // chromatin /// 0051246 // regulation of protein metabolic process /// 0001701 // in utero embryonic development /// 0043687 // post-translational protein modification /// 0006301 // postreplication repair /// 0005515 // protein binding /// 0004842 // ubiquitin-protein ligase activity 8.201 664 142 142 8.201 8.201 2.13 664 82 82 2.13 2.13 ruditapes_c5084 69.685 69.685 -69.685 -3.85 -4.97E-05 -3.824 -6.375 1.83E-10 1.44E-08 5.97E-06 beta-tubulin /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0005874 // microtubule /// 0007018 // microtubule-based movement 94.136 "1,223" 106 "3,002" 94.136 94.136 24.451 "1,223" 181 "1,734" 24.451 24.451 ruditapes_c1195 34.013 34.013 -34.013 -3.846 -2.43E-05 -3.82 -4.453 8.48E-06 3.34E-04 0.277 vacuolar atp synthase 16 kda proteolipid subunit "/// 0005794 // Golgi apparatus /// 0005774 // vacuolar membrane /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0005515 // protein binding /// 0005764 // lysosome /// 0046961 // proton-transporting ATPase activity, rotational mechanism /// 0016021 // integral to membrane /// 0033179 // proton-transporting V-type ATPase, V0 domain /// 0060059 // embryonic retina morphogenesis in camera-type eye /// 0044419 // interspecies interaction between organisms" 45.964 "1,078" "1,116" "1,292" 45.964 45.964 11.95 "1,078" 517 747 11.95 11.95 ruditapes_s36828 164.788 164.788 -164.788 -3.84 -1.18E-04 -3.814 -9.797 1.17E-22 2.26E-20 3.80E-18 ribosomal protein l9 222.813 384 362 "2,231" 222.813 222.813 58.025 384 89 "1,292" 58.025 58.025 ruditapes_lrc33424 14.579 14.579 -14.579 -3.831 -1.04E-05 -3.805 -2.912 3.60E-03 0.067 1 ribosomal protein s11 /// 0005840 // ribosome /// 0019843 // rRNA binding /// 0006412 // translation /// 0003735 // structural constituent of ribosome 19.729 519 0 267 19.729 19.729 5.15 519 0 155 5.15 5.15 ruditapes2_c575 17.886 17.886 -17.886 -3.825 -1.28E-05 -3.799 -3.224 1.27E-03 0.028 1 cg8844 /// 0055114 // oxidation reduction /// 0005739 // mitochondrion /// 0016020 // membrane /// 0016491 // oxidoreductase activity 24.219 768 332 485 24.219 24.219 6.332 768 153 282 6.332 6.332 ruditapes_lrc34765 5.686 5.686 -5.686 -3.805 -4.06E-06 -3.779 -1.815 0.07 0.643 1 atpase mitochondrial 7.714 706 19 142 7.714 7.714 2.027 706 14 83 2.027 2.027 ruditapes_c11333 6.867 6.867 -6.867 -3.801 -4.90E-06 -3.775 -1.994 0.046 0.487 1 ataxin-2-like protein 9.318 605 57 147 9.318 9.318 2.451 605 51 86 2.451 2.451 ruditapes_c14886 4.797 4.797 -4.797 -3.799 -3.42E-06 -3.773 -1.666 0.096 0.786 1 homolog 1 ( coli) /// 0031167 // rRNA methylation /// 0008168 // methyltransferase activity 6.511 483 82 82 6.511 6.511 1.714 483 48 48 1.714 1.714 ruditapes_c9031 22.363 22.363 -22.363 -3.784 -1.60E-05 -3.759 -3.594 3.26E-04 8.71E-03 1 calmodulin /// 0032440 // 2-alkenal reductase activity /// 0055114 // oxidation reduction /// 0019861 // flagellum /// 0005515 // protein binding /// 0005509 // calcium ion binding 30.395 511 349 405 30.395 30.395 8.032 511 219 238 8.032 8.032 ruditapes_lrc36041 5.66 5.66 -5.66 -3.78 -4.04E-06 -3.755 -1.807 0.071 0.649 1 ribosomal protein l4 /// 0006414 // translational elongation /// 0030529 // ribonucleoprotein complex /// 0005515 // protein binding /// 0005829 // cytosol 7.696 593 0 119 7.696 7.696 2.036 593 0 70 2.036 2.036 ruditapes_c33242 17.117 17.117 -17.117 -3.777 -1.22E-05 -3.751 -3.142 1.68E-03 0.036 1 type alpha 1 23.282 649 41 394 23.282 23.282 6.165 649 53 232 6.165 6.165 ruditapes_c16504 6.848 6.848 -6.848 -3.775 -4.89E-06 -3.749 -1.987 0.047 0.491 1 sphingomyelin phosphodiesterase 9.317 531 129 129 9.317 9.317 2.468 531 74 76 2.468 2.468 ruditapes_c24998 42.487 42.487 -42.487 -3.762 -3.03E-05 -3.736 -4.945 7.62E-07 3.58E-05 0.025 arylsulfatase [Haliotis discus discus] 57.871 389 497 587 57.871 57.871 15.384 389 252 347 15.384 15.384 ruditapes2_c3715 20.766 20.766 -20.766 -3.758 -1.48E-05 -3.733 -3.456 5.48E-04 0.014 1 calmodulin /// 0005524 // ATP binding /// 0005516 // calmodulin binding /// 0006091 // generation of precursor metabolites and energy /// 0019904 // protein domain specific binding /// 0031997 // N-terminal myristoylation domain binding /// 0006468 // protein amino acid phosphorylation /// 0004687 // myosin light chain kinase activity /// 0005886 // plasma membrane /// 0005876 // spindle microtubule /// 0031432 // titin binding /// 0000922 // spindle pole /// 0005829 // cytosol /// 0051592 // response to calcium ion /// 0007049 // cell cycle /// 0005813 // centrosome /// 0008218 // bioluminescence /// 0000287 // magnesium ion binding /// 0007186 // G-protein coupled receptor protein signaling pathway /// 0017022 // myosin binding /// 0005509 // calcium ion binding /// 0018298 // protein-chromophore linkage /// 0032465 // regulation of cytokinesis /// 0043388 // positive regulation of DNA binding 28.295 717 254 529 28.295 28.295 7.528 717 124 313 7.528 7.528 ruditapes2_c1323 24.943 24.943 -24.943 -3.754 -1.78E-05 -3.729 -3.786 1.53E-04 4.50E-03 1 calreticulin /// 0005783 // endoplasmic reticulum /// 0005509 // calcium ion binding /// 0051082 // unfolded protein binding /// 0006457 // protein folding 34 "1,093" 94 969 34 34 9.057 "1,093" 33 574 9.057 9.057 ruditapes_lrc35190 8.486 8.486 -8.486 -3.736 -6.06E-06 -3.711 -2.205 0.027 0.335 1 fungal metazoan origin like protein variant 2 /// 0016021 // integral to membrane 11.588 695 195 210 11.588 11.588 3.102 695 108 125 3.102 3.102 ruditapes_c19539 4.752 4.752 -4.752 -3.733 -3.39E-06 -3.708 -1.65 0.099 0.801 1 g patch domain containing 4 6.492 833 141 141 6.492 6.492 1.739 833 84 84 1.739 1.739 ruditapes2_lrc4839 72.323 72.323 -72.323 -3.716 -5.16E-05 -3.691 -6.429 1.29E-10 1.03E-08 4.20E-06 ribosomal protein l6 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 98.947 662 106 "1,708" 98.947 98.947 26.624 662 63 "1,022" 26.624 26.624 ruditapes2_c3037 17.496 17.496 -17.496 -3.713 -1.25E-05 -3.688 -3.161 1.57E-03 0.034 1 atp:adp antiporter /// 0005200 // structural constituent of cytoskeleton /// 0005773 // vacuole /// 0005856 // cytoskeleton /// 0048767 // root hair elongation /// 0007010 // cytoskeleton organization /// 0005730 // nucleolus /// 0005488 // binding /// 0005886 // plasma membrane /// 0015865 // purine nucleotide transport /// 0005471 // ATP:ADP antiporter activity /// 0009507 // chloroplast /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane /// 0005618 // cell wall 23.944 583 31 364 23.944 23.944 6.449 583 33 218 6.449 6.449 ruditapes_c3430 22.867 22.867 -22.867 -3.703 -1.63E-05 -3.678 -3.611 3.05E-04 8.25E-03 1 hypothetical protein [Paramecium tetraurelia strain d4-2] 31.326 475 242 388 31.326 31.326 8.459 475 172 233 8.459 8.459 ruditapes_lrc33495 696.345 696.345 -696.345 -3.702 -4.97E-04 -3.677 -19.93 2.26E-88 1.61E-85 7.38E-84 aplp_locmi ame: full=apolipophorins contains: ame: full=apolipophorin-2 ame: full=apolipophorin ii ame: full=apolp-2 contains: ame: full=apolipophorin-1 ame: full=apolipophorin i ame: full=apolp-1 flags: precursor 954.064 963 881 "23,957" 954.064 954.064 257.719 963 597 "14,391" 257.719 257.719 ruditapes_c13884 13.513 13.513 -13.513 -3.679 -9.64E-06 -3.654 -2.77 5.60E-03 0.096 1 l _3 18.557 465 224 225 18.557 18.557 5.044 465 136 136 5.044 5.044 ruditapes2_lrc4195 18.709 18.709 -18.709 -3.67 -1.34E-05 -3.645 -3.257 1.12E-03 0.025 1 dynein light chain /// 0030286 // dynein complex /// 0005737 // cytoplasm /// 0005874 // microtubule /// 0003777 // microtubule motor activity /// 0007017 // microtubule-based process 25.717 598 27 401 25.717 25.717 7.008 598 19 243 7.008 7.008 ruditapes_c3961 20.31 20.31 -20.31 -3.661 -1.45E-05 -3.637 -3.392 6.95E-04 0.017 1 h+ transporting f1 atp synthase epsilon subunit "/// 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism" 27.942 409 22 298 27.942 27.942 7.632 409 12 181 7.632 7.632 ruditapes2_c649 5.736 5.736 -5.736 -3.644 -4.09E-06 -3.619 -1.8 0.072 0.657 1 proline-rich transmembrane protein 1 7.905 "1,892" 133 390 7.905 7.905 2.169 "1,892" 86 238 2.169 2.169 ruditapes_c22159 9.46 9.46 -9.46 -3.619 -6.75E-06 -3.595 -2.307 0.021 0.273 1 coiled-coil domain containing 96 13.072 487 166 166 13.072 13.072 3.612 487 102 102 3.612 3.612 ruditapes_lrc22398 17.291 17.291 -17.291 -3.618 -1.23E-05 -3.594 -3.118 1.82E-03 0.038 1 60s ribosomal protein l40 "/// 0005524 // ATP binding /// 0005634 // nucleus /// 0019079 // viral genome replication /// 0006508 // proteolysis /// 0003968 // RNA-directed RNA polymerase activity /// 0033897 // ribonuclease T2 activity /// 0005515 // protein binding /// 0019082 // viral protein processing /// 0005840 // ribosome /// 0006410 // transcription, RNA-dependent /// 0030528 // transcription regulator activity /// 0016021 // integral to membrane /// 0006412 // translation /// 0016567 // protein ubiquitination /// 0003723 // RNA binding /// 0004252 // serine-type endopeptidase activity /// 0003735 // structural constituent of ribosome /// 0045941 // positive regulation of transcription /// 0004386 // helicase activity" 23.896 329 114 205 23.896 23.896 6.605 329 40 126 6.605 6.605 ruditapes_lrc32511 13.825 13.825 -13.825 -3.6 -9.86E-06 -3.575 -2.784 5.37E-03 0.093 1 atp synthase subunit b 19.143 587 74 293 19.143 19.143 5.318 587 47 181 5.318 5.318 ruditapes_lrc31742 249.713 249.713 -249.713 -3.584 -1.78E-04 -3.56 -11.817 3.20E-32 9.65E-30 1.04E-27 basic transcription factor 3-like 4 346.344 935 "1,041" "8,444" 346.344 346.344 96.632 935 162 "5,239" 96.632 96.632 ruditapes2_c368 42.927 42.927 -42.927 -3.577 -3.06E-05 -3.553 -4.896 9.77E-07 4.53E-05 0.032 cyclophilin-type peptidyl-prolyl cis-trans isomerase /// 0003755 // peptidyl-prolyl cis-trans isomerase activity /// 0006457 // protein folding 59.584 "1,053" 230 "1,636" 59.584 59.584 16.656 "1,053" 118 "1,017" 16.656 16.656 ruditapes_lrc16474 24.408 24.408 -24.408 -3.564 -1.74E-05 -3.54 -3.688 2.26E-04 6.37E-03 1 h3 family 3b /// 0005634 // nucleus /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0000786 // nucleosome 33.928 980 29 867 33.928 33.928 9.52 980 11 541 9.52 9.52 ruditapes2_lrc5464 6.879 6.879 -6.879 -3.558 -4.91E-06 -3.534 -1.957 0.05 0.516 1 ribosomal protein s13 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0003729 // mRNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0033119 // negative regulation of RNA splicing 9.568 481 1 120 9.568 9.568 2.689 481 0 75 2.689 2.689 ruditapes_c9915 9.222 9.222 -9.222 -3.518 -6.58E-06 -3.494 -2.258 0.024 0.302 1 serologically defined colon cancer antigen 1 12.885 631 212 212 12.885 12.885 3.662 631 134 134 3.662 3.662 ruditapes_lrc33154 19.844 19.844 -19.844 -3.51 -1.42E-05 -3.486 -3.309 9.35E-04 0.022 1 ribosomal protein l8 /// 0006414 // translational elongation /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0003735 // structural constituent of ribosome 27.75 890 42 644 27.75 27.75 7.906 890 15 408 7.906 7.906 ruditapes2_c1223 23.069 23.069 -23.069 -3.507 -1.65E-05 -3.483 -3.567 3.61E-04 9.49E-03 1 orf2-encoded protein 32.272 877 555 738 32.272 32.272 9.203 877 335 468 9.203 9.203 ruditapes_lrc39142 83.652 83.652 -83.652 -3.506 -5.97E-05 -3.482 -6.792 1.11E-11 9.62E-10 3.61E-07 60s ribosomal protein l7a 117.037 483 132 "1,474" 117.037 117.037 33.385 483 146 935 33.385 33.385 ruditapes_s39680 10.01 10.01 -10.01 -3.502 -7.14E-06 -3.478 -2.349 0.019 0.251 1 ribosomal protein l7a /// 0042788 // polysomal ribosome /// 0006414 // translational elongation /// 0005624 // membrane fraction /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding 14.011 375 0 137 14.011 14.011 4.001 375 1 87 4.001 4.001 ruditapes2_lrc5054 44.412 44.412 -44.412 -3.482 -3.17E-05 -3.459 -4.938 7.88E-07 3.70E-05 0.026 ribosomal protein l12e /// 0005811 // lipid particle /// 0022625 // cytosolic large ribosomal subunit /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0003735 // structural constituent of ribosome 62.305 666 2 "1,082" 62.305 62.305 17.893 666 0 691 17.893 17.893 ruditapes2_c375 5.134 5.134 -5.134 -3.47 -3.66E-06 -3.447 -1.677 0.094 0.776 1 cg5499-pa /// 0005694 // chromosome 7.213 755 0 142 7.213 7.213 2.079 755 0 91 2.079 2.079 ruditapes_c4565 8.792 8.792 -8.792 -3.459 -6.27E-06 -3.436 -2.193 0.028 0.344 1 oncoprotein induced transcript 3 12.368 738 74 238 12.368 12.368 3.575 738 71 153 3.575 3.575 ruditapes_c314 24.859 24.859 -24.859 -3.456 -1.77E-05 -3.433 -3.686 2.28E-04 6.40E-03 1 mitochondrial ribosomal protein l24 /// 0044424 // intracellular part 34.98 990 903 903 34.98 34.98 10.121 990 581 581 10.121 10.121 ruditapes_lrc12146 135.627 135.627 -135.627 -3.428 -9.67E-05 -3.405 -8.587 8.92E-18 1.29E-15 2.91E-13 ribosomal protein s7 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 191.477 696 20 "3,475" 191.477 191.477 55.85 696 15 "2,254" 55.85 55.85 ruditapes_c7467 10.289 10.289 -10.289 -3.405 -7.34E-06 -3.382 -2.36 0.018 0.246 1 coiled-coil domain containing 137 14.567 516 196 196 14.567 14.567 4.278 516 128 128 4.278 4.278 ruditapes2_c1553 5.575 5.575 -5.575 -3.404 -3.98E-06 -3.381 -1.737 0.082 0.718 1 gram negative bacteria binding protein 2 7.895 "1,093" 225 225 7.895 7.895 2.319 "1,093" 147 147 2.319 2.319 ruditapes2_c3709 73.377 73.377 -73.377 -3.389 -5.23E-05 -3.366 -6.292 3.13E-10 2.41E-08 1.02E-05 glutathione peroxidase 3 /// 0006749 // glutathione metabolic process /// 0005625 // soluble fraction /// 0005615 // extracellular space /// 0042744 // hydrogen peroxide catabolic process /// 0008430 // selenium binding /// 0008134 // transcription factor binding /// 0006982 // response to lipid hydroperoxide /// 0004602 // glutathione peroxidase activity /// 0051289 // protein homotetramerization /// 0043295 // glutathione binding 104.094 882 833 "2,394" 104.094 104.094 30.718 882 444 "1,571" 30.718 30.718 ruditapes2_lrc6231 25.125 25.125 -25.125 -3.368 -1.79E-05 -3.345 -3.674 2.39E-04 6.65E-03 1 60s ribosomal protein l13 /// 0030529 // ribonucleoprotein complex /// 0051726 // regulation of cell cycle 35.736 616 9 574 35.736 35.736 10.611 616 4 379 10.611 10.611 ruditapes_lrc32635 50.996 50.996 -50.996 -3.355 -3.64E-05 -3.333 -5.228 1.71E-07 8.90E-06 5.58E-03 ribosomal protein l4 /// 0006414 // translational elongation /// 0030529 // ribonucleoprotein complex /// 0005515 // protein binding /// 0005829 // cytosol 72.648 634 160 "1,201" 72.648 72.648 21.652 634 189 796 21.652 21.652 ruditapes_lrc34355 10.209 10.209 -10.209 -3.354 -7.28E-06 -3.331 -2.339 0.019 0.256 1 lysozyme [Venerupis philippinarum] 14.547 493 141 187 14.547 14.547 4.338 493 102 124 4.338 4.338 ruditapes2_lrc5554 7.866 7.866 -7.866 -3.351 -5.61E-06 -3.329 -2.053 0.04 0.441 1 ribosomal protein l32 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003735 // structural constituent of ribosome 11.212 366 0 107 11.212 11.212 3.345 366 0 71 3.345 3.345 ruditapes2_c5486 6.938 6.938 -6.938 -3.343 -4.95E-06 -3.321 -1.926 0.054 0.545 1 ribosomal protein s3a /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0006413 // translational initiation /// 0005515 // protein binding /// 0006917 // induction of apoptosis /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 9.898 833 4 215 9.898 9.898 2.961 833 2 143 2.961 2.961 ruditapes_lrc11227 5.294 5.294 -5.294 -3.336 -3.78E-06 -3.313 -1.681 0.093 0.773 1 mitochondrial ubiquinol-cytochrome c reductase hinge protein "/// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c /// 0005750 // mitochondrial respiratory chain complex III /// 0008121 // ubiquinol-cytochrome-c reductase activity" 7.561 700 23 138 7.561 7.561 2.267 700 21 92 2.267 2.267 ruditapes_c1436 15.544 15.544 -15.544 -3.331 -1.11E-05 -3.308 -2.879 3.98E-03 0.073 1 aldehyde dehydrogenase 1a1 "/// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor /// 0008152 // metabolic process /// 0044424 // intracellular part" 22.213 587 245 340 22.213 22.213 6.669 587 139 227 6.669 6.669 ruditapes_lrc34981 8.23 8.23 -8.23 -3.328 -5.87E-06 -3.305 -2.094 0.036 0.411 1 prefoldin subunit 1 /// 0005737 // cytoplasm 11.765 678 28 208 11.765 11.765 3.536 678 8 139 3.536 3.536 ruditapes_lrc34345 12.736 12.736 -12.736 -3.326 -9.08E-06 -3.303 -2.605 9.19E-03 0.145 1 tubulin polymerization-promoting protein family member 3 /// 0002119 // nematode larval development /// 0005730 // nucleolus /// 0000003 // reproduction /// 0005737 // cytoplasm 18.211 "1,074" 57 510 18.211 18.211 5.476 "1,074" 41 341 5.476 5.476 ruditapes2_lrc4348 23.939 23.939 -23.939 -3.312 -1.71E-05 -3.29 -3.567 3.62E-04 9.50E-03 1 ribosomal protein l4 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 34.291 718 80 642 34.291 34.291 10.352 718 56 431 10.352 10.352 ruditapes_lrc6872 361.924 361.924 -361.924 -3.306 -2.58E-04 -3.284 -13.862 1.09E-43 4.17E-41 3.54E-39 60s ribosomal protein l23a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0000166 // nucleotide binding /// 0003735 // structural constituent of ribosome 518.849 584 698 "7,901" 518.849 518.849 156.925 584 277 "5,314" 156.925 156.925 ruditapes_c2613 27.794 27.794 -27.794 -3.304 -1.98E-05 -3.282 -3.84 1.23E-04 3.71E-03 1 tandem repeat galectin /// 0005529 // sugar binding 39.854 612 219 636 39.854 39.854 12.061 612 141 428 12.061 12.061 ruditapes_lrc32264 21.08 21.08 -21.08 -3.303 -1.50E-05 -3.281 -3.344 8.27E-04 0.019 1 atp binding 30.234 893 475 704 30.234 30.234 9.154 893 255 474 9.154 9.154 ruditapes2_lrc4717 116.201 116.201 -116.201 -3.29 -8.29E-05 -3.268 -7.84 4.50E-15 5.34E-13 1.47E-10 translationally controlled tumor protein 166.947 957 417 "4,166" 166.947 166.947 50.746 957 377 "2,816" 50.746 50.746 ruditapes_c7762 5.808 5.808 -5.808 -3.276 -4.14E-06 -3.253 -1.75 0.08 0.702 1 tpa_exp: tyrosine recombinase 8.36 500 109 109 8.36 8.36 2.552 500 74 74 2.552 2.552 ruditapes2_lrc4997 81.388 81.388 -81.388 -3.267 -5.80E-05 -3.245 -6.546 5.91E-11 4.90E-09 1.93E-06 ribosomal protein s13 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0003729 // mRNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0033119 // negative regulation of RNA splicing 117.286 515 44 "1,575" 117.286 117.286 35.898 515 27 "1,072" 35.898 35.898 ruditapes_lrc34654 183.616 183.616 -183.616 -3.261 -1.31E-04 -3.239 -9.826 8.73E-23 1.73E-20 2.85E-18 60s ribosomal protein l32 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 264.838 403 57 "2,783" 264.838 264.838 81.222 403 56 "1,898" 81.222 81.222 ruditapes2_c2679 5.114 5.114 -5.114 -3.259 -3.65E-06 -3.237 -1.639 0.101 0.812 1 pol-like protein 7.378 998 192 192 7.378 7.378 2.264 998 131 131 2.264 2.264 ruditapes_lrc35870 5.172 5.172 -5.172 -3.256 -3.69E-06 -3.234 -1.648 0.099 0.803 1 nadh: oxidoreductase subunit /// 0005743 // mitochondrial inner membrane 7.464 632 80 123 7.464 7.464 2.292 632 29 84 2.292 2.292 ruditapes_lrc36808 30.851 30.851 -30.851 -3.254 -2.20E-05 -3.232 -4.025 5.71E-05 1.85E-03 1 thaumatin-like protein /// 0048046 // apoplast /// 0010224 // response to UV-B /// 0009627 // systemic acquired resistance /// 0031540 // regulation of anthocyanin biosynthetic process /// 0005515 // protein binding /// 0016023 // cytoplasmic membrane-bounded vesicle /// 0005618 // cell wall 44.536 465 5 540 44.536 44.536 13.685 465 3 369 13.685 13.685 ruditapes_lrc33561 178.397 178.397 -178.397 -3.239 -1.27E-04 -3.217 -9.662 4.36E-22 8.31E-20 1.42E-17 ribosomal protein l4 /// 0030529 // ribonucleoprotein complex /// 0005488 // binding /// 0006412 // translation /// 0005829 // cytosol 258.086 836 430 "5,626" 258.086 258.086 79.689 836 358 "3,863" 79.689 79.689 ruditapes_lrc27061 81.368 81.368 -81.368 -3.235 -5.80E-05 -3.214 -6.523 6.89E-11 5.62E-09 2.25E-06 translation elongation factor ef-2 /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0003746 // translation elongation factor activity 117.767 452 302 "1,388" 117.767 117.767 36.399 452 205 954 36.399 36.399 ruditapes_c14604 11.07 11.07 -11.07 -3.234 -7.89E-06 -3.212 -2.405 0.016 0.222 1 retinal homeobox protein 16.026 682 285 285 16.026 16.026 4.956 682 196 196 4.956 4.956 ruditapes_c26408 8.169 8.169 -8.169 -3.218 -5.83E-06 -3.196 -2.063 0.039 0.435 1 gene model 11.852 398 116 123 11.852 11.852 3.683 398 81 85 3.683 3.683 ruditapes2_c188 131.761 131.761 -131.761 -3.212 -9.40E-05 -3.19 -8.28 1.24E-16 1.64E-14 4.03E-12 ribosomal protein s2 /// 0031981 // nuclear lumen /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0017134 // fibroblast growth factor binding /// 0005829 // cytosol 191.335 735 155 "3,667" 191.335 191.335 59.574 735 110 "2,539" 59.574 59.574 ruditapes_c12763 14.058 14.058 -14.058 -3.211 -1.00E-05 -3.189 -2.704 6.85E-03 0.115 1 hypothetical protein BRAFLDRAFT_118696 [Branchiostoma floridae] 20.417 556 219 296 20.417 20.417 6.359 556 172 205 6.359 6.359 ruditapes2_c404 369.535 369.535 -369.535 -3.207 -2.64E-04 -3.185 -13.86 1.11E-43 4.20E-41 3.61E-39 dead box atp-dependent rna 536.973 "1,175" "16,387" "16,452" 536.973 536.973 167.438 "1,175" "11,345" "11,408" 167.438 167.438 ruditapes2_lrc3379 451.357 451.357 -451.357 -3.201 -3.22E-04 -3.18 -15.309 6.68E-53 3.03E-50 2.18E-48 tubulin beta-2c chain /// 0000166 // nucleotide binding /// 0007017 // microtubule-based process 656.384 754 "1,960" "12,905" 656.384 656.384 205.028 754 "1,856" "8,964" 205.028 205.028 ruditapes2_c147 618.039 618.039 -618.039 -3.191 -4.41E-04 -3.17 -17.895 1.30E-71 7.67E-69 4.22E-67 heat shock protein 70 900.089 885 "12,822" "20,771" 900.089 900.089 282.051 885 "8,040" "14,474" 282.051 282.051 ruditapes_s37523 85.933 85.933 -85.933 -3.184 -6.13E-05 -3.163 -6.666 2.63E-11 2.24E-09 8.57E-07 ribosomal protein l27a /// 0022626 // cytosolic ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 125.278 540 447 "1,764" 125.278 125.278 39.346 540 387 "1,232" 39.346 39.346 ruditapes2_c129 33.064 33.064 -33.064 -3.18 -2.36E-05 -3.158 -4.133 3.59E-05 1.22E-03 1 lethal 35di 48.234 939 204 "1,181" 48.234 48.234 15.17 939 183 826 15.17 15.17 ruditapes2_c203 "2,611.93" "2,611.93" "-2,611.93" -3.171 -1.86E-03 -3.15 -36.739 2.14E-295 3.32E-292 6.97E-291 cg12324 protein /// 0005811 // lipid particle /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit "3,814.89" 483 "3,463" "48,046" "3,814.89" "3,814.89" "1,202.95" 483 "5,877" "33,691" "1,202.95" "1,202.95" ruditapes2_lrc5220 33.688 33.688 -33.688 -3.169 -2.40E-05 -3.147 -4.167 3.09E-05 1.06E-03 1 atp synthase beta subunit "/// 0005524 // ATP binding /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism" 49.221 755 51 969 49.221 49.221 15.533 755 58 680 15.533 15.533 ruditapes2_lrc5750 20.332 20.332 -20.332 -3.168 -1.45E-05 -3.147 -3.237 1.21E-03 0.027 1 ribosomal protein s18 /// 0007275 // multicellular organismal development /// 0006414 // translational elongation /// 0051726 // regulation of cell cycle /// 0019843 // rRNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0006417 // regulation of translation 29.709 537 10 416 29.709 29.709 9.378 537 3 292 9.378 9.378 ruditapes_c15609 10.128 10.128 -10.128 -3.168 -7.22E-06 -3.147 -2.284 0.022 0.285 1 splicing factor subunit 10kda "/// 0005681 // spliceosomal complex /// 0000398 // nuclear mRNA splicing, via spliceosome /// 0007052 // mitotic spindle organization" 14.799 539 208 208 14.799 14.799 4.671 539 146 146 4.671 4.671 ruditapes_c5732 7.898 7.898 -7.898 -3.152 -5.63E-06 -3.131 -2.014 0.044 0.471 1 taf10 rna polymerase ii /// 0048471 // perinuclear region of cytoplasm /// 0005515 // protein binding /// 0006368 // RNA elongation from RNA polymerase II promoter /// 0005669 // transcription factor TFIID complex /// 0006915 // apoptosis /// 0000082 // G1/S transition of mitotic cell cycle /// 0006367 // transcription initiation from RNA polymerase II promoter /// 0003702 // RNA polymerase II transcription factor activity 11.569 484 3 146 11.569 11.569 3.67 484 2 103 3.67 3.67 ruditapes2_c212 37.377 37.377 -37.377 -3.146 -2.67E-05 -3.125 -4.377 1.20E-05 4.55E-04 0.391 aldehyde dehydrogenase 1a1 /// 0055114 // oxidation reduction /// 0002072 // optic cup morphogenesis involved in camera-type eye development /// 0005634 // nucleus /// 0043065 // positive regulation of apoptosis /// 0042573 // retinoic acid metabolic process /// 0021768 // nucleus accumbens development /// 0005829 // cytosol /// 0048048 // embryonic eye morphogenesis /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity /// 0004028 // 3-chloroallyl aldehyde dehydrogenase activity /// 0060166 // olfactory pit development /// 0001758 // retinal dehydrogenase activity 54.792 "1,017" "1,157" "1,453" 54.792 54.792 17.415 "1,017" 777 "1,027" 17.415 17.415 ruditapes2_lrc3255 "3,558.42" "3,558.42" "-3,558.42" -3.139 -2.54E-03 -3.118 -42.745 0 0 0 beta tubulin /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0005874 // microtubule /// 0007018 // microtubule-based movement "5,221.68" "1,194" "27,240" "162,571" "5,221.68" "5,221.68" "1,663.26" "1,194" "22,395" "115,155" "1,663.26" "1,663.26" ruditapes_lrc33090 84.283 84.283 -84.283 -3.138 -6.01E-05 -3.117 -6.568 5.12E-11 4.26E-09 1.67E-06 ribosomal protein l21 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 123.702 532 13 "1,716" 123.702 123.702 39.419 532 6 "1,216" 39.419 39.419 ruditapes_lrc14244 8.453 8.453 -8.453 -3.126 -6.03E-06 -3.104 -2.077 0.038 0.423 1 ribosomal protein sa /// 0005840 // ribosome /// 0009987 // cellular process 12.43 941 49 305 12.43 12.43 3.977 941 31 217 3.977 3.977 ruditapes_lrc33828 28.699 28.699 -28.699 -3.125 -2.05E-05 -3.104 -3.826 1.30E-04 3.90E-03 1 alpha actin "/// 0005524 // ATP binding /// 0042643 // actomyosin, actin part /// 0016887 // ATPase activity /// 0014829 // vascular smooth muscle contraction /// 0030240 // muscle thin filament assembly /// 0031674 // I band /// 0030048 // actin filament-based movement /// 0006915 // apoptosis /// 0060047 // heart contraction /// 0008217 // regulation of blood pressure /// 0017022 // myosin binding /// 0055003 // cardiac myofibril assembly /// 0055008 // cardiac muscle tissue morphogenesis" 42.204 627 225 690 42.204 42.204 13.505 627 158 491 13.505 13.505 ruditapes_c24872 12.115 12.115 -12.115 -3.123 -8.64E-06 -3.102 -2.486 0.013 0.188 1 serine protease inhibitor 2 17.821 269 125 125 17.821 17.821 5.706 269 89 89 5.706 5.706 ruditapes_c14697 7.247 7.247 -7.247 -3.122 -5.17E-06 -3.101 -1.922 0.055 0.547 1 protein 10.661 500 139 139 10.661 10.661 3.415 500 99 99 3.415 3.415 ruditapes_c14388 6.733 6.733 -6.733 -3.119 -4.80E-06 -3.098 -1.852 0.064 0.608 1 hypothetical protein BRAFLDRAFT_176686 [Branchiostoma floridae] 9.911 445 113 115 9.911 9.911 3.178 445 80 82 3.178 3.178 ruditapes_c26195 5.451 5.451 -5.451 -3.113 -3.89E-06 -3.092 -1.665 0.096 0.786 1 multidrug resistance protein "/// 0005524 // ATP binding /// 0006810 // transport /// 0016021 // integral to membrane /// 0042626 // ATPase activity, coupled to transmembrane movement of substances" 8.031 234 49 49 8.031 8.031 2.579 234 35 35 2.579 2.579 ruditapes_lrc36006 31.004 31.004 -31.004 -3.11 -2.21E-05 -3.089 -3.97 7.18E-05 2.29E-03 1 ribosomal protein l4 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 45.698 642 311 765 45.698 45.698 14.694 642 221 547 14.694 14.694 ruditapes_lrc20388 31.374 31.374 -31.374 -3.109 -2.24E-05 -3.088 -3.993 6.52E-05 2.09E-03 1 60s ribosomal protein l9 46.251 233 22 281 46.251 46.251 14.877 233 13 201 14.877 14.877 ruditapes_lrc33927 269.085 269.085 -269.085 -3.107 -1.92E-04 -3.086 -11.694 1.38E-31 4.12E-29 4.49E-27 ribosomal protein l23a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0000166 // nucleotide binding /// 0003735 // structural constituent of ribosome 396.788 410 373 "4,242" 396.788 396.788 127.703 410 217 "3,036" 127.703 127.703 ruditapes_c10644 11.933 11.933 -11.933 -3.106 -8.51E-06 -3.085 -2.462 0.014 0.198 1 accessory gland protein 17.6 353 162 162 17.6 17.6 5.667 353 116 116 5.667 5.667 ruditapes2_lrc4656 255.746 255.746 -255.746 -3.097 -1.82E-04 -3.076 -11.387 4.88E-30 1.37E-27 1.59E-25 40s ribosomal protein s8 /// 0044424 // intracellular part 377.691 831 "3,961" "8,184" 377.691 377.691 121.945 831 "1,134" "5,876" 121.945 121.945 ruditapes_lrc33832 22.318 22.318 -22.318 -3.097 -1.59E-05 -3.076 -3.363 7.70E-04 0.018 1 atp:adp antiporter /// 0005739 // mitochondrion /// 0016020 // membrane 32.96 619 5 532 32.96 32.96 10.643 619 1 382 10.643 10.643 ruditapes2_c1879 13.216 13.216 -13.216 -3.086 -9.42E-06 -3.065 -2.585 9.74E-03 0.152 1 c030046i01rik protein 19.55 716 365 365 19.55 19.55 6.335 716 263 263 6.335 6.335 ruditapes_lrc33333 164.512 164.512 -164.512 -3.081 -1.17E-04 -3.06 -9.115 7.90E-20 1.32E-17 2.58E-15 ribosomal protein s17 /// 0006414 // translational elongation /// 0034101 // erythrocyte homeostasis /// 0006413 // translational initiation /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 243.567 601 162 "3,817" 243.567 243.567 79.055 601 83 "2,755" 79.055 79.055 ruditapes_c25464 12.17 12.17 -12.17 -3.065 -8.68E-06 -3.044 -2.474 0.013 0.193 1 gene model 18.064 673 311 317 18.064 18.064 5.894 673 227 230 5.894 5.894 ruditapes_lrc33408 40.228 40.228 -40.228 -3.063 -2.87E-05 -3.042 -4.497 6.89E-06 2.76E-04 0.225 nucleoside diphosphate kinase /// 0005524 // ATP binding /// 0007424 // open tracheal system development /// 0006468 // protein amino acid phosphorylation /// 0006183 // GTP biosynthetic process /// 0006241 // CTP biosynthetic process /// 0004550 // nucleoside diphosphate kinase activity /// 0006228 // UTP biosynthetic process 59.729 818 663 "1,274" 59.729 59.729 19.502 818 400 925 19.502 19.502 ruditapes_lrc33492 17.946 17.946 -17.946 -3.053 -1.28E-05 -3.032 -3 2.70E-03 0.053 1 ribosomal protein l5 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0042273 // ribosomal large subunit biogenesis 26.687 582 1 405 26.687 26.687 8.741 582 1 295 8.741 8.741 ruditapes_c36518 96.604 96.604 -96.604 -3.044 -6.89E-05 -3.024 -6.953 3.57E-12 3.24E-10 1.16E-07 ribosomal protein l35 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0003729 // mRNA binding /// 0022625 // cytosolic large ribosomal subunit /// 0003735 // structural constituent of ribosome 143.857 450 321 "1,688" 143.857 143.857 47.253 450 261 "1,233" 47.253 47.253 ruditapes_c11131 6.28 6.28 -6.28 -3.039 -4.48E-06 -3.019 -1.772 0.076 0.684 1 cathepsin l /// 0006508 // proteolysis /// 0004197 // cysteine-type endopeptidase activity 9.359 504 123 123 9.359 9.359 3.08 504 90 90 3.08 3.08 ruditapes_lrc38631 24.139 24.139 -24.139 -3.03 -1.72E-05 -3.01 -3.47 5.21E-04 0.013 1 ribosomal protein s20 /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 36.029 380 21 357 36.029 36.029 11.89 380 11 262 11.89 11.89 ruditapes2_c4353 59.98 59.98 -59.98 -3.025 -4.28E-05 -3.005 -5.466 4.61E-08 2.61E-06 1.50E-03 tubulin polymerization-promoting protein family member 2 /// 0002119 // nematode larval development /// 0005730 // nucleolus /// 0000003 // reproduction /// 0005737 // cytoplasm 89.599 "1,115" 399 "2,605" 89.599 89.599 29.619 "1,115" 241 "1,915" 29.619 29.619 ruditapes2_c200 43.61 43.61 -43.61 -3.023 -3.11E-05 -3.003 -4.659 3.17E-06 1.36E-04 0.103 ribosomal l24 domain containing 1 /// 0042254 // ribosome biogenesis /// 0005634 // nucleus /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 65.167 808 741 "1,373" 65.167 65.167 21.557 808 521 "1,010" 21.557 21.557 ruditapes_lrc35970 9.789 9.789 -9.789 -3.014 -6.98E-06 -2.994 -2.205 0.027 0.336 1 angiopoietin-like 2 /// 0005576 // extracellular region 14.649 699 59 267 14.649 14.649 4.86 699 42 197 4.86 4.86 ruditapes2_lrc3545 8.005 8.005 -8.005 -3.011 -5.71E-06 -2.991 -1.993 0.046 0.488 1 fkbp-type peptidyl-prolyl cis-trans isomerase /// 0005739 // mitochondrion /// 0005634 // nucleus /// 0000747 // conjugation with cellular fusion /// 0009092 // homoserine metabolic process /// 0005527 // macrolide binding /// 0006412 // translation /// 0005829 // cytosol /// 0006325 // chromatin organization /// 0003755 // peptidyl-prolyl cis-trans isomerase activity /// 0006457 // protein folding 11.985 624 35 195 11.985 11.985 3.98 624 27 144 3.98 3.98 ruditapes2_lrc5755 12.626 12.626 -12.626 -3 -9.00E-06 -2.98 -2.5 0.012 0.182 1 60s ribosomal protein l23 /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0003735 // structural constituent of ribosome 18.94 407 0 201 18.94 18.94 6.314 407 0 149 6.314 6.314 ruditapes2_lrc4741 10.952 10.952 -10.952 -2.997 -7.81E-06 -2.977 -2.327 0.02 0.262 1 ribosomal protein l23 /// 0006414 // translational elongation /// 0006610 // ribosomal protein import into nucleus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0000022 // mitotic spindle elongation /// 0003735 // structural constituent of ribosome 16.436 434 0 186 16.436 16.436 5.484 434 0 138 5.484 5.484 ruditapes_lrc33985 7.066 7.066 -7.066 -2.975 -5.04E-06 -2.955 -1.864 0.062 0.598 1 ribosomal protein s5 /// 0006414 // translational elongation /// 0006413 // translational initiation /// 0003729 // mRNA binding /// 0006450 // regulation of translational fidelity /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 10.644 699 0 194 10.644 10.644 3.577 699 0 145 3.577 3.577 ruditapes2_c956 433.03 433.03 -433.03 -2.966 -3.09E-04 -2.946 -14.578 3.90E-48 1.63E-45 1.27E-43 ribosomal protein l19 /// 0006414 // translational elongation /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 653.318 649 "2,125" "11,056" 653.318 653.318 220.289 649 "2,402" "8,290" 220.289 220.289 ruditapes_lrc33579 9.518 9.518 -9.518 -2.965 -6.78E-06 -2.945 -2.161 0.031 0.365 1 ribosomal protein l23 /// 0006414 // translational elongation /// 0006610 // ribosomal protein import into nucleus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0000022 // mitotic spindle elongation /// 0003735 // structural constituent of ribosome 14.361 470 0 176 14.361 14.361 4.843 470 0 132 4.843 4.843 ruditapes2_lrc4104 5.775 5.775 -5.775 -2.957 -4.12E-06 -2.937 -1.681 0.093 0.773 1 mitochondrial ubiquinol cytochrome c reductase complex 8.725 567 6 129 8.725 8.725 2.95 567 8 97 2.95 2.95 ruditapes_c19262 186.515 186.515 -186.515 -2.948 -1.33E-04 -2.928 -9.544 1.37E-21 2.56E-19 4.47E-17 solute carrier family anion member 1 /// 0005452 // inorganic anion exchanger activity /// 0016021 // integral to membrane /// 0006820 // anion transport /// 0030097 // hemopoiesis 282.253 642 "3,589" "4,725" 282.253 282.253 95.738 642 "2,601" "3,564" 95.738 95.738 ruditapes_c1897 505.58 505.58 -505.58 -2.946 -3.60E-04 -2.926 -15.711 1.28E-55 6.15E-53 4.18E-51 ribosomal protein l37 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0005829 // cytosol 765.425 387 "7,724" "7,724" 765.425 765.425 259.845 387 "5,831" "5,831" 259.845 259.845 ruditapes2_c287 11.445 11.445 -11.445 -2.944 -8.16E-06 -2.924 -2.363 0.018 0.244 1 mitochondrial ribosomal protein s6 /// 0005739 // mitochondrion /// 0015935 // small ribosomal subunit 17.331 624 119 282 17.331 17.331 5.887 624 33 213 5.887 5.887 ruditapes_c429 7.065 7.065 -7.065 -2.941 -5.04E-06 -2.921 -1.856 0.064 0.605 1 mitochondrial ribosomal protein s18c /// 0005763 // mitochondrial small ribosomal subunit 10.706 720 201 201 10.706 10.706 3.641 720 152 152 3.641 3.641 ruditapes_c23206 6.742 6.742 -6.742 -2.934 -4.81E-06 -2.915 -1.811 0.07 0.645 1 cyclin d3 /// 0044424 // intracellular part 10.227 480 127 128 10.227 10.227 3.485 480 97 97 3.485 3.485 ruditapes_c17007 24.712 24.712 -24.712 -2.925 -1.76E-05 -2.905 -3.463 5.34E-04 0.013 1 loc398558 protein 37.549 622 609 609 37.549 37.549 12.837 622 463 463 12.837 12.837 ruditapes2_c647 333.152 333.152 -333.152 -2.922 -2.38E-04 -2.903 -12.713 5.05E-37 1.70E-34 1.65E-32 arginine kinase /// 0000166 // nucleotide binding /// 0016301 // kinase activity 506.463 747 "4,423" "9,865" 506.463 506.463 173.312 747 "2,989" "7,507" 173.312 173.312 ruditapes_c29771 8.787 8.787 -8.787 -2.91 -6.26E-06 -2.89 -2.061 0.039 0.436 1 aldo keto reductase /// 0055114 // oxidation reduction /// 0016491 // oxidoreductase activity 13.388 656 229 229 13.388 13.388 4.601 656 175 175 4.601 4.601 ruditapes_c852 6.373 6.373 -6.373 -2.908 -4.54E-06 -2.888 -1.755 0.079 0.698 1 serine threonine-protein 9.713 537 32 136 9.713 9.713 3.34 537 51 104 3.34 3.34 ruditapes2_c4685 6.045 6.045 -6.045 -2.901 -4.31E-06 -2.882 -1.707 0.088 0.747 1 galactoside- 3 9.225 819 29 197 9.225 9.225 3.18 819 24 151 3.18 3.18 ruditapes2_lrc4239 6.904 6.904 -6.904 -2.898 -4.92E-06 -2.878 -1.824 0.068 0.634 1 translationally controlled tumor protein 10.542 "1,095" 0 301 10.542 10.542 3.638 "1,095" 0 231 3.638 3.638 ruditapes_c4804 12.776 12.776 -12.776 -2.882 -9.11E-06 -2.863 -2.476 0.013 0.192 1 transmembrane protein 103 19.564 592 240 302 19.564 19.564 6.788 592 171 233 6.788 6.788 ruditapes_c33520 39.015 39.015 -39.015 -2.88 -2.78E-05 -2.861 -4.325 1.53E-05 5.62E-04 0.498 alkaline ceramidase 59.766 428 352 667 59.766 59.766 20.751 428 245 515 20.751 20.751 ruditapes_c28006 791.366 791.366 -791.366 -2.875 -5.64E-04 -2.856 -19.471 1.96E-84 1.36E-81 6.40E-80 cytochrome c subunit ii /// 0046914 // transition metal ion binding /// 0022900 // electron transport chain /// 0005739 // mitochondrion /// 0016020 // membrane "1,213.35" 708 "17,753" "22,400" "1,213.35" "1,213.35" 421.985 708 "14,392" "17,324" 421.985 421.985 ruditapes2_c761 6.638 6.638 -6.638 -2.875 -4.73E-06 -2.856 -1.783 0.075 0.674 1 pol-like protein 10.178 682 141 181 10.178 10.178 3.54 682 122 140 3.54 3.54 ruditapes2_lrc4816 20.392 20.392 -20.392 -2.874 -1.45E-05 -2.855 -3.124 1.78E-03 0.038 1 apolipophorin precursor protein 31.272 856 23 698 31.272 31.272 10.879 856 25 540 10.879 10.879 ruditapes_c13966 9.204 9.204 -9.204 -2.865 -6.56E-06 -2.845 -2.096 0.036 0.411 1 repeat organellar 14.139 594 219 219 14.139 14.139 4.936 594 170 170 4.936 4.936 ruditapes2_lrc5326 52.149 52.149 -52.149 -2.864 -3.72E-05 -2.844 -4.988 6.09E-07 2.90E-05 0.02 ribosomal protein l11 /// 0006414 // translational elongation /// 0006605 // protein targeting /// 0005730 // nucleolus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development /// 0042273 // ribosomal large subunit biogenesis 80.131 559 47 "1,168" 80.131 80.131 27.982 559 29 907 27.982 27.982 ruditapes_lrc33808 642.023 642.023 -642.023 -2.844 -4.58E-04 -2.825 -17.46 2.94E-68 1.62E-65 9.58E-64 alpha tubulin /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0005874 // microtubule /// 0007018 // microtubule-based movement 990.141 506 "2,108" "13,064" 990.141 990.141 348.119 506 "1,882" "10,214" 348.119 348.119 ruditapes2_lrc6086 8.955 8.955 -8.955 -2.828 -6.38E-06 -2.809 -2.057 0.04 0.439 1 alpha 3 type vi collagen isoform 1 precursor /// 0005578 // proteinaceous extracellular matrix 13.854 609 70 220 13.854 13.854 4.899 609 31 173 4.899 4.899 ruditapes_lrc33086 12.416 12.416 -12.416 -2.828 -8.85E-06 -2.808 -2.421 0.015 0.216 1 ribosomal protein l21 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 19.209 561 0 281 19.209 19.209 6.794 561 0 221 6.794 6.794 ruditapes_c6040 10.332 10.332 -10.332 -2.825 -7.36E-06 -2.806 -2.208 0.027 0.333 1 ribosomal protein l24 /// 0010458 // exit from mitosis /// 0006414 // translational elongation /// 0021554 // optic nerve development /// 0005515 // protein binding /// 0031575 // G1/S transition checkpoint /// 0022625 // cytosolic large ribosomal subunit /// 0031290 // retinal ganglion cell axon guidance /// 0000027 // ribosomal large subunit assembly /// 0060041 // retina development in camera-type eye /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development 15.992 518 1 216 15.992 15.992 5.66 518 4 170 5.66 5.66 ruditapes_c8441 78.081 78.081 -78.081 -2.819 -5.56E-05 -2.8 -6.065 1.32E-09 9.63E-08 4.30E-05 cathepsin l precursor /// 0006508 // proteolysis /// 0004197 // cysteine-type endopeptidase activity 121.006 818 "1,868" "2,581" 121.006 121.006 42.925 818 "1,585" "2,036" 42.925 42.925 ruditapes2_c399 68.312 68.312 -68.312 -2.819 -4.87E-05 -2.8 -5.673 1.40E-08 8.82E-07 4.58E-04 nicotinamide nucleotide transhydrogenase /// 0055114 // oxidation reduction /// 0008750 // NAD(P)+ transhydrogenase (AB-specific) activity /// 0015992 // proton transport /// 0006099 // tricarboxylic acid cycle /// 0005746 // mitochondrial respiratory chain /// 0051287 // NAD or NADH binding /// 0003957 // NAD(P)+ transhydrogenase (B-specific) activity /// 0016021 // integral to membrane /// 0050661 // NADP or NADPH binding /// 0009055 // electron carrier activity 105.864 "1,127" "1,420" "3,111" 105.864 105.864 37.552 "1,127" "1,277" "2,454" 37.552 37.552 ruditapes_c31175 20.755 20.755 -20.755 -2.818 -1.48E-05 -2.799 -3.126 1.77E-03 0.037 1 in family member (ttn-1) 32.175 888 745 745 32.175 32.175 11.419 888 588 588 11.419 11.419 ruditapes_lrc34795 8.214 8.214 -8.214 -2.814 -5.85E-06 -2.795 -1.966 0.049 0.509 1 cathepsin l /// 0006508 // proteolysis /// 0004197 // cysteine-type endopeptidase activity 12.742 933 65 310 12.742 12.742 4.529 933 38 245 4.529 4.529 ruditapes2_c318 "1,008.13" "1,008.13" "-1,008.13" -2.812 -7.18E-04 -2.793 -21.779 3.79E-105 2.94E-102 1.24E-100 ribosomal protein l34a /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome "1,564.60" 449 "4,396" "18,318" "1,564.60" "1,564.60" 556.473 449 "3,865" "14,488" 556.473 556.473 ruditapes2_lrc2988 10.181 10.181 -10.181 -2.785 -7.26E-06 -2.766 -2.179 0.029 0.354 1 ankyrin repeat domain 39 15.886 647 33 268 15.886 15.886 5.704 647 36 214 5.704 5.704 ruditapes_c19007 6.878 6.878 -6.878 -2.785 -4.90E-06 -2.766 -1.791 0.073 0.666 1 tyrosine recombinase 10.731 461 108 129 10.731 10.731 3.853 461 84 103 3.853 3.853 ruditapes2_c122 7.425 7.425 -7.425 -2.782 -5.29E-06 -2.764 -1.86 0.063 0.601 1 acyl- synthetase long-chain family member 1 /// 0044444 // cytoplasmic part /// 0043231 // intracellular membrane-bounded organelle /// 0016020 // membrane 11.59 857 122 259 11.59 11.59 4.166 857 92 207 4.166 4.166 ruditapes2_lrc4282 35.64 35.64 -35.64 -2.781 -2.54E-05 -2.762 -4.074 4.62E-05 1.53E-03 1 ribosomal protein l21 /// 0006414 // translational elongation /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 55.652 829 421 "1,203" 55.652 55.652 20.013 829 203 962 20.013 20.013 ruditapes_lrc33836 27.483 27.483 -27.483 -2.781 -1.96E-05 -2.763 -3.578 3.46E-04 9.15E-03 1 ribosomal protein l35a /// 0044238 // primary metabolic process /// 0010467 // gene expression /// 0044424 // intracellular part /// 0034960 // cellular biopolymer metabolic process 42.911 370 9 414 42.911 42.911 15.428 370 10 331 15.428 15.428 ruditapes_c13200 12.746 12.746 -12.746 -2.77 -9.08E-06 -2.751 -2.433 0.015 0.211 1 serine protease inhibitor 2 19.948 273 142 142 19.948 19.948 7.202 273 114 114 7.202 7.202 ruditapes2_c2079 73.177 73.177 -73.177 -2.763 -5.21E-05 -2.744 -5.822 5.81E-09 3.86E-07 1.89E-04 eukaryotic translation initiation factor subunit 5 47kda /// 0005852 // eukaryotic translation initiation factor 3 complex /// 0006446 // regulation of translational initiation /// 0005515 // protein binding /// 0003743 // translation initiation factor activity /// 0005829 // cytosol 114.685 "1,047" "3,131" "3,131" 114.685 114.685 41.508 "1,047" "2,520" "2,520" 41.508 41.508 ruditapes2_c571 38.988 38.988 -38.988 -2.759 -2.78E-05 -2.74 -4.247 2.17E-05 7.73E-04 0.707 mitochondrial atp synthase gamma-subunit "/// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism" 61.158 718 337 "1,145" 61.158 61.158 22.17 718 310 923 22.17 22.17 ruditapes_c1115 20.981 20.981 -20.981 -2.752 -1.50E-05 -2.733 -3.112 1.86E-03 0.039 1 viral a-type inclusion protein 32.957 "1,358" "1,081" "1,167" 32.957 32.957 11.976 "1,358" 846 943 11.976 11.976 ruditapes2_c4845 9.366 9.366 -9.366 -2.751 -6.67E-06 -2.733 -2.079 0.038 0.422 1 ribosomal protein l26e /// 0006414 // translational elongation /// 0005829 // cytosol 14.715 503 0 193 14.715 14.715 5.349 503 0 156 5.349 5.349 ruditapes2_c3409 78.546 78.546 -78.546 -2.748 -5.60E-05 -2.729 -6.018 1.77E-09 1.27E-07 5.77E-05 protein 123.494 795 "1,617" "2,560" 123.494 123.494 44.947 795 "1,155" "2,072" 44.947 44.947 ruditapes2_c4099 798.21 798.21 -798.21 -2.742 -5.69E-04 -2.724 -19.174 6.19E-82 4.04E-79 2.02E-77 60s acidic ribosomal protein p1 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0003735 // structural constituent of ribosome "1,256.39" 518 "1,024" "16,970" "1,256.39" "1,256.39" 458.178 518 394 "13,762" 458.178 458.178 ruditapes2_lrc4521 7.671 7.671 -7.671 -2.74 -5.47E-06 -2.722 -1.879 0.06 0.586 1 actin /// 0000281 // cytokinesis after mitosis /// 0040007 // growth /// 0002119 // nematode larval development /// 0005515 // protein binding /// 0030036 // actin cytoskeleton organization /// 0040035 // hermaphrodite genitalia development /// 0007517 // muscle organ development /// 0009792 // embryonic development ending in birth or egg hatching 12.079 943 27 297 12.079 12.079 4.407 943 30 241 4.407 4.407 ruditapes_lrc33006 6.867 6.867 -6.867 -2.739 -4.89E-06 -2.72 -1.777 0.076 0.679 1 galactoside- 8 /// 0005634 // nucleus /// 0005515 // protein binding /// 0030198 // extracellular matrix organization /// 0001501 // skeletal system development /// 0005737 // cytoplasm /// 0005578 // proteinaceous extracellular matrix 10.816 773 150 218 10.816 10.816 3.949 773 111 177 3.949 3.949 ruditapes_lrc33008 31.302 31.302 -31.302 -2.734 -2.23E-05 -2.716 -3.791 1.50E-04 4.44E-03 1 mitochondrial atp synthase lipid binding protein precursor "/// 0015992 // proton transport /// 0015078 // hydrogen ion transmembrane transporter activity /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o)" 49.35 774 52 996 49.35 49.35 18.048 774 87 810 18.048 18.048 ruditapes2_c1543 227.599 227.599 -227.599 -2.732 -1.62E-04 -2.713 -10.219 1.64E-24 3.63E-22 5.33E-20 beta 2b /// 0005515 // protein binding /// 0000166 // nucleotide binding /// 0007017 // microtubule-based process 359.045 693 896 "6,488" 359.045 359.045 131.446 693 "1,012" "5,282" 131.446 131.446 ruditapes2_c1920 7.441 7.441 -7.441 -2.732 -5.30E-06 -2.714 -1.848 0.065 0.612 1 chromosome 4 open reading frame 22 11.737 562 172 172 11.737 11.737 4.296 562 140 140 4.296 4.296 ruditapes_c798 9.853 9.853 -9.853 -2.718 -7.02E-06 -2.7 -2.121 0.034 0.393 1 nadh dehydrogenase 1 alpha subcomplex subunit 5 /// 0040007 // growth /// 0002119 // nematode larval development /// 0009792 // embryonic development ending in birth or egg hatching 15.588 866 143 352 15.588 15.588 5.735 866 94 288 5.735 5.735 ruditapes_lrc36503 39.171 39.171 -39.171 -2.716 -2.79E-05 -2.698 -4.229 2.35E-05 8.32E-04 0.767 ribosomal protein l4 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 61.998 686 11 "1,109" 61.998 61.998 22.827 686 13 908 22.827 22.827 ruditapes_c560 9.448 9.448 -9.448 -2.716 -6.73E-06 -2.698 -2.077 0.038 0.423 1 von willebrand factor c domain containing 2 /// 0005615 // extracellular space /// 0005604 // basement membrane /// 0045666 // positive regulation of neuron differentiation /// 0010811 // positive regulation of cell-substrate adhesion /// 0030514 // negative regulation of BMP signaling pathway /// 0005614 // interstitial matrix 14.953 495 193 193 14.953 14.953 5.505 495 158 158 5.505 5.505 ruditapes2_c2896 19.114 19.114 -19.114 -2.71 -1.36E-05 -2.691 -2.951 3.17E-03 0.06 1 cathepsin l-associated protein /// 0005488 // binding /// 0009987 // cellular process /// 0044421 // extracellular region part 30.294 "1,666" "1,059" "1,316" 30.294 30.294 11.18 "1,666" 852 "1,080" 11.18 11.18 ruditapes_c9350 12.62 12.62 -12.62 -2.697 -8.99E-06 -2.679 -2.393 0.017 0.229 1 predicted protein [Nematostella vectensis] 20.055 937 490 490 20.055 20.055 7.436 937 404 404 7.436 7.436 ruditapes_c474 6.38 6.38 -6.38 -2.693 -4.55E-06 -2.675 -1.7 0.089 0.754 1 keratinocyte associated protein 2 /// 0018279 // protein amino acid N-linked glycosylation via asparagine /// 0008250 // oligosaccharyltransferase complex /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity 10.147 "1,062" 134 281 10.147 10.147 3.767 "1,062" 82 232 3.767 3.767 ruditapes_c2216 22.951 22.951 -22.951 -2.688 -1.64E-05 -2.67 -3.222 1.27E-03 0.028 1 max dimerization protein 1 /// 0003700 // transcription factor activity /// 0003714 // transcription corepressor activity /// 0007275 // multicellular organismal development /// 0045449 // regulation of transcription /// 0008283 // cell proliferation /// 0005739 // mitochondrion /// 0005634 // nucleus 36.547 723 365 689 36.547 36.547 13.596 723 345 570 13.596 13.596 ruditapes_c1208 22.765 22.765 -22.765 -2.686 -1.62E-05 -2.667 -3.208 1.34E-03 0.029 1 beta-ig-h3 fasciclin 36.272 535 41 506 36.272 36.272 13.506 535 20 419 13.506 13.506 ruditapes2_lrc3105 595.795 595.795 -595.795 -2.673 -4.24E-04 -2.655 -16.382 2.59E-60 1.30E-57 8.44E-56 beta-tubulin /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0042267 // natural killer cell mediated cytotoxicity /// 0005874 // microtubule /// 0006928 // cell motion /// 0051082 // unfolded protein binding /// 0042288 // MHC class I protein binding /// 0007018 // microtubule-based movement 951.822 790 "14,304" "19,607" 951.822 951.822 356.027 790 "9,071" "16,309" 356.027 356.027 ruditapes2_lrc5470 15.637 15.637 -15.637 -2.667 -1.11E-05 -2.649 -2.65 8.04E-03 0.131 1 ubiquitin a-52 residue ribosomal protein fusion product 1 "/// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process /// 0006355 // regulation of transcription, DNA-dependent /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005811 // lipid particle /// 0006950 // response to stress /// 0006414 // translational elongation /// 0042254 // ribosome biogenesis /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005515 // protein binding /// 0005654 // nucleoplasm /// 0022625 // cytosolic large ribosomal subunit /// 0030433 // ER-associated protein catabolic process /// 0030528 // transcription regulator activity /// 0016567 // protein ubiquitination /// 0006325 // chromatin organization /// 0003735 // structural constituent of ribosome /// 0048167 // regulation of synaptic plasticity /// 0007411 // axon guidance /// 0045941 // positive regulation of transcription /// 0042062 // long-term strengthening of neuromuscular junction" 25.019 443 6 289 25.019 25.019 9.382 443 7 241 9.382 9.382 ruditapes_c8052 9.209 9.209 -9.209 -2.665 -6.56E-06 -2.647 -2.033 0.042 0.456 1 predicted protein [Nematostella vectensis] 14.742 "1,038" 397 399 14.742 14.742 5.533 "1,038" 323 333 5.533 5.533 ruditapes_c1607 5.983 5.983 -5.983 -2.66 -4.26E-06 -2.642 -1.637 0.102 0.813 1 pol-like protein 9.588 976 65 244 9.588 9.588 3.605 976 71 204 3.605 3.605 ruditapes_c17152 12.768 12.768 -12.768 -2.66 -9.10E-06 -2.642 -2.392 0.017 0.229 1 src tyrosine /// 0040007 // growth /// 0002119 // nematode larval development /// 0008406 // gonad development /// 0005488 // binding /// 0040011 // locomotion /// 0040035 // hermaphrodite genitalia development /// 0004672 // protein kinase activity /// 0009792 // embryonic development ending in birth or egg hatching /// 0007052 // mitotic spindle organization 20.461 343 160 183 20.461 20.461 7.693 343 122 153 7.693 7.693 ruditapes2_c230 32.691 32.691 -32.691 -2.658 -2.33E-05 -2.64 -3.827 1.30E-04 3.90E-03 1 sperm associated antigen 8 52.403 846 600 "1,156" 52.403 52.403 19.712 846 465 967 19.712 19.712 ruditapes_lrc34342 384.978 384.978 -384.978 -2.654 -2.74E-04 -2.636 -13.125 2.38E-39 8.42E-37 7.75E-35 ribosomal protein s4 /// 0005840 // ribosome /// 0019843 // rRNA binding /// 0006412 // translation /// 0007420 // brain development /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development 617.703 281 499 "4,526" 617.703 617.703 232.726 281 675 "3,792" 232.726 232.726 ruditapes_lrc35286 10.316 10.316 -10.316 -2.646 -7.35E-06 -2.628 -2.145 0.032 0.376 1 activating transcription factor 4 /// 0016563 // transcription activator activity /// 0050811 // GABA receptor binding /// 0045944 // positive regulation of transcription from RNA polymerase II promoter /// 0003704 // specific RNA polymerase II transcription factor activity /// 0003677 // DNA binding /// 0005667 // transcription factor complex /// 0005737 // cytoplasm /// 0008022 // protein C-terminus binding /// 0006094 // gluconeogenesis 16.583 710 52 307 16.583 16.583 6.267 710 52 258 6.267 6.267 ruditapes_lrc38632 101.598 101.598 -101.598 -2.633 -7.24E-05 -2.615 -6.717 1.86E-11 1.60E-09 6.05E-07 nascent polypeptide-associated complex subunit alpha /// 0003713 // transcription coactivator activity /// 0005634 // nucleus /// 0006412 // translation /// 0005854 // nascent polypeptide-associated complex /// 0017025 // TATA-binding protein binding 163.828 618 162 "2,640" 163.828 163.828 62.23 618 114 "2,230" 62.23 62.23 ruditapes_c7531 14.994 14.994 -14.994 -2.621 -1.07E-05 -2.603 -2.575 0.01 0.155 1 rgm domain member b 24.245 783 495 495 24.245 24.245 9.251 783 420 420 9.251 9.251 ruditapes2_c2074 14.247 14.247 -14.247 -2.62 -1.02E-05 -2.602 -2.509 0.012 0.178 1 mgc81827 protein 23.043 694 417 417 23.043 23.043 8.797 694 354 354 8.797 8.797 ruditapes_lrc32570 33.291 33.291 -33.291 -2.62 -2.37E-05 -2.603 -3.837 1.25E-04 3.75E-03 1 ribosomal protein l5 /// 0042254 // ribosome biogenesis /// 0005840 // ribosome /// 0006412 // translation /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome /// 0008097 // 5S rRNA binding 53.835 800 76 "1,123" 53.835 53.835 20.544 800 60 953 20.544 20.544 ruditapes_lrc33600 40.862 40.862 -40.862 -2.607 -2.91E-05 -2.59 -4.241 2.22E-05 7.92E-04 0.725 malate dehydrogenase nad /// 0030060 // L-malate dehydrogenase activity /// 0055114 // oxidation reduction /// 0006108 // malate metabolic process /// 0006099 // tricarboxylic acid cycle /// 0005488 // binding /// 0006096 // glycolysis /// 0005829 // cytosol 66.282 692 24 "1,196" 66.282 66.282 25.42 692 20 "1,020" 25.42 25.42 ruditapes_lrc12434 212.608 212.608 -212.608 -2.606 -1.51E-04 -2.588 -9.672 3.97E-22 7.61E-20 1.29E-17 ribosomal protein l6 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 345.005 768 754 "6,909" 345.005 345.005 132.397 768 572 "5,896" 132.397 132.397 ruditapes2_lrc3309 6.046 6.046 -6.046 -2.606 -4.31E-06 -2.588 -1.631 0.103 0.821 1 translationally controlled tumor protein /// 0007275 // multicellular organismal development /// 0040007 // growth /// 0005488 // binding 9.812 "1,067" 0 273 9.812 9.812 3.766 "1,067" 0 233 3.766 3.766 ruditapes2_c2343 10.828 10.828 -10.828 -2.604 -7.71E-06 -2.586 -2.182 0.029 0.352 1 PREDICTED: hypothetical protein [Homo sapiens] 17.58 613 241 281 17.58 17.58 6.752 613 201 240 6.752 6.752 ruditapes_c305 14.801 14.801 -14.801 -2.596 -1.05E-05 -2.579 -2.547 0.011 0.165 1 dynein light chain roadblock-type 2 /// 0005868 // cytoplasmic dynein complex /// 0005515 // protein binding /// 0005737 // cytoplasm /// 0005874 // microtubule /// 0003777 // microtubule motor activity /// 0007018 // microtubule-based movement 24.074 822 278 516 24.074 24.074 9.273 822 259 442 9.273 9.273 ruditapes2_lrc3767 77.067 77.067 -77.067 -2.596 -5.49E-05 -2.579 -5.813 6.14E-09 4.06E-07 2.00E-04 protein /// 0005524 // ATP binding /// 0005856 // cytoskeleton /// 0005515 // protein binding /// 0005737 // cytoplasm 125.349 "1,188" "1,622" "3,883" 125.349 125.349 48.282 "1,188" "1,235" "3,326" 48.282 48.282 ruditapes2_c312 24.183 24.183 -24.183 -2.594 -1.72E-05 -2.577 -3.255 1.13E-03 0.026 1 isocitrate dehydrogenase 2 (nadp+) mitochondrial /// 0055114 // oxidation reduction /// 0005739 // mitochondrion /// 0030145 // manganese ion binding /// 0006099 // tricarboxylic acid cycle /// 0004450 // isocitrate dehydrogenase (NADP+) activity /// 0006097 // glyoxylate cycle /// 0000287 // magnesium ion binding /// 0006102 // isocitrate metabolic process 39.35 921 179 945 39.35 39.35 15.167 921 141 810 15.167 15.167 ruditapes_lrc34251 28.281 28.281 -28.281 -2.589 -2.01E-05 -2.572 -3.517 4.37E-04 0.011 1 nucleoside diphosphate kinase /// 0005524 // ATP binding /// 0007424 // open tracheal system development /// 0006468 // protein amino acid phosphorylation /// 0006183 // GTP biosynthetic process /// 0006241 // CTP biosynthetic process /// 0004550 // nucleoside diphosphate kinase activity /// 0006228 // UTP biosynthetic process 46.077 814 145 978 46.077 46.077 17.797 814 215 840 17.797 17.797 ruditapes2_c3526 57.791 57.791 -57.791 -2.588 -4.12E-05 -2.57 -5.026 5.01E-07 2.42E-05 0.016 protein 94.192 831 546 "2,041" 94.192 94.192 36.401 831 413 "1,754" 36.401 36.401 ruditapes_lrc34813 17.909 17.909 -17.909 -2.585 -1.28E-05 -2.568 -2.797 5.16E-03 0.09 1 nucleoside diphosphate kinase /// 0005524 // ATP binding /// 0006183 // GTP biosynthetic process /// 0006241 // CTP biosynthetic process /// 0004550 // nucleoside diphosphate kinase activity /// 0006228 // UTP biosynthetic process 29.207 864 569 658 29.207 29.207 11.298 864 405 566 11.298 11.298 ruditapes_c8603 29.953 29.953 -29.953 -2.584 -2.13E-05 -2.567 -3.616 2.99E-04 8.10E-03 1 transposase 48.864 777 990 990 48.864 48.864 18.91 777 852 852 18.91 18.91 ruditapes2_lrc4851 176.851 176.851 -176.851 -2.577 -1.26E-04 -2.56 -8.776 1.69E-18 2.53E-16 5.51E-14 ribosomal protein s27a /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0006414 // translational elongation /// 0046872 // metal ion binding /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005515 // protein binding /// 0005654 // nucleoplasm /// 0030433 // ER-associated protein catabolic process /// 0030528 // transcription regulator activity /// 0016567 // protein ubiquitination /// 0003735 // structural constituent of ribosome /// 0048167 // regulation of synaptic plasticity /// 0022627 // cytosolic small ribosomal subunit /// 0007411 // axon guidance /// 0045941 // positive regulation of transcription /// 0042062 // long-term strengthening of neuromuscular junction 288.983 510 780 "3,843" 288.983 288.983 112.131 510 417 "3,316" 112.131 112.131 ruditapes2_c268 73.203 73.203 -73.203 -2.576 -5.21E-05 -2.558 -5.645 1.66E-08 1.03E-06 5.40E-04 calponin transgelin /// 0003779 // actin binding /// 0031032 // actomyosin structure organization 119.661 624 "1,478" "1,947" 119.661 119.661 46.459 624 "1,119" "1,681" 46.459 46.459 ruditapes_c3448 10.767 10.767 -10.767 -2.576 -7.67E-06 -2.559 -2.165 0.03 0.362 1 kallikrein plasma (fletcher factor) 1 17.599 "1,131" 190 519 17.599 17.599 6.831 "1,131" 66 448 6.831 6.831 ruditapes_lrc25599 7.126 7.126 -7.126 -2.576 -5.08E-06 -2.559 -1.761 0.078 0.692 1 ppia protein /// 0016853 // isomerase activity 11.647 866 5 263 11.647 11.647 4.521 866 4 227 4.521 4.521 ruditapes_lrc21440 7.134 7.134 -7.134 -2.575 -5.08E-06 -2.558 -1.762 0.078 0.692 1 ribosomal protein l40 "/// 0006511 // ubiquitin-dependent protein catabolic process /// 0006355 // regulation of transcription, DNA-dependent /// 0005811 // lipid particle /// 0006950 // response to stress /// 0042254 // ribosome biogenesis /// 0005634 // nucleus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0006412 // translation /// 0006325 // chromatin organization /// 0003735 // structural constituent of ribosome /// 0006464 // protein modification process" 11.664 217 0 66 11.664 11.664 4.53 217 0 57 4.53 4.53 ruditapes_lrc34778 15.384 15.384 -15.384 -2.573 -1.10E-05 -2.556 -2.586 9.70E-03 0.151 1 activating transcription factor 4 /// 0016563 // transcription activator activity /// 0050811 // GABA receptor binding /// 0045944 // positive regulation of transcription from RNA polymerase II promoter /// 0003704 // specific RNA polymerase II transcription factor activity /// 0003677 // DNA binding /// 0005667 // transcription factor complex /// 0005737 // cytoplasm /// 0008022 // protein C-terminus binding /// 0006094 // gluconeogenesis 25.164 730 114 479 25.164 25.164 9.78 730 90 414 9.78 9.78 ruditapes_lrc32772 7.105 7.105 -7.105 -2.573 -5.06E-06 -2.556 -1.758 0.079 0.695 1 ribosomal protein l35a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome /// 0000049 // tRNA binding /// 0042273 // ribosomal large subunit biogenesis 11.621 462 0 140 11.621 11.621 4.517 462 0 121 4.517 4.517 ruditapes_c4254 7.232 7.232 -7.232 -2.567 -5.15E-06 -2.549 -1.771 0.077 0.684 1 prolyl-trna synthetase associated region 11.847 751 63 232 11.847 11.847 4.616 751 61 201 4.616 4.616 ruditapes_lrc39062 156.058 156.058 -156.058 -2.567 -1.11E-04 -2.549 -8.228 1.90E-16 2.49E-14 6.19E-12 ribosomal protein l32 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 255.67 384 139 "2,560" 255.67 255.67 99.612 384 137 "2,218" 99.612 99.612 ruditapes_c15407 10.733 10.733 -10.733 -2.564 -7.64E-06 -2.547 -2.157 0.031 0.368 1 mrna turnover protein 4 homolog /// 0042254 // ribosome biogenesis /// 0005634 // nucleus /// 0005840 // ribosome 17.595 837 384 384 17.595 17.595 6.861 837 333 333 6.861 6.861 ruditapes_lrc8076 11.328 11.328 -11.328 -2.564 -8.07E-06 -2.546 -2.216 0.027 0.329 1 trove domain protein /// 0040010 // positive regulation of growth rate /// 0003723 // RNA binding /// 0044424 // intracellular part 18.573 "1,464" 233 709 18.573 18.573 7.245 "1,464" 155 615 7.245 7.245 ruditapes_c12158 6.827 6.827 -6.827 -2.56 -4.86E-06 -2.543 -1.719 0.086 0.736 1 adenylate cyclase /// 0016020 // membrane /// 0016829 // lyase activity 11.203 469 137 137 11.203 11.203 4.376 469 119 119 4.376 4.376 ruditapes_c2527 19.624 19.624 -19.624 -2.56 -1.40E-05 -2.543 -2.914 3.57E-03 0.066 1 tandem repeat galectin /// 0005529 // sugar binding 32.203 680 389 571 32.203 32.203 12.579 680 307 496 12.579 12.579 ruditapes2_lrc5371 83.258 83.258 -83.258 -2.559 -5.93E-05 -2.542 -6.002 1.95E-09 1.38E-07 6.37E-05 nucleoside diphosphate kinase /// 0005524 // ATP binding /// 0007424 // open tracheal system development /// 0006468 // protein amino acid phosphorylation /// 0006183 // GTP biosynthetic process /// 0006241 // CTP biosynthetic process /// 0004550 // nucleoside diphosphate kinase activity /// 0006228 // UTP biosynthetic process 136.654 790 597 "2,815" 136.654 136.654 53.396 790 670 "2,446" 53.396 53.396 ruditapes2_c3305 51.936 51.936 -51.936 -2.556 -3.70E-05 -2.539 -4.738 2.16E-06 9.48E-05 0.07 protein 85.304 798 294 "1,775" 85.304 85.304 33.368 798 223 "1,544" 33.368 33.368 ruditapes_lrc33589 140.251 140.251 -140.251 -2.543 -9.99E-05 -2.526 -7.767 8.05E-15 9.34E-13 2.63E-10 beta 2c /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0042267 // natural killer cell mediated cytotoxicity /// 0005874 // microtubule /// 0006928 // cell motion /// 0051082 // unfolded protein binding /// 0042288 // MHC class I protein binding /// 0007018 // microtubule-based movement 231.134 856 "3,186" "5,159" 231.134 231.134 90.883 856 "2,048" "4,511" 90.883 90.883 ruditapes_c17608 "5,839.05" "5,839.05" "-5,839.05" -2.542 -4.16E-03 -2.525 -50.24 0 0 0 nadh dehydrogenase subunit 6 /// 0044464 // cell part "9,626.47" 558 "140,037" "140,065" "9,626.47" "9,626.47" "3,787.42" 558 "122,529" "122,545" "3,787.42" "3,787.42" ruditapes_c7540 7.764 7.764 -7.764 -2.538 -5.53E-06 -2.521 -1.826 0.068 0.632 1 bactericidal permeability increasing protein 12.811 "1,377" 409 460 12.811 12.811 5.047 "1,377" 353 403 5.047 5.047 ruditapes2_c60 6.328 6.328 -6.328 -2.536 -4.51E-06 -2.519 -1.648 0.099 0.803 1 nadh dehydrogenase 1 beta subcomplex 9 10.446 804 129 219 10.446 10.446 4.118 804 69 192 4.118 4.118 ruditapes2_c3215 8.351 8.351 -8.351 -2.534 -5.95E-06 -2.517 -1.892 0.059 0.574 1 nadh dehydrogenase flavoprotein 2 "/// 0006120 // mitochondrial electron transport, NADH to ubiquinone /// 0046872 // metal ion binding /// 0007399 // nervous system development /// 0008137 // NADH dehydrogenase (ubiquinone) activity /// 0005747 // mitochondrial respiratory chain complex I /// 0048738 // cardiac muscle tissue development /// 0009055 // electron carrier activity /// 0051536 // iron-sulfur cluster binding" 13.796 909 146 327 13.796 13.796 5.445 909 163 287 5.445 5.445 ruditapes_c7131 8.704 8.704 -8.704 -2.533 -6.20E-06 -2.516 -1.931 0.053 0.541 1 gamma-aminobutyric acid receptor-associated protein /// 0005794 // Golgi apparatus /// 0015031 // protein transport /// 0005875 // microtubule associated complex /// 0005886 // plasma membrane /// 0015629 // actin cytoskeleton /// 0005764 // lysosome /// 0005874 // microtubule /// 0008017 // microtubule binding /// 0000226 // microtubule cytoskeleton organization /// 0004872 // receptor activity 14.381 568 145 213 14.381 14.381 5.678 568 122 187 5.678 5.678 ruditapes2_lrc5397 235.955 235.955 -235.955 -2.526 -1.68E-04 -2.509 -10.043 9.87E-24 2.09E-21 3.22E-19 ribosomal protein l27 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 390.529 486 "1,310" "4,949" 390.529 390.529 154.573 486 914 "4,356" 154.573 154.573 ruditapes_c28442 17.772 17.772 -17.772 -2.524 -1.27E-05 -2.507 -2.755 5.87E-03 0.1 1 chaperonin containing subunit 4 /// 0005524 // ATP binding /// 0005811 // lipid particle /// 0042470 // melanosome /// 0051082 // unfolded protein binding /// 0006457 // protein folding 29.432 602 462 462 29.432 29.432 11.66 602 407 407 11.66 11.66 ruditapes_lrc32804 32.088 32.088 -32.088 -2.521 -2.29E-05 -2.504 -3.699 2.16E-04 6.12E-03 1 rna-binding expressed 53.184 318 63 441 53.184 53.184 21.096 318 82 389 21.096 21.096 ruditapes2_c6512 7.985 7.985 -7.985 -2.519 -5.69E-06 -2.502 -1.845 0.065 0.614 1 agrin 13.239 617 160 213 13.239 13.239 5.255 617 118 188 5.255 5.255 ruditapes2_c3343 35.19 35.19 -35.19 -2.518 -2.51E-05 -2.501 -3.872 1.08E-04 3.29E-03 1 calponin-like protein 58.37 "1,113" 82 "1,694" 58.37 58.37 23.18 "1,113" 106 "1,496" 23.18 23.18 ruditapes2_c134 8.627 8.627 -8.627 -2.513 -6.14E-06 -2.496 -1.915 0.055 0.555 1 trove domain member 2 14.329 "2,093" 266 782 14.329 14.329 5.702 "2,093" 265 692 5.702 5.702 ruditapes2_lrc3839 100.517 100.517 -100.517 -2.511 -7.16E-05 -2.494 -6.536 6.34E-11 5.22E-09 2.07E-06 histone /// 0005811 // lipid particle /// 0005634 // nucleus /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0005700 // polytene chromosome /// 0000786 // nucleosome 167.03 712 23 "3,101" 167.03 167.03 66.512 712 25 "2,746" 66.512 66.512 ruditapes2_c865 12.653 12.653 -12.653 -2.505 -9.01E-06 -2.488 -2.316 0.021 0.268 1 vacuolar atp synthase 16 kda proteolipid subunit "/// 0005774 // vacuolar membrane /// 0015986 // ATP synthesis coupled proton transport /// 0016021 // integral to membrane /// 0033179 // proton-transporting V-type ATPase, V0 domain /// 0015078 // hydrogen ion transmembrane transporter activity /// 0060059 // embryonic retina morphogenesis in camera-type eye" 21.059 "1,832" 891 "1,006" 21.059 21.059 8.406 "1,832" 707 893 8.406 8.406 ruditapes_c1528 91.345 91.345 -91.345 -2.496 -6.50E-05 -2.48 -6.212 5.22E-10 3.99E-08 1.70E-05 heat shock protein 90 /// 0005515 // protein binding /// 0009987 // cellular process /// 0005622 // intracellular 152.389 908 827 "3,608" 152.389 152.389 61.044 908 962 "3,214" 61.044 61.044 ruditapes_lrc36173 95.424 95.424 -95.424 -2.485 -6.80E-05 -2.468 -6.336 2.37E-10 1.83E-08 7.71E-06 60s ribosomal protein l7 /// 0007275 // multicellular organismal development /// 0040007 // growth /// 0015934 // large ribosomal subunit /// 0030528 // transcription regulator activity /// 0006412 // translation /// 0003735 // structural constituent of ribosome 159.674 532 93 "2,215" 159.674 159.674 64.25 532 79 "1,982" 64.25 64.25 ruditapes_c3586 8.246 8.246 -8.246 -2.483 -5.87E-06 -2.466 -1.861 0.063 0.6 1 nadh dehydrogenase 1 beta 19kda /// 0044444 // cytoplasmic part /// 0043231 // intracellular membrane-bounded organelle 13.806 825 25 297 13.806 13.806 5.56 825 21 266 5.56 5.56 ruditapes2_c5063 7.3 7.3 -7.3 -2.48 -5.20E-06 -2.463 -1.75 0.08 0.702 1 serine protease inhibitor 2 12.233 395 4 126 12.233 12.233 4.934 395 7 113 4.934 4.934 ruditapes_lrc35753 49.041 49.041 -49.041 -2.478 -3.49E-05 -2.461 -4.535 5.75E-06 2.33E-04 0.188 h+ transporting f1 atp synthase epsilon subunit "/// 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism" 82.223 382 42 819 82.223 82.223 33.182 382 67 735 33.182 33.182 ruditapes2_lrc4130 19.046 19.046 -19.046 -2.468 -1.36E-05 -2.451 -2.82 4.80E-03 0.085 1 mitochondrial atp synthase lipid binding protein precursor "/// 0006811 // ion transport /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain" 32.024 691 111 577 32.024 32.024 12.978 691 109 520 12.978 12.978 ruditapes_c527 418.936 418.936 -418.936 -2.462 -2.98E-04 -2.446 -13.216 7.09E-40 2.54E-37 2.31E-35 ribosomal protein l15 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0005829 // cytosol /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 705.456 790 "2,424" "14,532" 705.456 705.456 286.52 790 837 "13,125" 286.52 286.52 ruditapes_c9435 15.698 15.698 -15.698 -2.461 -1.12E-05 -2.444 -2.557 0.011 0.162 1 hairy and enhancer of split /// 0048667 // cell morphogenesis involved in neuron differentiation /// 0021983 // pituitary gland development /// 0042668 // auditory receptor cell fate determination /// 0008284 // positive regulation of cell proliferation /// 0005634 // nucleus /// 0001701 // in utero embryonic development /// 0021575 // hindbrain morphogenesis /// 0045608 // negative regulation of auditory receptor cell differentiation /// 0046982 // protein heterodimerization activity /// 0050768 // negative regulation of neurogenesis /// 0001889 // liver development /// 0003677 // DNA binding /// 0010552 // positive regulation of specific transcription from RNA polymerase II promoter /// 0021557 // oculomotor nerve development /// 0005737 // cytoplasm /// 0030324 // lung development /// 0016564 // transcription repressor activity /// 0021558 // trochlear nerve development /// 0060164 // regulation of timing of neuron differentiation /// 0048469 // cell maturation /// 0007155 // cell adhesion /// 0007219 // Notch signaling pathway /// 0010553 // negative regulation of specific transcription from RNA polymerase II promoter /// 0021555 // midbrain-hindbrain boundary morphogenesis /// 0030901 // midbrain development /// 0048635 // negative regulation of muscle development 26.443 "1,430" 499 986 26.443 26.443 10.745 "1,430" 632 891 10.745 10.745 ruditapes2_c32 50.234 50.234 -50.234 -2.46 -3.58E-05 -2.443 -4.573 4.80E-06 1.98E-04 0.156 atp synthase d chain /// 0005811 // lipid particle 84.648 888 639 "1,960" 84.648 84.648 34.414 888 602 "1,772" 34.414 34.414 ruditapes_s33824 6.945 6.945 -6.945 -2.459 -4.95E-06 -2.443 -1.7 0.089 0.754 1 ribosomal protein s17 /// 0006414 // translational elongation /// 0034101 // erythrocyte homeostasis /// 0006413 // translational initiation /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 11.704 308 0 94 11.704 11.704 4.759 308 0 85 4.759 4.759 ruditapes2_c932 30.809 30.809 -30.809 -2.455 -2.19E-05 -2.438 -3.578 3.46E-04 9.15E-03 1 tubulin alpha 3 /// 0005200 // structural constituent of cytoskeleton /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0005874 // microtubule /// 0000226 // microtubule cytoskeleton organization /// 0007018 // microtubule-based movement 51.983 979 467 "1,327" 51.983 51.983 21.174 979 617 "1,202" 21.174 21.174 ruditapes_c15181 6.841 6.841 -6.841 -2.444 -4.87E-06 -2.428 -1.682 0.092 0.772 1 phosphopyruvate hydratase /// 0044464 // cell part 11.578 477 144 144 11.578 11.578 4.736 477 131 131 4.736 4.736 ruditapes_lrc26308 7.757 7.757 -7.757 -2.439 -5.52E-06 -2.423 -1.79 0.073 0.667 1 ribosomal protein l35a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome /// 0000049 // tRNA binding /// 0042273 // ribosomal large subunit biogenesis 13.147 528 7 181 13.147 13.147 5.389 528 9 165 5.389 5.389 ruditapes_c691 9.961 9.961 -9.961 -2.434 -7.09E-06 -2.418 -2.026 0.043 0.461 1 spi1_craviserine protease inhibitor cvsi-1 precursor 16.908 499 181 220 16.908 16.908 6.947 499 91 201 6.947 6.947 ruditapes2_c295 7.156 7.156 -7.156 -2.419 -5.09E-06 -2.403 -1.712 0.087 0.742 1 phospholipase b1 /// 0016787 // hydrolase activity 12.199 896 285 285 12.199 12.199 5.043 896 262 262 5.043 5.043 ruditapes_c11596 160.505 160.505 -160.505 -2.416 -1.14E-04 -2.4 -8.103 5.37E-16 6.74E-14 1.75E-11 predicted protein [Nematostella vectensis] 273.821 736 "4,858" "5,255" 273.821 273.821 113.316 736 "4,403" "4,836" 113.316 113.316 ruditapes_c9410 7.01 7.01 -7.01 -2.41 -4.99E-06 -2.394 -1.691 0.091 0.764 1 PREDICTED: hypothetical protein [Strongylocentrotus purpuratus] 11.981 "1,242" 386 388 11.981 11.981 4.971 "1,242" 356 358 4.971 4.971 ruditapes_lrc15708 537.862 537.862 -537.862 -2.409 -3.83E-04 -2.393 -14.812 1.23E-49 5.26E-47 4.00E-45 beta-tubulin /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0042267 // natural killer cell mediated cytotoxicity /// 0005874 // microtubule /// 0006928 // cell motion /// 0051082 // unfolded protein binding /// 0042288 // MHC class I protein binding /// 0007018 // microtubule-based movement 919.609 715 "12,361" "17,145" 919.609 919.609 381.746 715 "8,998" "15,827" 381.746 381.746 ruditapes2_c1656 48.704 48.704 -48.704 -2.409 -3.47E-05 -2.392 -4.456 8.36E-06 3.30E-04 0.272 mitochondrial processing peptidase beta subunit "/// 0005811 // lipid particle /// 0006122 // mitochondrial electron transport, ubiquinol to cytochrome c /// 0046872 // metal ion binding /// 0005750 // mitochondrial respiratory chain complex III /// 0016485 // protein processing /// 0008121 // ubiquinol-cytochrome-c reductase activity /// 0017087 // mitochondrial processing peptidase complex" 83.279 "1,032" "2,241" "2,241" 83.279 83.279 34.575 "1,032" "2,069" "2,069" 34.575 34.575 ruditapes2_c92 56.167 56.167 -56.167 -2.401 -4.00E-05 -2.385 -4.777 1.78E-06 7.97E-05 0.058 ribosomal protein s16 /// 0005811 // lipid particle /// 0006414 // translational elongation /// 0005515 // protein binding /// 0042274 // ribosomal small subunit biogenesis /// 0000022 // mitotic spindle elongation /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 96.258 502 1 "1,260" 96.258 96.258 40.091 502 0 "1,167" 40.091 40.091 ruditapes_c2295 21.43 21.43 -21.43 -2.393 -1.53E-05 -2.377 -2.946 3.22E-03 0.061 1 ferritin /// 0055114 // oxidation reduction /// 0004322 // ferroxidase activity /// 0006826 // iron ion transport /// 0006879 // cellular iron ion homeostasis /// 0005737 // cytoplasm /// 0008199 // ferric iron binding 36.809 970 328 931 36.809 36.809 15.379 970 293 865 15.379 15.379 ruditapes2_c3295 51.058 51.058 -51.058 -2.392 -3.63E-05 -2.376 -4.546 5.46E-06 2.22E-04 0.178 cytochrome c oxidase subunit iv 87.729 546 403 "1,249" 87.729 87.729 36.671 546 410 "1,161" 36.671 36.671 ruditapes_c33910 9.545 9.545 -9.545 -2.385 -6.79E-06 -2.369 -1.963 0.05 0.511 1 histone h2a /// 0005694 // chromosome 16.436 896 173 384 16.436 16.436 6.891 896 183 358 6.891 6.891 ruditapes_lrc33602 55.897 55.897 -55.897 -2.382 -3.98E-05 -2.366 -4.747 2.07E-06 9.13E-05 0.067 aplp_locmi ame: full=apolipophorins contains: ame: full=apolipophorin-2 ame: full=apolipophorin ii ame: full=apolp-2 contains: ame: full=apolipophorin-1 ame: full=apolipophorin i ame: full=apolp-1 flags: precursor 96.334 670 113 "1,683" 96.334 96.334 40.437 670 93 "1,571" 40.437 40.437 ruditapes2_c3436 13.615 13.615 -13.615 -2.379 -9.69E-06 -2.363 -2.341 0.019 0.255 1 tetraspanin 3 /// 0016020 // membrane 23.486 774 376 474 23.486 23.486 9.871 774 345 443 9.871 9.871 ruditapes_lrc16425 12.767 12.767 -12.767 -2.375 -9.09E-06 -2.359 -2.265 0.024 0.297 1 ribosomal protein s2 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005654 // nucleoplasm /// 0048604 // fibroblast growth factor 3 binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0048602 // fibroblast growth factor 1 binding 22.049 654 27 376 22.049 22.049 9.282 654 24 352 9.282 9.282 ruditapes2_lrc3937 29.545 29.545 -29.545 -2.374 -2.10E-05 -2.358 -3.445 5.72E-04 0.014 1 s-adenosylhomocysteine hydrolase 51.048 "1,045" 66 "1,391" 51.048 51.048 21.504 "1,045" 132 "1,303" 21.504 21.504 ruditapes2_lrc5040 13.275 13.275 -13.275 -2.373 -9.45E-06 -2.357 -2.308 0.021 0.272 1 ferritin /// 0005488 // binding 22.944 931 51 557 22.944 22.944 9.669 931 54 522 9.669 9.669 ruditapes_c5534 6.65 6.65 -6.65 -2.37 -4.73E-06 -2.354 -1.633 0.103 0.82 1 eukaryotic translation initiation factor subunit e /// 0005634 // nucleus /// 0005515 // protein binding /// 0006412 // translation /// 0003743 // translation initiation factor activity /// 0005829 // cytosol 11.505 650 176 195 11.505 11.505 4.855 650 154 183 4.855 4.855 ruditapes2_c1376 12.822 12.822 -12.822 -2.366 -9.13E-06 -2.35 -2.265 0.024 0.297 1 alpha tubulin 22.212 461 211 267 22.212 22.212 9.39 461 216 251 9.39 9.39 ruditapes_lrc36178 7.329 7.329 -7.329 -2.363 -5.22E-06 -2.347 -1.711 0.087 0.742 1 mitochondrial atp synthase coupling factor 6 /// 0015992 // proton transport /// 0005753 // mitochondrial proton-transporting ATP synthase complex /// 0015078 // hydrogen ion transmembrane transporter activity 12.707 667 45 221 12.707 12.707 5.378 667 30 208 5.378 5.378 ruditapes_c2601 15.981 15.981 -15.981 -2.36 -1.14E-05 -2.344 -2.526 0.012 0.173 1 foot protein-4 variant-1 27.73 455 329 329 27.73 27.73 11.75 455 310 310 11.75 11.75 ruditapes_lrc33418 7.818 7.818 -7.818 -2.356 -5.56E-06 -2.34 -1.765 0.078 0.69 1 mitochondrial atp synthase coupling factor 6 /// 0015992 // proton transport /// 0003824 // catalytic activity /// 0005753 // mitochondrial proton-transporting ATP synthase complex /// 0015078 // hydrogen ion transmembrane transporter activity 13.584 655 27 232 13.584 13.584 5.766 655 12 219 5.766 5.766 ruditapes_c4090 12.383 12.383 -12.383 -2.349 -8.81E-06 -2.333 -2.218 0.027 0.327 1 axonemal dynein light chain p33 21.562 "1,366" 330 768 21.562 21.562 9.178 "1,366" 335 727 9.178 9.178 ruditapes2_c64 11.671 11.671 -11.671 -2.346 -8.31E-06 -2.331 -2.152 0.031 0.371 1 family with sequence similarity member a 20.338 577 257 306 20.338 20.338 8.668 577 210 290 8.668 8.668 ruditapes_s38880 12.743 12.743 -12.743 -2.345 -9.07E-06 -2.33 -2.248 0.025 0.307 1 elongation factor 1 beta 22.214 366 106 212 22.214 22.214 9.471 366 67 201 9.471 9.471 ruditapes_c11798 8.512 8.512 -8.512 -2.34 -6.06E-06 -2.324 -1.835 0.067 0.623 1 rna-binding partial 14.864 467 181 181 14.864 14.864 6.352 467 171 172 6.352 6.352 ruditapes2_c202 "3,385.74" "3,385.74" "-3,385.74" -2.338 -2.41E-03 -2.322 -36.641 7.68E-294 1.14E-290 2.51E-289 cytochrome c subunit ii /// 0046914 // transition metal ion binding /// 0022900 // electron transport chain /// 0005739 // mitochondrion /// 0016020 // membrane "5,916.35" 895 "103,389" "138,072" "5,916.35" "5,916.35" "2,530.62" 895 "110,865" "131,331" "2,530.62" "2,530.62" ruditapes2_c2382 9.308 9.308 -9.308 -2.338 -6.62E-06 -2.322 -1.918 0.055 0.552 1 orf msv234 hypthetical protein 16.266 580 245 246 16.266 16.266 6.958 580 228 234 6.958 6.958 ruditapes_c16036 9.134 9.134 -9.134 -2.337 -6.50E-06 -2.321 -1.899 0.058 0.567 1 fch domain only 2 15.967 795 168 331 15.967 15.967 6.833 795 216 315 6.833 6.833 ruditapes2_c255 407.885 407.885 -407.885 -2.33 -2.90E-04 -2.314 -12.674 8.22E-37 2.71E-34 2.68E-32 ribosomal protein l36a /// 0042221 // response to chemical stimulus /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 714.617 355 "6,615" "6,615" 714.617 714.617 306.731 355 "6,314" "6,314" 306.731 306.731 ruditapes_lrc34578 31.935 31.935 -31.935 -2.326 -2.27E-05 -2.311 -3.543 3.96E-04 0.01 1 ribosomal protein l5 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0008097 // 5S rRNA binding 56.013 621 3 907 56.013 56.013 24.077 621 3 867 24.077 24.077 ruditapes2_lrc4214 18.63 18.63 -18.63 -2.315 -1.33E-05 -2.299 -2.699 6.96E-03 0.116 1 atp binding 32.798 891 471 762 32.798 32.798 14.168 891 339 732 14.168 14.168 ruditapes2_lrc3296 74.038 74.038 -74.038 -2.303 -5.27E-05 -2.287 -5.365 8.08E-08 4.45E-06 2.64E-03 ribosomal protein s13 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 130.861 "1,014" 171 "3,460" 130.861 130.861 56.823 "1,014" 138 "3,341" 56.823 56.823 ruditapes2_c40 932.888 932.888 -932.888 -2.303 -6.64E-04 -2.287 -19.053 6.32E-81 4.04E-78 2.06E-76 ribosomal protein s28 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit "1,648.95" 309 "13,286" "13,286" "1,648.95" "1,648.95" 716.061 309 "12,830" "12,830" 716.061 716.061 ruditapes2_lrc5145 28.71 28.71 -28.71 -2.302 -2.04E-05 -2.286 -3.34 8.38E-04 0.02 1 ferritin /// 0006826 // iron ion transport /// 0016491 // oxidoreductase activity /// 0006879 // cellular iron ion homeostasis /// 0008199 // ferric iron binding 50.768 559 104 740 50.768 50.768 22.059 559 135 715 22.059 22.059 ruditapes_lrc38134 27.655 27.655 -27.655 -2.298 -1.97E-05 -2.283 -3.276 1.06E-03 0.024 1 eukaryotic translation elongation factor 1 beta 2 /// 0006414 // translational elongation /// 0005853 // eukaryotic translation elongation factor 1 complex /// 0003746 // translation elongation factor activity 48.954 217 30 277 48.954 48.954 21.299 217 22 268 21.299 21.299 ruditapes_lrc32454 278.926 278.926 -278.926 -2.298 -1.99E-04 -2.282 -10.402 2.42E-25 5.64E-23 7.89E-21 ribosomal protein l23 /// 0006414 // translational elongation /// 0006610 // ribosomal protein import into nucleus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0000022 // mitotic spindle elongation /// 0003735 // structural constituent of ribosome 493.826 462 241 "5,949" 493.826 493.826 214.9 462 130 "5,757" 214.9 214.9 ruditapes2_c137 10.89 10.89 -10.89 -2.288 -7.75E-06 -2.273 -2.05 0.04 0.443 1 mannose c type 1 19.345 "1,130" 570 570 19.345 19.345 8.455 "1,130" 554 554 8.455 8.455 ruditapes_c3869 172.993 172.993 -172.993 -2.279 -1.23E-04 -2.264 -8.155 3.50E-16 4.51E-14 1.14E-11 ribosomal protein l3 /// 0000022 // mitotic spindle elongation /// 0022626 // cytosolic ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 308.231 645 "1,209" "5,184" 308.231 308.231 135.239 645 "1,086" "5,058" 135.239 135.239 ruditapes_c7698 9.303 9.303 -9.303 -2.274 -6.62E-06 -2.259 -1.889 0.059 0.578 1 f5 8 type c domain protein 16.605 940 407 407 16.605 16.605 7.302 940 398 398 7.302 7.302 ruditapes2_c3511 7.678 7.678 -7.678 -2.271 -5.46E-06 -2.255 -1.714 0.086 0.74 1 s-crystallin sl11 (major lens polypeptide) 13.719 "1,079" 234 386 13.719 13.719 6.042 "1,079" 226 378 6.042 6.042 ruditapes_lrc35949 195.82 195.82 -195.82 -2.269 -1.39E-04 -2.254 -8.655 4.94E-18 7.26E-16 1.61E-13 60s ribosomal protein l6 /// 0030529 // ribonucleoprotein complex 350.136 385 278 "3,515" 350.136 350.136 154.316 385 324 "3,445" 154.316 154.316 ruditapes_c16615 36.979 36.979 -36.979 -2.266 -2.63E-05 -2.251 -3.758 1.71E-04 4.99E-03 1 endonuclease reverse transcriptase 66.186 682 "1,121" "1,177" 66.186 66.186 29.207 682 "1,079" "1,155" 29.207 29.207 ruditapes_c28591 41.35 41.35 -41.35 -2.266 -2.94E-05 -2.251 -3.974 7.08E-05 2.26E-03 1 glucosidase 2 subunit beta 74.013 585 657 "1,129" 74.013 74.013 32.664 585 631 "1,108" 32.664 32.664 ruditapes_lrc33733 82.484 82.484 -82.484 -2.265 -5.87E-05 -2.25 -5.612 2.00E-08 1.22E-06 6.53E-04 40s ribosomal protein s20 /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 147.665 508 318 "1,956" 147.665 147.665 65.181 508 200 "1,920" 65.181 65.181 ruditapes_lrc33994 270.674 270.674 -270.674 -2.264 -1.93E-04 -2.249 -10.164 2.87E-24 6.19E-22 9.34E-20 small subunit ribosomal protein 25 /// 0005840 // ribosome 484.751 450 "1,002" "5,688" 484.751 484.751 214.077 450 489 "5,586" 214.077 214.077 ruditapes2_c1677 30.862 30.862 -30.862 -2.263 -2.20E-05 -2.248 -3.431 6.02E-04 0.015 1 radial spokehead-like 3 55.287 "1,028" "1,482" "1,482" 55.287 55.287 24.426 "1,028" "1,456" "1,456" 24.426 24.426 ruditapes_lrc36525 15.384 15.384 -15.384 -2.26 -1.09E-05 -2.245 -2.42 0.016 0.216 1 guanine nucleotide binding protein beta polypeptide 2-like 1 /// 0019903 // protein phosphatase binding /// 0043025 // cell soma /// 0005737 // cytoplasm /// 0005102 // receptor binding /// 0007165 // signal transduction 27.592 606 73 436 27.592 27.592 12.209 606 42 429 12.209 12.209 ruditapes2_c3707 25.715 25.715 -25.715 -2.258 -1.83E-05 -2.243 -3.127 1.76E-03 0.037 1 glutathione peroxidase 3 /// 0005615 // extracellular space /// 0042744 // hydrogen peroxide catabolic process /// 0008430 // selenium binding /// 0008134 // transcription factor binding /// 0006982 // response to lipid hydroperoxide /// 0004602 // glutathione peroxidase activity /// 0051289 // protein homotetramerization 46.16 717 367 863 46.16 46.16 20.445 717 291 850 20.445 20.445 ruditapes2_c1190 124.138 124.138 -124.138 -2.255 -8.83E-05 -2.24 -6.867 6.55E-12 5.81E-10 2.14E-07 elongation factor 1-beta 223.044 804 "1,487" "4,676" 223.044 223.044 98.906 804 "1,118" "4,611" 98.906 98.906 ruditapes_lrc15185 50.239 50.239 -50.239 -2.253 -3.57E-05 -2.237 -4.366 1.27E-05 4.77E-04 0.413 ribosomal protein l17 /// 0006414 // translational elongation /// 0015934 // large ribosomal subunit /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 90.35 798 226 "1,880" 90.35 90.35 40.11 798 148 "1,856" 40.11 40.11 ruditapes_lrc33839 39.926 39.926 -39.926 -2.241 -2.84E-05 -2.226 -3.881 1.04E-04 3.18E-03 1 h3 histone family 3a /// 0001740 // Barr body /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0000786 // nucleosome 72.085 673 35 "1,265" 72.085 72.085 32.16 673 49 "1,255" 32.16 32.16 ruditapes_lrc7516 172.802 172.802 -172.802 -2.233 -1.23E-04 -2.218 -8.058 7.77E-16 9.67E-14 2.53E-11 laminin receptor 1 /// 0005624 // membrane fraction /// 0043236 // laminin binding /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0004872 // receptor activity 312.911 829 838 "6,764" 312.911 312.911 140.109 829 737 "6,735" 140.109 140.109 ruditapes_lrc32549 24.396 24.396 -24.396 -2.231 -1.74E-05 -2.216 -3.026 2.48E-03 0.049 1 ribosomal protein l26e 44.211 517 2 596 44.211 44.211 19.814 517 3 594 19.814 19.814 ruditapes2_lrc4096 15.178 15.178 -15.178 -2.228 -1.08E-05 -2.213 -2.384 0.017 0.233 1 mgc89694 protein /// 0006633 // fatty acid biosynthetic process /// 0000036 // acyl carrier activity /// 0031177 // phosphopantetheine binding /// 0048037 // cofactor binding 27.54 784 71 563 27.54 27.54 12.362 784 85 562 12.362 12.362 ruditapes2_c3306 72.889 72.889 -72.889 -2.226 -5.19E-05 -2.211 -5.223 1.76E-07 9.13E-06 5.74E-03 calponin-like protein 132.341 854 508 "2,947" 132.341 132.341 59.451 854 445 "2,944" 59.451 59.451 ruditapes_s38725 11.977 11.977 -11.977 -2.224 -8.52E-06 -2.209 -2.116 0.034 0.397 1 40s ribosomal protein s20 /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 21.764 474 56 269 21.764 21.764 9.787 474 40 269 9.787 9.787 ruditapes2_lrc4902 29.026 29.026 -29.026 -2.224 -2.07E-05 -2.209 -3.294 9.88E-04 0.023 1 ribosomal protein l11 /// 0006414 // translational elongation /// 0006605 // protein targeting /// 0005730 // nucleolus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development /// 0042273 // ribosomal large subunit biogenesis 52.745 738 83 "1,015" 52.745 52.745 23.719 738 44 "1,015" 23.719 23.719 ruditapes_lrc33726 14.757 14.757 -14.757 -2.218 -1.05E-05 -2.203 -2.345 0.019 0.253 1 ribosomal protein s13 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0003729 // mRNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0033119 // negative regulation of RNA splicing 26.874 538 0 377 26.874 26.874 12.117 538 0 378 12.117 12.117 ruditapes2_c1059 11.382 11.382 -11.382 -2.214 -8.10E-06 -2.199 -2.057 0.04 0.438 1 prolyl-trna synthetase associated protein 20.761 798 127 432 20.761 20.761 9.379 798 147 434 9.379 9.379 ruditapes_c14324 8.506 8.506 -8.506 -2.212 -6.05E-06 -2.197 -1.778 0.075 0.679 1 purple acid 15.525 457 152 185 15.525 15.525 7.019 457 151 186 7.019 7.019 ruditapes2_c2237 12.572 12.572 -12.572 -2.208 -8.94E-06 -2.193 -2.159 0.031 0.366 1 docking protein 3 22.978 943 565 565 22.978 22.978 10.406 943 569 569 10.406 10.406 ruditapes2_lrc4859 22.342 22.342 -22.342 -2.207 -1.59E-05 -2.192 -2.877 4.01E-03 0.073 1 isoform b 40.849 875 26 932 40.849 40.849 18.507 875 31 939 18.507 18.507 ruditapes2_lrc5088 291.312 291.312 -291.312 -2.201 -2.07E-04 -2.186 -10.375 3.22E-25 7.46E-23 1.05E-20 ribosomal protein l13 /// 0006414 // translational elongation /// 0051726 // regulation of cell cycle /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit 533.868 820 "1,663" "11,415" 533.868 533.868 242.555 820 556 "11,533" 242.555 242.555 ruditapes2_c121 10.09 10.09 -10.09 -2.197 -7.18E-06 -2.182 -1.929 0.054 0.542 1 tropomyosin 18.518 "2,218" 89 "1,071" 18.518 18.518 8.428 "2,218" 107 "1,084" 8.428 8.428 ruditapes_c4265 49.456 49.456 -49.456 -2.185 -3.52E-05 -2.17 -4.256 2.09E-05 7.47E-04 0.68 heat shock protein 90 /// 0005524 // ATP binding /// 0006950 // response to stress /// 0030235 // nitric-oxide synthase regulator activity /// 0045429 // positive regulation of nitric oxide biosynthetic process /// 0005737 // cytoplasm /// 0030911 // TPR domain binding /// 0051082 // unfolded protein binding /// 0006457 // protein folding 91.204 751 424 "1,786" 91.204 91.204 41.748 751 613 "1,818" 41.748 41.748 ruditapes_s39352 22.021 22.021 -22.021 -2.183 -1.57E-05 -2.168 -2.838 4.54E-03 0.081 1 60s ribosomal protein l9 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 40.639 352 0 373 40.639 40.639 18.618 352 1 380 18.618 18.618 ruditapes_c7870 9.576 9.576 -9.576 -2.177 -6.81E-06 -2.162 -1.868 0.062 0.594 1 pten induced kinase 1 /// 0005524 // ATP binding /// 0006950 // response to stress /// 0005739 // mitochondrion /// 0006468 // protein amino acid phosphorylation /// 0004674 // protein serine/threonine kinase activity /// 0000287 // magnesium ion binding /// 0007243 // protein kinase cascade 17.714 "1,102" 483 509 17.714 17.714 8.138 "1,102" 509 520 8.138 8.138 ruditapes_lrc33393 62.544 62.544 -62.544 -2.164 -4.45E-05 -2.149 -4.758 1.96E-06 8.69E-05 0.064 ribosomal protein l38 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development 116.297 308 77 934 116.297 116.297 53.753 308 53 960 53.753 53.753 ruditapes2_lrc3596 212.128 212.128 -212.128 -2.156 -1.51E-04 -2.141 -8.745 2.23E-18 3.32E-16 7.28E-14 tubulin alpha-3 /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0005874 // microtubule /// 0007018 // microtubule-based movement 395.635 860 "3,705" "8,872" 395.635 395.635 183.507 860 "3,063" "9,151" 183.507 183.507 ruditapes2_lrc5258 8.092 8.092 -8.092 -2.154 -5.75E-06 -2.139 -1.707 0.088 0.747 1 ribosomal protein l8 /// 0006414 // translational elongation /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0003735 // structural constituent of ribosome 15.105 391 0 154 15.105 15.105 7.013 391 0 159 7.013 7.013 ruditapes2_lrc4212 87.498 87.498 -87.498 -2.151 -6.22E-05 -2.137 -5.608 2.04E-08 1.24E-06 6.66E-04 40s ribosomal protein s17 /// 0005622 // intracellular 163.505 577 159 "2,460" 163.505 163.505 76.007 577 148 "2,543" 76.007 76.007 ruditapes2_c184 8.319 8.319 -8.319 -2.15 -5.92E-06 -2.135 -1.729 0.084 0.726 1 xylose isomerase /// 0046872 // metal ion binding /// 0006098 // pentose-phosphate shunt /// 0042732 // D-xylose metabolic process /// 0009045 // xylose isomerase activity 15.554 "1,075" 409 436 15.554 15.554 7.235 "1,075" 418 451 7.235 7.235 ruditapes2_c315 11.083 11.083 -11.083 -2.145 -7.88E-06 -2.13 -1.992 0.046 0.488 1 prefoldin subunit 2 /// 0016272 // prefoldin complex /// 0051082 // unfolded protein binding /// 0006457 // protein folding 20.765 953 401 516 20.765 20.765 9.682 953 436 535 9.682 9.682 ruditapes_lrc33374 16.501 16.501 -16.501 -2.141 -1.17E-05 -2.127 -2.428 0.015 0.213 1 ribosomal protein s6 /// 0005811 // lipid particle /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0006955 // immune response 30.962 545 8 440 30.962 30.962 14.461 545 13 457 14.461 14.461 ruditapes2_c1164 13.266 13.266 -13.266 -2.132 -9.43E-06 -2.118 -2.172 0.03 0.358 1 novel protein 24.985 571 361 372 24.985 24.985 11.719 571 368 388 11.719 11.719 ruditapes_c401 7.989 7.989 -7.989 -2.125 -5.68E-06 -2.11 -1.682 0.093 0.772 1 type alpha 1 /// 0005198 // structural molecule activity /// 0005578 // proteinaceous extracellular matrix 15.091 709 47 279 15.091 15.091 7.103 709 60 292 7.103 7.103 ruditapes2_c4603 147.554 147.554 -147.554 -2.124 -1.05E-04 -2.11 -7.227 4.92E-13 4.91E-11 1.61E-08 ribosomal protein l6 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 278.805 678 440 "4,929" 278.805 278.805 131.251 678 483 "5,160" 131.251 131.251 ruditapes_c2464 8.445 8.445 -8.445 -2.116 -6.00E-06 -2.102 -1.725 0.085 0.73 1 ferritin /// 0055114 // oxidation reduction /// 0004322 // ferroxidase activity /// 0006826 // iron ion transport /// 0006879 // cellular iron ion homeostasis /// 0005737 // cytoplasm /// 0008199 // ferric iron binding 16.011 800 85 334 16.011 16.011 7.567 800 73 351 7.567 7.567 ruditapes_lrc38640 22.392 22.392 -22.392 -2.114 -1.59E-05 -2.1 -2.807 5.00E-03 0.088 1 ependymin related protein-1 precursor 42.492 713 79 790 42.492 42.492 20.1 713 56 831 20.1 20.1 ruditapes2_c5480 83.351 83.351 -83.351 -2.114 -5.93E-05 -2.1 -5.416 6.11E-08 3.42E-06 1.99E-03 ribosomal protein l26 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0042273 // ribosomal large subunit biogenesis 158.176 490 283 "2,021" 158.176 158.176 74.825 490 273 "2,126" 74.825 74.825 ruditapes2_lrc4797 467.118 467.118 -467.118 -2.113 -3.32E-04 -2.099 -12.821 1.26E-37 4.33E-35 4.11E-33 ribosomal protein s7 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 886.719 626 784 "14,474" 886.719 886.719 419.601 626 542 "15,231" 419.601 419.601 ruditapes_c2021 14.625 14.625 -14.625 -2.112 -1.04E-05 -2.098 -2.267 0.023 0.296 1 mgc84531 protein 27.772 "1,258" 703 911 27.772 27.772 13.147 "1,258" 660 959 13.147 13.147 ruditapes_lrc32328 135.005 135.005 -135.005 -2.105 -9.60E-05 -2.091 -6.874 6.23E-12 5.54E-10 2.03E-07 ribosomal protein l6 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 257.181 711 290 "4,768" 257.181 257.181 122.176 711 324 "5,037" 122.176 122.176 ruditapes_c422 228.687 228.687 -228.687 -2.104 -1.63E-04 -2.089 -8.944 3.77E-19 5.92E-17 1.23E-14 ribosomal protein l35 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0003729 // mRNA binding /// 0022625 // cytosolic large ribosomal subunit /// 0003735 // structural constituent of ribosome 435.901 456 827 "5,183" 435.901 435.901 207.214 456 "1,126" "5,479" 207.214 207.214 ruditapes2_c517 9.2 9.2 -9.2 -2.1 -6.54E-06 -2.086 -1.792 0.073 0.666 1 complement component 17.561 594 201 272 17.561 17.561 8.362 594 213 288 8.362 8.362 ruditapes_c11801 8.644 8.644 -8.644 -2.097 -6.15E-06 -2.083 -1.735 0.083 0.72 1 dna polymerase iii alpha subunit 16.524 499 140 215 16.524 16.524 7.88 499 153 228 7.88 7.88 ruditapes2_c3200 15.444 15.444 -15.444 -2.093 -1.10E-05 -2.079 -2.317 0.021 0.268 1 prolyl-trna synthetase associated region 29.569 "1,249" 455 963 29.569 29.569 14.125 "1,249" 447 "1,023" 14.125 14.125 ruditapes_lrc8151 50.117 50.117 -50.117 -2.089 -3.56E-05 -2.075 -4.168 3.07E-05 1.06E-03 1 guanine nucleotide binding protein (g protein) beta polypeptide 2-like 1 /// 0019903 // protein phosphatase binding /// 0043025 // cell soma /// 0005737 // cytoplasm 96.124 930 272 "2,331" 96.124 96.124 46.007 930 240 "2,481" 46.007 46.007 ruditapes2_lrc6026 17.633 17.633 -17.633 -2.088 -1.25E-05 -2.074 -2.472 0.013 0.194 1 ependymin related protein 1 precursor 33.839 663 34 585 33.839 33.839 16.205 663 28 623 16.205 16.205 ruditapes_lrc35676 73.365 73.365 -73.365 -2.079 -5.22E-05 -2.065 -5.027 4.97E-07 2.40E-05 0.016 beta 2c /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0042267 // natural killer cell mediated cytotoxicity /// 0005874 // microtubule /// 0006928 // cell motion /// 0051082 // unfolded protein binding /// 0042288 // MHC class I protein binding /// 0007018 // microtubule-based movement 141.367 615 "1,533" "2,267" 141.367 141.367 68.002 615 "1,336" "2,425" 68.002 68.002 ruditapes_c3475 37.526 37.526 -37.526 -2.079 -2.67E-05 -2.065 -3.596 3.23E-04 8.66E-03 1 heterogeneous nuclear ribonucleoprotein d-like /// 0003676 // nucleic acid binding /// 0010467 // gene expression /// 0016070 // RNA metabolic process /// 0044424 // intracellular part 72.3 488 664 920 72.3 72.3 34.774 488 739 984 34.774 34.774 ruditapes_lrc33883 41.523 41.523 -41.523 -2.062 -2.95E-05 -2.048 -3.763 1.68E-04 4.90E-03 1 40s ribosomal protein s27 /// 0006414 // translational elongation /// 0008283 // cell proliferation /// 0005634 // nucleus /// 0005515 // protein binding /// 0003677 // DNA binding /// 0008270 // zinc ion binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 80.612 559 201 "1,175" 80.612 80.612 39.088 559 192 "1,267" 39.088 39.088 ruditapes_lrc33658 13.772 13.772 -13.772 -2.059 -9.79E-06 -2.045 -2.165 0.03 0.363 1 serine protease inhibitor 2 26.78 411 96 287 26.78 26.78 13.008 411 75 310 13.008 13.008 ruditapes2_c4177 12.985 12.985 -12.985 -2.058 -9.23E-06 -2.044 -2.101 0.036 0.407 1 tubulin polymerization-promoting protein family member 3 /// 0002119 // nematode larval development /// 0000003 // reproduction 25.256 "1,151" 97 758 25.256 25.256 12.271 "1,151" 141 819 12.271 12.271 ruditapes2_lrc4789 43.684 43.684 -43.684 -2.054 -3.11E-05 -2.04 -3.849 1.19E-04 3.60E-03 1 apolipophorin precursor protein 85.136 882 332 "1,958" 85.136 85.136 41.452 882 452 "2,120" 41.452 41.452 ruditapes2_c259 345.166 345.166 -345.166 -2.046 -2.45E-04 -2.033 -10.796 3.60E-27 9.09E-25 1.17E-22 ribosomal protein s18 /// 0007275 // multicellular organismal development /// 0006414 // translational elongation /// 0051726 // regulation of cell cycle /// 0019843 // rRNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0006417 // regulation of translation 675.003 684 734 "12,039" 675.003 675.003 329.838 684 229 "13,082" 329.838 329.838 ruditapes2_lrc3482 18.979 18.979 -18.979 -2.042 -1.35E-05 -2.028 -2.527 0.012 0.172 1 atp synthase subunit b 37.201 "1,201" 228 "1,165" 37.201 37.201 18.222 "1,201" 231 "1,269" 18.222 18.222 ruditapes2_c427 51.081 51.081 -51.081 -2.042 -3.63E-05 -2.028 -4.146 3.38E-05 1.15E-03 1 psmd1 protein /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005515 // protein binding /// 0005838 // proteasome regulatory particle 100.109 "1,273" "3,323" "3,323" 100.109 100.109 49.028 "1,273" "3,619" "3,619" 49.028 49.028 ruditapes_c10251 19.8 19.8 -19.8 -2.041 -1.41E-05 -2.027 -2.581 9.86E-03 0.153 1 mgc79762 protein 38.818 574 562 581 38.818 38.818 19.018 574 601 633 19.018 19.018 ruditapes2_c258 34.973 34.973 -34.973 -2.038 -2.49E-05 -2.025 -3.427 6.10E-04 0.015 1 heat shock protein 90 /// 0005524 // ATP binding /// 0006950 // response to stress /// 0030235 // nitric-oxide synthase regulator activity /// 0045429 // positive regulation of nitric oxide biosynthetic process /// 0030911 // TPR domain binding /// 0051082 // unfolded protein binding /// 0006457 // protein folding 68.651 848 704 "1,518" 68.651 68.651 33.678 848 858 "1,656" 33.678 33.678 ruditapes2_c373 50.255 50.255 -50.255 -2.034 -3.57E-05 -2.02 -4.102 4.10E-05 1.37E-03 1 cytochrome somatic "/// 0042743 // hydrogen peroxide metabolic process /// 0005759 // mitochondrial matrix /// 0006810 // transport /// 0006309 // DNA fragmentation involved in apoptosis /// 0005634 // nucleus /// 0043065 // positive regulation of apoptosis /// 0006123 // mitochondrial electron transport, cytochrome c to oxygen /// 0020037 // heme binding /// 0005746 // mitochondrial respiratory chain /// 0005625 // soluble fraction /// 0006979 // response to oxidative stress /// 0005829 // cytosol /// 0008635 // activation of caspase activity by cytochrome c /// 0045155 // electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity /// 0008289 // lipid binding" 98.879 792 329 "2,042" 98.879 98.879 48.623 792 383 "2,233" 48.623 48.623 ruditapes_s37429 17.904 17.904 -17.904 -2.028 -1.27E-05 -2.014 -2.443 0.015 0.206 1 alpha 3 type vi collagen isoform 1 precursor 35.325 393 80 362 35.325 35.325 17.421 393 154 397 17.421 17.421 ruditapes_lrc32788 331.075 331.075 -331.075 -2.024 -2.35E-04 -2.01 -10.496 8.99E-26 2.12E-23 2.93E-21 ribosomal protein l26 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0042273 // ribosomal large subunit biogenesis 654.384 522 "1,158" "8,907" 654.384 654.384 323.308 522 "1,525" "9,786" 323.308 323.308 ruditapes_lrc32136 8.946 8.946 -8.946 -2.023 -6.36E-06 -2.009 -1.725 0.085 0.73 1 AF339450_1hillarin [Hirudo medicinalis] 17.689 "1,071" 72 494 17.689 17.689 8.744 "1,071" 37 543 8.744 8.744 ruditapes2_c857 47.967 47.967 -47.967 -2.023 -3.41E-05 -2.01 -3.994 6.50E-05 2.09E-03 1 thioredoxin /// 0009987 // cellular process 94.837 "1,421" "1,191" "3,514" 94.837 94.837 46.871 "1,421" "1,448" "3,862" 46.871 46.871 ruditapes_lrc35548 26.403 26.403 -26.403 -2.02 -1.88E-05 -2.007 -2.96 3.08E-03 0.059 1 elongation factor 1 delta /// 0006412 // translation 52.283 779 101 "1,062" 52.283 52.283 25.88 779 125 "1,169" 25.88 25.88 ruditapes2_lrc4161 35.753 35.753 -35.753 -2.02 -2.54E-05 -2.006 -3.444 5.73E-04 0.014 1 tyb_aplca ame: full=thymosin beta ame: full=beta-thymosin 70.81 944 10 "1,743" 70.81 70.81 35.058 944 5 "1,919" 35.058 35.058 ruditapes_c2257 75.686 75.686 -75.686 -2.019 -5.38E-05 -2.005 -5.009 5.46E-07 2.63E-05 0.018 cytochrome c oxidase subunit ii /// 0006810 // transport /// 0005507 // copper ion binding /// 0004129 // cytochrome-c oxidase activity /// 0020037 // heme binding /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane /// 0009055 // electron carrier activity /// 0022904 // respiratory electron transport chain 149.97 514 "1,274" "2,010" 149.97 149.97 74.284 514 "1,695" "2,214" 74.284 74.284 ruditapes2_lrc4394 266.24 266.24 -266.24 -2.012 -1.89E-04 -1.999 -9.376 6.87E-21 1.24E-18 2.24E-16 ribosomal protein l13a /// 0015934 // large ribosomal subunit /// 0006412 // translation /// 0003735 // structural constituent of ribosome 529.238 660 "3,060" "9,108" 529.238 529.238 262.998 660 "1,675" "10,065" 262.998 262.998 ruditapes2_c1342 8.761 8.761 -8.761 -2.007 -6.22E-06 -1.993 -1.697 0.09 0.757 1 "PREDICTED: similar to predicted protein, partial [Hydra magnipapillata]" 17.465 426 46 194 17.465 17.465 8.704 426 61 215 8.704 8.704 ruditapes2_lrc3145 275.716 275.716 -275.716 -2.004 -1.96E-04 -1.991 -9.515 1.81E-21 3.36E-19 5.91E-17 alpha 8 like 4 550.254 977 "6,453" "14,018" 550.254 550.254 274.538 977 "5,405" "15,553" 274.538 274.538 ruditapes_c486 25.027 25.027 -25.027 -2.002 -1.78E-05 -1.988 -2.864 4.18E-03 0.075 1 eukaryotic translation initiation factor 5a /// 0006413 // translational initiation /// 0003743 // translation initiation factor activity 50.006 "1,405" 209 "1,832" 50.006 50.006 24.979 "1,405" 202 "2,035" 24.979 24.979 ruditapes2_c3301 10.577 10.577 -10.577 -2.002 -7.51E-06 -1.989 -1.862 0.063 0.6 1 translocon-associated protein subunit gamma /// 0005789 // endoplasmic reticulum membrane /// 0005488 // binding /// 0016021 // integral to membrane 21.127 "1,051" 240 579 21.127 21.127 10.551 "1,051" 227 643 10.551 10.551 ruditapes2_lrc3447 112.821 112.821 -112.821 -1.991 -8.02E-05 -1.977 -6.058 1.38E-09 1.00E-07 4.50E-05 ribosomal protein l7 /// 0015934 // large ribosomal subunit /// 0030528 // transcription regulator activity /// 0006412 // translation /// 0003735 // structural constituent of ribosome 226.721 "1,100" 316 "6,503" 226.721 226.721 113.9 "1,100" 358 "7,265" 113.9 113.9 ruditapes_lrc32869 35.244 35.244 -35.244 -1.987 -2.50E-05 -1.974 -3.381 7.21E-04 0.017 1 ribosomal protein l18a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 70.955 594 38 "1,099" 70.955 70.955 35.711 594 10 "1,230" 35.711 35.711 ruditapes_lrc32531 11.983 11.983 -11.983 -1.985 -8.51E-06 -1.972 -1.97 0.049 0.504 1 cytochrome c oxidase subunit via polypeptide 1 /// 0016491 // oxidoreductase activity /// 0005743 // mitochondrial inner membrane /// 0008152 // metabolic process 24.147 621 47 391 24.147 24.147 12.164 621 34 438 12.164 12.164 ruditapes_lrc39587 8.775 8.775 -8.775 -1.984 -6.23E-06 -1.97 -1.685 0.092 0.769 1 set translocation (myeloid leukemia-associated) b /// 0048471 // perinuclear region of cytoplasm /// 0004864 // phosphoprotein phosphatase inhibitor activity /// 0006337 // nucleosome disassembly /// 0005634 // nucleus /// 0006334 // nucleosome assembly /// 0035067 // negative regulation of histone acetylation /// 0005783 // endoplasmic reticulum /// 0008601 // protein phosphatase type 2A regulator activity /// 0006260 // DNA replication /// 0006913 // nucleocytoplasmic transport /// 0042393 // histone binding 17.694 466 110 215 17.694 17.694 8.919 466 115 241 8.919 8.919 ruditapes_lrc34496 125.577 125.577 -125.577 -1.978 -8.92E-05 -1.965 -6.364 1.97E-10 1.54E-08 6.41E-06 ribosomal protein s11 /// 0005840 // ribosome /// 0019843 // rRNA binding /// 0006412 // translation /// 0003735 // structural constituent of ribosome 253.925 520 112 "3,443" 253.925 253.925 128.348 520 64 "3,870" 128.348 128.348 ruditapes_c3931 59.294 59.294 -59.294 -1.971 -4.21E-05 -1.958 -4.362 1.29E-05 4.84E-04 0.421 heat shock protein 90 /// 0005524 // ATP binding /// 0006950 // response to stress /// 0030235 // nitric-oxide synthase regulator activity /// 0045429 // positive regulation of nitric oxide biosynthetic process /// 0005737 // cytoplasm /// 0030911 // TPR domain binding /// 0051082 // unfolded protein binding /// 0006457 // protein folding 120.35 731 361 "2,294" 120.35 120.35 61.056 731 617 "2,588" 61.056 61.056 ruditapes2_lrc4739 10.109 10.109 -10.109 -1.971 -7.18E-06 -1.958 -1.801 0.072 0.656 1 ribosomal protein s7 /// 0006414 // translational elongation /// 0051726 // regulation of cell cycle /// 0005730 // nucleolus /// 0005515 // protein binding /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0022627 // cytosolic small ribosomal subunit 20.521 641 0 343 20.521 20.521 10.412 641 1 387 10.412 10.412 ruditapes_s38992 38.646 38.646 -38.646 -1.97 -2.75E-05 -1.957 -3.52 4.32E-04 0.011 1 beta-actin 78.485 129 148 264 78.485 78.485 39.839 129 109 298 39.839 39.839 ruditapes_c15268 11.324 11.324 -11.324 -1.97 -8.04E-06 -1.957 -1.905 0.057 0.563 1 sperm flagellar 2 22.997 557 334 334 22.997 22.997 11.673 557 377 377 11.673 11.673 ruditapes2_lrc2615 718.112 718.112 -718.112 -1.965 -5.10E-04 -1.952 -15.154 7.16E-52 3.16E-49 2.34E-47 ribosomal protein s24 /// 0006414 // translational elongation /// 0005634 // nucleus /// 0034101 // erythrocyte homeostasis /// 0042274 // ribosomal small subunit biogenesis /// 0031369 // translation initiation factor binding /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit "1,461.97" 511 "1,237" "19,480" "1,461.97" "1,461.97" 743.862 511 625 "22,041" 743.862 743.862 ruditapes2_lrc3869 268.95 268.95 -268.95 -1.964 -1.91E-04 -1.951 -9.267 1.91E-20 3.36E-18 6.22E-16 ribosomal protein l7 547.901 914 "1,183" "13,058" 547.901 547.901 278.951 914 979 "14,784" 278.951 278.951 ruditapes_c27709 14.769 14.769 -14.769 -1.964 -1.05E-05 -1.951 -2.171 0.03 0.358 1 serine protease inhibitor 2 30.089 376 295 295 30.089 30.089 15.319 376 334 334 15.319 15.319 ruditapes2_c3823 15.898 15.898 -15.898 -1.96 -1.13E-05 -1.947 -2.249 0.024 0.307 1 malate dehydrogenase nad /// 0030060 // L-malate dehydrogenase activity /// 0055114 // oxidation reduction /// 0006108 // malate metabolic process /// 0006099 // tricarboxylic acid cycle /// 0005488 // binding /// 0006096 // glycolysis /// 0005737 // cytoplasm 32.458 755 16 639 32.458 32.458 16.56 755 35 725 16.56 16.56 ruditapes_c3537 33.993 33.993 -33.993 -1.954 -2.41E-05 -1.941 -3.282 1.03E-03 0.024 1 protein /// 0006810 // transport /// 0005216 // ion channel activity /// 0016020 // membrane 69.616 655 757 "1,189" 69.616 69.616 35.624 655 847 "1,353" 35.624 35.624 ruditapes_c7637 11.518 11.518 -11.518 -1.953 -8.18E-06 -1.94 -1.91 0.056 0.558 1 tektin 2 /// 0005856 // cytoskeleton /// 0016043 // cellular component organization /// 0042995 // cell projection /// 0006928 // cell motion 23.6 845 520 520 23.6 23.6 12.082 845 592 592 12.082 12.082 ruditapes2_c1073 8.792 8.792 -8.792 -1.944 -6.24E-06 -1.931 -1.663 0.096 0.788 1 h aca ribonucleoprotein complex subunit 2-like protein /// 0042254 // ribosome biogenesis /// 0003676 // nucleic acid binding /// 0044424 // intracellular part 18.1 767 263 362 18.1 18.1 9.309 767 311 414 9.309 9.309 ruditapes_lrc32626 28.22 28.22 -28.22 -1.941 -2.00E-05 -1.928 -2.976 2.92E-03 0.056 1 prostaglandin d synthase-like 58.212 782 61 "1,187" 58.212 58.212 29.993 782 115 "1,360" 29.993 29.993 ruditapes2_lrc3199 83.518 83.518 -83.518 -1.94 -5.93E-05 -1.927 -5.118 3.09E-07 1.54E-05 0.01 ribosomal protein s13 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0003729 // mRNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0033119 // negative regulation of RNA splicing 172.402 981 166 "4,410" 172.402 172.402 88.883 981 200 "5,056" 88.883 88.883 ruditapes2_lrc5444 95.432 95.432 -95.432 -1.939 -6.78E-05 -1.926 -5.47 4.51E-08 2.57E-06 1.47E-03 ribosomal protein l7a /// 0042788 // polysomal ribosome /// 0006414 // translational elongation /// 0042254 // ribosome biogenesis /// 0005624 // membrane fraction /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 197.06 990 139 "5,087" 197.06 197.06 101.628 990 315 "5,834" 101.628 101.628 ruditapes_lrc30423 43.39 43.39 -43.39 -1.935 -3.08E-05 -1.922 -3.683 2.31E-04 6.46E-03 1 receptor of activated kinase c 1 /// 0019903 // protein phosphatase binding /// 0043025 // cell soma /// 0005737 // cytoplasm 89.789 504 113 "1,180" 89.789 89.789 46.399 504 130 "1,356" 46.399 46.399 ruditapes_lrc35917 18.058 18.058 -18.058 -1.934 -1.28E-05 -1.92 -2.374 0.018 0.239 1 ribosomal protein l14 /// 0030529 // ribonucleoprotein complex 37.402 485 8 473 37.402 37.402 19.344 485 13 544 19.344 19.344 ruditapes_lrc34991 73.053 73.053 -73.053 -1.931 -5.19E-05 -1.918 -4.77 1.84E-06 8.24E-05 0.06 guanine nucleotide-binding protein subunit beta-2-like 1 /// 0019903 // protein phosphatase binding /// 0043025 // cell soma /// 0005737 // cytoplasm 151.551 435 183 "1,719" 151.551 151.551 78.498 435 235 "1,980" 78.498 78.498 ruditapes2_lrc4617 10.053 10.053 -10.053 -1.929 -7.14E-06 -1.916 -1.768 0.077 0.687 1 dynein cytoplasmic light peptide transcript variant 1 /// 0030286 // dynein complex /// 0016459 // myosin complex /// 0005634 // nucleus /// 0043186 // P granule /// 0005886 // plasma membrane /// 0005515 // protein binding /// 0005829 // cytosol /// 0005874 // microtubule /// 0003777 // microtubule motor activity /// 0007017 // microtubule-based process 20.874 553 39 301 20.874 20.874 10.821 553 39 347 10.821 10.821 ruditapes2_c5657 38.775 38.775 -38.775 -1.923 -2.75E-05 -1.91 -3.465 5.30E-04 0.013 1 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) /// 0006414 // translational elongation /// 0005515 // protein binding /// 0004871 // signal transducer activity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade /// 0005829 // cytosol /// 0005853 // eukaryotic translation elongation factor 1 complex 80.787 704 192 "1,483" 80.787 80.787 42.012 704 140 "1,715" 42.012 42.012 ruditapes_lrc33453 12.598 12.598 -12.598 -1.914 -8.95E-06 -1.902 -1.969 0.049 0.506 1 ribosomal protein l9 /// 0030529 // ribonucleoprotein complex 26.375 522 1 359 26.375 26.375 13.777 522 0 417 13.777 13.777 ruditapes2_lrc4529 26.198 26.198 -26.198 -1.908 -1.86E-05 -1.896 -2.833 4.62E-03 0.082 1 60s ribosomal protein l10a /// 0005811 // lipid particle /// 0044238 // primary metabolic process /// 0022625 // cytosolic large ribosomal subunit /// 0010467 // gene expression /// 0000022 // mitotic spindle elongation /// 0003735 // structural constituent of ribosome /// 0034960 // cellular biopolymer metabolic process 55.035 793 95 "1,138" 55.035 55.035 28.837 793 69 "1,326" 28.837 28.837 ruditapes2_c1512 8.732 8.732 -8.732 -1.894 -6.20E-06 -1.881 -1.626 0.104 0.827 1 sarcoplasmic calcium-binding protein /// 0005509 // calcium ion binding 18.497 989 54 477 18.497 18.497 9.765 989 99 560 9.765 9.765 ruditapes_c27781 14.585 14.585 -14.585 -1.892 -1.04E-05 -1.879 -2.1 0.036 0.408 1 2500003m10rik protein 30.935 693 517 559 30.935 30.935 16.35 693 617 657 16.35 16.35 ruditapes_c3502 188.307 188.307 -188.307 -1.89 -1.34E-04 -1.877 -7.539 4.75E-14 5.01E-12 1.55E-09 ribosomal protein l5 /// 0006414 // translational elongation /// 0005634 // nucleus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0008097 // 5S rRNA binding /// 0042273 // ribosomal large subunit biogenesis 400.003 "1,246" 963 "12,996" 400.003 400.003 211.696 "1,246" "1,393" "15,295" 211.696 211.696 ruditapes_lrc32628 19.21 19.21 -19.21 -1.888 -1.36E-05 -1.875 -2.406 0.016 0.222 1 cathepsin l 40.846 876 114 933 40.846 40.846 21.636 876 116 "1,099" 21.636 21.636 ruditapes2_c895 "11,310.42" "11,310.42" "-11,310.42" -1.883 -8.03E-03 -1.87 -58.686 0 0 0 cytochrome c oxidase subunit ii /// 0044464 // cell part "24,122.63" "1,443" "812,549" "907,652" "24,122.63" "24,122.63" "12,812.21" "1,443" "971,158" "1,072,033" "12,812.21" "12,812.21" ruditapes2_c4288 109.403 109.403 -109.403 -1.882 -7.77E-05 -1.869 -5.729 1.01E-08 6.59E-07 3.30E-04 large subunit ribosomal protein 30 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 233.43 438 22 "2,666" 233.43 233.43 124.028 438 28 "3,150" 124.028 124.028 ruditapes_lrc33749 205.158 205.158 -205.158 -1.878 -1.46E-04 -1.865 -7.832 4.81E-15 5.66E-13 1.57E-10 ribosomal protein l18a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 438.875 489 258 "5,596" 438.875 438.875 233.717 489 379 "6,627" 233.717 233.717 ruditapes2_lrc3943 9.001 9.001 -9.001 -1.877 -6.39E-06 -1.865 -1.64 0.101 0.811 1 ependymin related protein-1 precursor 19.261 669 4 336 19.261 19.261 10.26 669 7 398 10.26 10.26 ruditapes2_c1391 24.819 24.819 -24.819 -1.877 -1.76E-05 -1.865 -2.723 6.46E-03 0.109 1 ubiquinol-cytochrome c reductase core protein ii 53.104 928 "1,141" "1,285" 53.104 53.104 28.285 928 "1,388" "1,522" 28.285 28.285 ruditapes_c14 175.267 175.267 -175.267 -1.873 -1.24E-04 -1.86 -7.224 5.06E-13 5.01E-11 1.65E-08 ribosomal protein l15 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0005829 // cytosol /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 376.097 792 "1,278" "7,767" 376.097 376.097 200.83 792 582 "9,223" 200.83 200.83 ruditapes2_c603 20.008 20.008 -20.008 -1.872 -1.42E-05 -1.859 -2.439 0.015 0.208 1 cathepsin b /// 0005739 // mitochondrion /// 0006508 // proteolysis /// 0005515 // protein binding /// 0005764 // lysosome /// 0042470 // melanosome /// 0050790 // regulation of catalytic activity /// 0004197 // cysteine-type endopeptidase activity 42.966 939 269 "1,052" 42.966 42.966 22.958 939 344 "1,250" 22.958 22.958 ruditapes2_c3605 22.318 22.318 -22.318 -1.871 -1.58E-05 -1.858 -2.575 0.01 0.155 1 selenophosphate synthetase isoform 1 47.949 907 401 "1,134" 47.949 47.949 25.631 907 579 "1,348" 25.631 25.631 ruditapes_lrc36530 14.019 14.019 -14.019 -1.866 -9.95E-06 -1.853 -2.037 0.042 0.453 1 histone /// 0005811 // lipid particle /// 0005634 // nucleus /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0005700 // polytene chromosome /// 0000786 // nucleosome 30.212 721 4 568 30.212 30.212 16.193 721 7 677 16.193 16.193 ruditapes_c19690 15.066 15.066 -15.066 -1.863 -1.07E-05 -1.85 -2.109 0.035 0.402 1 voltage-dependent anion channel 1 /// 0007612 // learning /// 0046930 // pore complex /// 0005515 // protein binding /// 0007270 // nerve-nerve synaptic transmission /// 0001662 // behavioral fear response /// 0042645 // mitochondrial nucleoid /// 0005743 // mitochondrial inner membrane /// 0006820 // anion transport /// 0006851 // mitochondrial calcium ion transport /// 0005741 // mitochondrial outer membrane /// 0008308 // voltage-gated anion channel activity 32.532 468 397 397 32.532 32.532 17.467 468 474 474 17.467 17.467 ruditapes_lrc38716 28.293 28.293 -28.293 -1.854 -2.01E-05 -1.841 -2.879 3.99E-03 0.073 1 60s ribosomal protein l7a /// 0030529 // ribonucleoprotein complex 61.433 319 36 511 61.433 61.433 33.14 319 92 613 33.14 33.14 ruditapes_lrc34365 15.496 15.496 -15.496 -1.851 -1.10E-05 -1.838 -2.128 0.033 0.388 1 actin /// 0005524 // ATP binding /// 0005856 // cytoskeleton /// 0005515 // protein binding /// 0005737 // cytoplasm 33.714 976 318 858 33.714 33.714 18.218 976 377 "1,031" 18.218 18.218 ruditapes2_c3108 335.075 335.075 -335.075 -1.846 -2.38E-04 -1.833 -9.877 5.23E-23 1.05E-20 1.70E-18 ribosomal protein x-linked /// 0006414 // translational elongation /// 0008284 // positive regulation of cell proliferation /// 0045727 // positive regulation of translation /// 0019843 // rRNA binding /// 0005844 // polysome /// 0007420 // brain development /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0009790 // embryonic development 731.28 849 "2,522" "16,189" 731.28 731.28 396.205 849 "3,385" "19,505" 396.205 396.205 ruditapes2_c759 13.568 13.568 -13.568 -1.846 -9.63E-06 -1.833 -1.987 0.047 0.491 1 tubulin polymerization-promoting protein family member 3 29.607 "1,158" 102 894 29.607 29.607 16.039 "1,158" 115 "1,077" 16.039 16.039 ruditapes_c8290 11.955 11.955 -11.955 -1.836 -8.48E-06 -1.824 -1.858 0.063 0.603 1 dopamine beta hydroxylase 26.249 637 436 436 26.249 26.249 14.295 637 528 528 14.295 14.295 ruditapes2_c2593 12.321 12.321 -12.321 -1.836 -8.74E-06 -1.824 -1.886 0.059 0.58 1 histone h2a /// 0005634 // nucleus /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0000786 // nucleosome 27.06 805 114 568 27.06 27.06 14.739 805 149 688 14.739 14.739 ruditapes2_c6554 35.994 35.994 -35.994 -1.835 -2.55E-05 -1.823 -3.222 1.27E-03 0.028 1 solute carrier family 25 member 3 isoform b precursor isoform 6 /// 0006810 // transport /// 0006091 // generation of precursor metabolites and energy /// 0015320 // phosphate carrier activity /// 0005743 // mitochondrial inner membrane /// 0005887 // integral to plasma membrane 79.094 625 222 "1,289" 79.094 79.094 43.101 625 271 "1,562" 43.101 43.101 ruditapes2_c4732 349.827 349.827 -349.827 -1.821 -2.48E-04 -1.809 -9.985 1.78E-23 3.72E-21 5.80E-19 nadh dehydrogenase subunit 4l 775.937 507 "3,603" "10,258" 775.937 775.937 426.109 507 "2,679" "12,527" 426.109 426.109 ruditapes_lrc7057 16.428 16.428 -16.428 -1.819 -1.17E-05 -1.807 -2.161 0.031 0.365 1 calponin-like protein 36.483 "1,068" "1,016" "1,016" 36.483 36.483 20.055 "1,068" "1,242" "1,242" 20.055 20.055 ruditapes2_c773 296.305 296.305 -296.305 -1.819 -2.10E-04 -1.807 -9.18 4.31E-20 7.39E-18 1.41E-15 ribosomal protein s21 /// 0006414 // translational elongation /// 0047485 // protein N-terminus binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0043022 // ribosome binding 658.166 346 "1,548" "5,938" 658.166 658.166 361.862 346 "1,527" "7,260" 361.862 361.862 ruditapes_lrc33670 28.349 28.349 -28.349 -1.816 -2.01E-05 -1.803 -2.835 4.58E-03 0.082 1 ribosomal protein l10a /// 0006414 // translational elongation /// 0006396 // RNA processing /// 0005840 // ribosome /// 0005829 // cytosol /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0009653 // anatomical structure morphogenesis 63.101 595 63 979 63.101 63.101 34.752 595 54 "1,199" 34.752 34.752 ruditapes_lrc32562 10.259 10.259 -10.259 -1.813 -7.28E-06 -1.801 -1.704 0.088 0.751 1 elongation factor 1 delta /// 0006414 // translational elongation /// 0005515 // protein binding /// 0004871 // signal transducer activity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade /// 0005829 // cytosol 22.872 778 46 464 22.872 22.872 12.613 778 42 569 12.613 12.613 ruditapes2_c1668 9.574 9.574 -9.574 -1.809 -6.79E-06 -1.797 -1.642 0.1 0.808 1 mitochondrial ribosomal protein l52 21.411 609 323 340 21.411 21.411 11.837 609 385 418 11.837 11.837 ruditapes2_lrc4119 104.529 104.529 -104.529 -1.8 -7.41E-05 -1.788 -5.406 6.46E-08 3.60E-06 2.11E-03 dynein light chain 2 "/// 0005868 // cytoplasmic dynein complex /// 0002119 // nematode larval development /// 0007290 // spermatid nucleus elongation /// 0035046 // pronuclear migration /// 0040010 // positive regulation of growth rate /// 0042623 // ATPase activity, coupled /// 0007476 // imaginal disc-derived wing morphogenesis /// 0016459 // myosin complex /// 0051017 // actin filament bundle formation /// 0005634 // nucleus /// 0043186 // P granule /// 0008407 // bristle morphogenesis /// 0005886 // plasma membrane /// 0008039 // synaptic target recognition /// 0007291 // sperm individualization /// 0040011 // locomotion /// 0005829 // cytosol /// 0002009 // morphogenesis of an epithelium /// 0010171 // body morphogenesis /// 0005874 // microtubule /// 0040035 // hermaphrodite genitalia development /// 0008092 // cytoskeletal protein binding /// 0003777 // microtubule motor activity /// 0045505 // dynein intermediate chain binding /// 0042803 // protein homodimerization activity /// 0009792 // embryonic development ending in birth or egg hatching /// 0007018 // microtubule-based movement" 235.2 617 556 "3,784" 235.2 235.2 130.671 617 534 "4,675" 130.671 130.671 ruditapes2_c4998 375.416 375.416 -375.416 -1.796 -2.66E-04 -1.784 -10.226 1.52E-24 3.39E-22 4.95E-20 ribosomal protein l34a /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 847.248 423 "2,148" "9,345" 847.248 847.248 471.832 423 "2,980" "11,573" 471.832 471.832 ruditapes2_lrc5345 25.866 25.866 -25.866 -1.795 -1.83E-05 -1.783 -2.683 7.29E-03 0.121 1 40s ribosomal protein s10 /// 0005840 // ribosome 58.383 716 278 "1,090" 58.383 58.383 32.516 716 271 "1,350" 32.516 32.516 ruditapes_c27686 10.499 10.499 -10.499 -1.794 -7.45E-06 -1.782 -1.708 0.088 0.746 1 tgf beta-inducible nuclear protein 1 23.725 472 258 292 23.725 23.725 13.227 472 337 362 13.227 13.227 ruditapes2_c4169 62.177 62.177 -62.177 -1.791 -4.41E-05 -1.779 -4.153 3.29E-05 1.12E-03 1 ribosomal protein l9 /// 0030529 // ribonucleoprotein complex 140.736 760 12 "2,789" 140.736 140.736 78.559 760 4 "3,462" 78.559 78.559 ruditapes2_lrc4479 10.826 10.826 -10.826 -1.791 -7.68E-06 -1.779 -1.732 0.083 0.723 1 ribosomal protein s19 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 24.517 718 16 459 24.517 24.517 13.691 718 12 570 13.691 13.691 ruditapes2_lrc4623 13.402 13.402 -13.402 -1.788 -9.50E-06 -1.776 -1.925 0.054 0.545 1 nucleoside diphosphate kinase /// 0005524 // ATP binding /// 0007424 // open tracheal system development /// 0006468 // protein amino acid phosphorylation /// 0006183 // GTP biosynthetic process /// 0006241 // CTP biosynthetic process /// 0004550 // nucleoside diphosphate kinase activity /// 0006228 // UTP biosynthetic process 30.402 772 140 612 30.402 30.402 17 772 226 761 17 17 ruditapes_c11289 11.679 11.679 -11.679 -1.786 -8.28E-06 -1.773 -1.795 0.073 0.663 1 solute carrier family 6 (neurotransmitter transporter) member 14 /// 0022804 // active transmembrane transporter activity /// 0043231 // intracellular membrane-bounded organelle /// 0022891 // substrate-specific transmembrane transporter activity /// 0044459 // plasma membrane part 26.548 "1,030" 713 713 26.548 26.548 14.868 "1,030" 888 888 14.868 14.868 ruditapes2_c681 216.235 216.235 -216.235 -1.784 -1.53E-04 -1.772 -7.718 1.18E-14 1.35E-12 3.84E-10 heterogeneous nuclear ribonucleoprotein d-like /// 0030529 // ribonucleoprotein complex /// 0005634 // nucleus /// 0005515 // protein binding /// 0010467 // gene expression /// 0003723 // RNA binding /// 0016070 // RNA metabolic process /// 0043566 // structure-specific DNA binding 492.012 "1,002" "3,339" "12,855" 492.012 492.012 275.777 "1,002" "5,064" "16,023" 275.777 275.777 ruditapes_c4628 153.474 153.474 -153.474 -1.783 -1.09E-04 -1.771 -6.5 8.05E-11 6.54E-09 2.62E-06 alpha 3d "/// 0005524 // ATP binding /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0016021 // integral to membrane /// 0005874 // microtubule /// 0042626 // ATPase activity, coupled to transmembrane movement of substances /// 0007018 // microtubule-based movement" 349.409 595 "2,884" "5,421" 349.409 349.409 195.935 595 "3,062" "6,760" 195.935 195.935 ruditapes_lrc33892 293.431 293.431 -293.431 -1.772 -2.08E-04 -1.76 -8.942 3.84E-19 5.96E-17 1.25E-14 ribosomal protein l11 /// 0006414 // translational elongation /// 0002119 // nematode larval development /// 0006605 // protein targeting /// 0040010 // positive regulation of growth rate /// 0005730 // nucleolus /// 0000003 // reproduction /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development /// 0042273 // ribosomal large subunit biogenesis 673.35 606 451 "10,640" 673.35 673.35 379.919 606 650 "13,350" 379.919 379.919 ruditapes_lrc13862 11.321 11.321 -11.321 -1.772 -8.03E-06 -1.76 -1.756 0.079 0.697 1 ribosomal protein l21 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 25.979 620 0 420 25.979 25.979 14.659 620 0 527 14.659 14.659 ruditapes_lrc32401 11.61 11.61 -11.61 -1.767 -8.23E-06 -1.755 -1.774 0.076 0.683 1 atp synthase d chain /// 0005811 // lipid particle 26.749 876 199 611 26.749 26.749 15.139 876 287 769 15.139 15.139 ruditapes2_lrc3246 275.823 275.823 -275.823 -1.761 -1.96E-04 -1.749 -8.621 6.61E-18 9.67E-16 2.16E-13 alpha-tubulin /// 0007638 // mechanosensory behavior /// 0005874 // microtubule /// 0007017 // microtubule-based process 638.292 839 "6,939" "13,964" 638.292 638.292 362.469 839 "6,779" "17,634" 362.469 362.469 ruditapes_lrc17737 120.399 120.399 -120.399 -1.761 -8.54E-05 -1.749 -5.695 1.24E-08 7.84E-07 4.03E-04 ribosomal protein l39 /// 0022625 // cytosolic large ribosomal subunit /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0003735 // structural constituent of ribosome 278.675 439 "1,196" "3,190" 278.675 278.675 158.276 439 "1,236" "4,029" 158.276 158.276 ruditapes2_c3278 269.985 269.985 -269.985 -1.755 -1.91E-04 -1.743 -8.506 1.80E-17 2.56E-15 5.87E-13 ribosomal protein s21 /// 0006414 // translational elongation /// 0047485 // protein N-terminus binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0043022 // ribosome binding 627.433 344 "1,550" "5,628" 627.433 627.433 357.448 344 "1,576" "7,130" 357.448 357.448 ruditapes_c1848 10.58 10.58 -10.58 -1.751 -7.50E-06 -1.739 -1.68 0.093 0.774 1 gustatory receptor candidate 19 24.674 558 180 359 24.674 24.674 14.093 558 253 456 14.093 14.093 ruditapes2_c1414 13.671 13.671 -13.671 -1.746 -9.69E-06 -1.734 -1.905 0.057 0.563 1 glioma tumor suppressor candidate region gene 2 32.002 "1,335" 736 "1,114" 32.002 32.002 18.331 "1,335" 862 "1,419" 18.331 18.331 ruditapes_c36527 72.472 72.472 -72.472 -1.745 -5.14E-05 -1.733 -4.383 1.17E-05 4.44E-04 0.381 ribosomal protein l24 /// 0010458 // exit from mitosis /// 0006414 // translational elongation /// 0021554 // optic nerve development /// 0005515 // protein binding /// 0031575 // G1/S transition checkpoint /// 0022625 // cytosolic large ribosomal subunit /// 0031290 // retinal ganglion cell axon guidance /// 0000027 // ribosomal large subunit assembly /// 0060041 // retina development in camera-type eye /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 169.785 515 172 "2,280" 169.785 169.785 97.313 515 180 "2,906" 97.313 97.313 ruditapes2_c3098 14.772 14.772 -14.772 -1.743 -1.05E-05 -1.731 -1.977 0.048 0.5 1 protein /// 0044237 // cellular metabolic process 34.666 "1,426" 608 "1,289" 34.666 34.666 19.894 "1,426" 606 "1,645" 19.894 19.894 ruditapes_c10674 12.97 12.97 -12.97 -1.74 -9.19E-06 -1.728 -1.85 0.064 0.61 1 novel protein (zgc:153646) 30.494 371 295 295 30.494 30.494 17.525 371 377 377 17.525 17.525 ruditapes2_c2174 162.048 162.048 -162.048 -1.74 -1.15E-04 -1.728 -6.54 6.17E-11 5.09E-09 2.01E-06 poly a binding cytoplasmic 1 b /// 0031370 // eukaryotic initiation factor 4G binding /// 0008266 // poly(U) RNA binding /// 0007596 // blood coagulation /// 0000166 // nucleotide binding /// 0060212 // negative regulation of nuclear-transcribed mRNA poly(A) tail shortening /// 0005844 // polysome /// 0043621 // protein self-association /// 0005737 // cytoplasm /// 0008270 // zinc ion binding /// 0008143 // poly(A) RNA binding /// 0048255 // mRNA stabilization /// 0017130 // poly(C) RNA binding /// 0006417 // regulation of translation 380.989 "1,067" "10,600" "10,600" 380.989 380.989 218.942 "1,067" "13,546" "13,546" 218.942 218.942 ruditapes2_c4994 105.755 105.755 -105.755 -1.736 -7.50E-05 -1.724 -5.271 1.36E-07 7.14E-06 4.43E-03 ribosomal protein l26 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0042273 // ribosomal large subunit biogenesis 249.521 553 363 "3,598" 249.521 249.521 143.767 553 466 "4,610" 143.767 143.767 ruditapes2_lrc2890 10.561 10.561 -10.561 -1.734 -7.48E-06 -1.722 -1.664 0.096 0.788 1 ribosomal protein s7 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 24.955 647 0 421 24.955 24.955 14.394 647 1 540 14.394 14.394 ruditapes2_c3119 97.859 97.859 -97.859 -1.733 -6.94E-05 -1.721 -5.063 4.13E-07 2.02E-05 0.013 myosin alkali light chain 1 /// 0005509 // calcium ion binding 231.405 "1,237" "1,129" "7,464" 231.405 231.405 133.547 "1,237" "1,871" "9,579" 133.547 133.547 ruditapes_c936 10.479 10.479 -10.479 -1.731 -7.43E-06 -1.719 -1.655 0.098 0.796 1 tpa_inf: variable region-containing chitin-binding protein 2 24.822 618 137 400 24.822 24.822 14.344 618 122 514 14.344 14.344 ruditapes2_lrc4983 11.866 11.866 -11.866 -1.73 -8.41E-06 -1.718 -1.76 0.078 0.693 1 ribosomal protein l35a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome /// 0000049 // tRNA binding /// 0042273 // ribosomal large subunit biogenesis 28.13 439 1 322 28.13 28.13 16.264 439 4 414 16.264 16.264 ruditapes_lrc13423 18.199 18.199 -18.199 -1.73 -1.29E-05 -1.719 -2.18 0.029 0.353 1 ribosomal protein s3 /// 0006414 // translational elongation /// 0019901 // protein kinase binding /// 0006919 // activation of caspase activity /// 0032088 // negative regulation of NF-kappaB transcription factor activity /// 0005634 // nucleus /// 0004519 // endonuclease activity /// 0006413 // translational initiation /// 0045738 // negative regulation of DNA repair /// 0003729 // mRNA binding /// 0012505 // endomembrane system /// 0006917 // induction of apoptosis /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0032587 // ruffle membrane /// 0051059 // NF-kappaB binding /// 0003684 // damaged DNA binding /// 0030425 // dendrite /// 0003906 // DNA-(apurinic or apyrimidinic site) lyase activity /// 0009790 // embryonic development /// 0051536 // iron-sulfur cluster binding 43.121 820 57 922 43.121 43.121 24.922 820 34 "1,185" 24.922 24.922 ruditapes2_c46 821.02 821.02 -821.02 -1.725 -5.82E-04 -1.714 -14.617 2.21E-48 9.35E-46 7.20E-44 elongation factor 2 /// 0006414 // translational elongation /// 0042221 // response to chemical stimulus /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0005515 // protein binding /// 0005737 // cytoplasm /// 0003746 // translation elongation factor activity "1,952.73" 961 "16,909" "48,932" "1,952.73" "1,952.73" "1,131.71" 961 "21,044" "63,063" "1,131.71" "1,131.71" ruditapes2_lrc3852 37.661 37.661 -37.661 -1.719 -2.67E-05 -1.707 -3.118 1.82E-03 0.038 1 guanine nucleotide binding protein (g protein) beta polypeptide 2-like 1 /// 0005080 // protein kinase C binding /// 0007205 // activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway /// 0019903 // protein phosphatase binding /// 0005886 // plasma membrane /// 0043025 // cell soma /// 0005737 // cytoplasm /// 0005102 // receptor binding 90.038 808 232 "1,897" 90.038 90.038 52.378 808 230 "2,454" 52.378 52.378 ruditapes_lrc19580 33.9 33.9 -33.9 -1.717 -2.40E-05 -1.705 -2.955 3.13E-03 0.059 1 vdg3 [Mytilus edulis] 81.197 435 860 921 81.197 81.197 47.297 435 "1,080" "1,193" 47.297 47.297 ruditapes_lrc11074 525.444 525.444 -525.444 -1.714 -3.72E-04 -1.702 -11.62 3.26E-31 9.66E-29 1.06E-26 ribosomal protein l36 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0003735 // structural constituent of ribosome "1,261.43" 436 "7,880" "14,341" "1,261.43" "1,261.43" 735.99 436 "8,201" "18,607" 735.99 735.99 ruditapes_lrc26499 41.952 41.952 -41.952 -1.711 -2.97E-05 -1.699 -3.277 1.05E-03 0.024 1 60s acidic ribosomal protein p2 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0003735 // structural constituent of ribosome 100.981 447 90 "1,177" 100.981 100.981 59.029 447 32 "1,530" 59.029 59.029 ruditapes2_c3647 35.526 35.526 -35.526 -1.71 -2.52E-05 -1.698 -3.014 2.58E-03 0.051 1 ribosomal protein l13 /// 0006414 // translational elongation /// 0051726 // regulation of cell cycle /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit 85.568 692 21 "1,544" 85.568 85.568 50.043 692 22 "2,008" 50.043 50.043 ruditapes2_lrc5253 119.892 119.892 -119.892 -1.705 -8.49E-05 -1.693 -5.523 3.34E-08 1.95E-06 1.09E-03 ribosomal protein l13 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit 289.957 692 74 "5,232" 289.957 289.957 170.065 692 78 "6,824" 170.065 170.065 ruditapes_c34139 19.808 19.808 -19.808 -1.703 -1.40E-05 -1.691 -2.242 0.025 0.311 1 ribosomal protein l24 /// 0010458 // exit from mitosis /// 0006414 // translational elongation /// 0021554 // optic nerve development /// 0005515 // protein binding /// 0031575 // G1/S transition checkpoint /// 0022625 // cytosolic large ribosomal subunit /// 0031290 // retinal ganglion cell axon guidance /// 0000027 // ribosomal large subunit assembly /// 0060041 // retina development in camera-type eye /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development 47.993 525 1 657 47.993 47.993 28.184 525 8 858 28.184 28.184 ruditapes2_c3369 26.792 26.792 -26.792 -1.699 -1.90E-05 -1.688 -2.602 9.26E-03 0.146 1 arginine kinase /// 0016740 // transferase activity 65.103 "1,359" "1,353" "2,307" 65.103 65.103 38.311 "1,359" "1,340" "3,019" 38.311 38.311 ruditapes_lrc32644 44.658 44.658 -44.658 -1.697 -3.16E-05 -1.685 -3.355 7.93E-04 0.019 1 receptor of activated kinase c 1 /// 0019903 // protein phosphatase binding /// 0005886 // plasma membrane /// 0043025 // cell soma /// 0005737 // cytoplasm /// 0005102 // receptor binding 108.753 688 136 "1,951" 108.753 108.753 64.095 688 117 "2,557" 64.095 64.095 ruditapes2_c927 20.615 20.615 -20.615 -1.696 -1.46E-05 -1.685 -2.279 0.023 0.288 1 cathepsin l precursor /// 0006508 // proteolysis /// 0004197 // cysteine-type endopeptidase activity 50.217 850 967 "1,113" 50.217 50.217 29.602 850 "1,221" "1,459" 29.602 29.602 ruditapes_c469 11.932 11.932 -11.932 -1.687 -8.45E-06 -1.675 -1.725 0.085 0.73 1 dolichyl-diphosphooligosaccharide-protein glycosyltransferase /// 0018279 // protein amino acid N-linked glycosylation via asparagine /// 0006496 // protein amino acid terminal N-glycosylation /// 0005515 // protein binding /// 0034097 // response to cytokine stimulus /// 0016021 // integral to membrane /// 0008250 // oligosaccharyltransferase complex /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity /// 0005792 // microsome /// 0042110 // T cell activation 29.306 "1,077" 659 823 29.306 29.306 17.374 "1,077" 883 "1,085" 17.374 17.374 ruditapes2_lrc2144 34.838 34.838 -34.838 -1.686 -2.47E-05 -1.675 -2.946 3.22E-03 0.061 1 histone h2a /// 0005694 // chromosome 85.606 534 114 "1,192" 85.606 85.606 50.768 534 123 "1,572" 50.768 50.768 ruditapes2_lrc4425 13.811 13.811 -13.811 -1.686 -9.78E-06 -1.675 -1.855 0.064 0.605 1 ribosomal protein l21 33.931 564 1 499 33.931 33.931 20.12 564 1 658 20.12 20.12 ruditapes_s39096 91.977 91.977 -91.977 -1.685 -6.51E-05 -1.673 -4.783 1.73E-06 7.77E-05 0.056 40s ribosomal protein s3 /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development 226.341 316 500 "1,865" 226.341 226.341 134.364 316 348 "2,462" 134.364 134.364 ruditapes2_lrc3404 20.844 20.844 -20.844 -1.678 -1.48E-05 -1.666 -2.268 0.023 0.295 1 cytoplasmic actin /// 0005524 // ATP binding /// 0005856 // cytoskeleton /// 0005515 // protein binding /// 0005737 // cytoplasm 51.601 411 138 553 51.601 51.601 30.757 411 225 733 30.757 30.757 ruditapes2_c3334 78.851 78.851 -78.851 -1.677 -5.58E-05 -1.666 -4.41 1.04E-05 3.97E-04 0.338 ribosomal protein l5 /// 0006414 // translational elongation /// 0005634 // nucleus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0008097 // 5S rRNA binding /// 0042273 // ribosomal large subunit biogenesis 195.335 985 233 "5,017" 195.335 195.335 116.483 985 305 "6,653" 116.483 116.483 ruditapes_lrc35398 38.737 38.737 -38.737 -1.672 -2.74E-05 -1.66 -3.081 2.06E-03 0.042 1 slc25a3-prov protein /// 0006810 // transport /// 0005488 // binding /// 0015317 // phosphate:hydrogen symporter activity /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane 96.422 809 613 "2,034" 96.422 96.422 57.685 809 832 "2,706" 57.685 57.685 ruditapes_c408 165.298 165.298 -165.298 -1.669 -1.17E-04 -1.658 -6.358 2.05E-10 1.60E-08 6.68E-06 atp:adp antiporter /// 0005488 // binding /// 0015865 // purine nucleotide transport /// 0005471 // ATP:ADP antiporter activity /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane /// 0009536 // plastid 412.21 "1,308" 854 "14,059" 412.21 412.21 246.912 "1,308" "1,898" "18,727" 246.912 246.912 ruditapes2_lrc5556 17.406 17.406 -17.406 -1.668 -1.23E-05 -1.657 -2.061 0.039 0.436 1 40s ribosomal protein s14 /// 0030529 // ribonucleoprotein complex 43.469 487 14 552 43.469 43.469 26.063 487 15 736 26.063 26.063 ruditapes2_lrc4923 121.183 121.183 -121.183 -1.667 -8.58E-05 -1.656 -5.435 5.47E-08 3.07E-06 1.78E-03 ribosomal protein l11 /// 0006414 // translational elongation /// 0006605 // protein targeting /// 0005730 // nucleolus /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0042273 // ribosomal large subunit biogenesis 302.89 578 267 "4,565" 302.89 302.89 181.707 578 258 "6,090" 181.707 181.707 ruditapes_lrc34296 13.798 13.798 -13.798 -1.667 -9.77E-06 -1.656 -1.834 0.067 0.624 1 slc25a3-prov protein /// 0006810 // transport /// 0005488 // binding /// 0015317 // phosphate:hydrogen symporter activity /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane 34.479 743 232 668 34.479 34.479 20.681 743 270 891 20.681 20.681 ruditapes_lrc32594 20.205 20.205 -20.205 -1.662 -1.43E-05 -1.651 -2.213 0.027 0.33 1 apextrin 50.729 852 102 "1,127" 50.729 50.729 30.524 852 147 "1,508" 30.524 30.524 ruditapes_c242 53.873 53.873 -53.873 -1.66 -3.81E-05 -1.649 -3.61 3.07E-04 8.28E-03 1 small ubiquitin-related modifier 3 precursor /// 0019941 // modification-dependent protein catabolic process /// 0000776 // kinetochore /// 0005515 // protein binding /// 0005737 // cytoplasm /// 0006464 // protein modification process 135.479 "1,179" "1,689" "4,165" 135.479 135.479 81.606 "1,179" "2,787" "5,579" 81.606 81.606 ruditapes_lrc34372 101.241 101.241 -101.241 -1.656 -7.17E-05 -1.645 -4.936 7.98E-07 3.74E-05 0.026 ribosomal protein l7 /// 0015934 // large ribosomal subunit /// 0030528 // transcription regulator activity /// 0006412 // translation /// 0003735 // structural constituent of ribosome 255.622 789 241 "5,259" 255.622 255.622 154.381 789 351 "7,063" 154.381 154.381 ruditapes_lrc34197 232.992 232.992 -232.992 -1.651 -1.65E-04 -1.64 -7.469 8.06E-14 8.42E-12 2.63E-09 large subunit ribosomal protein 30 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 590.625 579 137 "8,917" 590.625 590.625 357.633 579 218 "12,007" 357.633 357.633 ruditapes2_c5219 24.992 24.992 -24.992 -1.65 -1.77E-05 -1.639 -2.444 0.015 0.206 1 large subunit ribosomal protein 30 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 63.444 405 5 670 63.444 63.444 38.452 405 7 903 38.452 38.452 ruditapes_c2959 26.971 26.971 -26.971 -1.649 -1.91E-05 -1.637 -2.537 0.011 0.169 1 glutathione peroxidase 3 /// 0005615 // extracellular space /// 0042744 // hydrogen peroxide catabolic process /// 0008430 // selenium binding /// 0008134 // transcription factor binding /// 0006982 // response to lipid hydroperoxide /// 0004602 // glutathione peroxidase activity /// 0051289 // protein homotetramerization 68.557 970 474 "1,734" 68.557 68.557 41.585 970 625 "2,339" 41.585 41.585 ruditapes2_lrc4098 426.826 426.826 -426.826 -1.648 -3.02E-04 -1.637 -10.089 6.21E-24 1.33E-21 2.03E-19 ribosomal protein s27a /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0006414 // translational elongation /// 0046872 // metal ion binding /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005515 // protein binding /// 0005654 // nucleoplasm /// 0030433 // ER-associated protein catabolic process /// 0030528 // transcription regulator activity /// 0016567 // protein ubiquitination /// 0003735 // structural constituent of ribosome /// 0048167 // regulation of synaptic plasticity /// 0022627 // cytosolic small ribosomal subunit /// 0007411 // axon guidance /// 0045941 // positive regulation of transcription /// 0042062 // long-term strengthening of neuromuscular junction "1,085.79" 519 "2,760" "14,694" "1,085.79" "1,085.79" 658.96 519 "2,367" "19,831" 658.96 658.96 ruditapes_lrc34463 22.198 22.198 -22.198 -1.647 -1.57E-05 -1.636 -2.299 0.022 0.277 1 ribosomal protein l35a /// 0002119 // nematode larval development /// 0040010 // positive regulation of growth rate /// 0000003 // reproduction /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0040017 // positive regulation of locomotion /// 0009792 // embryonic development ending in birth or egg hatching 56.526 422 109 622 56.526 56.526 34.328 422 67 840 34.328 34.328 ruditapes2_c587 "1,671.88" "1,671.88" "-1,671.88" -1.645 -1.18E-03 -1.634 -19.951 1.51E-88 1.09E-85 4.91E-84 nadh dehydrogenase subunit 2 /// 0005739 // mitochondrion /// 0042773 // ATP synthesis coupled electron transport /// 0016491 // oxidoreductase activity "4,264.86" "1,293" "127,778" "143,791" "4,264.86" "4,264.86" "2,592.99" "1,293" "183,530" "194,409" "2,592.99" "2,592.99" ruditapes2_c635 22.602 22.602 -22.602 -1.645 -1.60E-05 -1.634 -2.317 0.021 0.268 1 profilin /// 0015629 // actin cytoskeleton /// 0003779 // actin binding /// 0005737 // cytoplasm /// 0030036 // actin cytoskeleton organization 57.655 "1,627" 788 "2,446" 57.655 57.655 35.053 "1,627" "1,385" "3,307" 35.053 35.053 ruditapes_lrc33919 13.361 13.361 -13.361 -1.643 -9.46E-06 -1.632 -1.779 0.075 0.678 1 40s ribosomal protein s20 /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome 34.154 530 64 472 34.154 34.154 20.793 530 69 639 20.793 20.793 ruditapes_lrc38273 116.552 116.552 -116.552 -1.642 -8.25E-05 -1.631 -5.253 1.50E-07 7.84E-06 4.88E-03 ribosomal protein l32 298.055 469 473 "3,645" 298.055 298.055 181.503 469 615 "4,936" 181.503 181.503 ruditapes_lrc25552 16.02 16.02 -16.02 -1.64 -1.13E-05 -1.629 -1.945 0.052 0.527 1 cytochrome somatic /// 0042981 // regulation of apoptosis /// 0022900 // electron transport chain /// 0044429 // mitochondrial part /// 0009055 // electron carrier activity /// 0005506 // iron ion binding 41.054 837 166 896 41.054 41.054 25.034 837 222 "1,215" 25.034 25.034 ruditapes2_lrc3339 19.759 19.759 -19.759 -1.631 -1.40E-05 -1.62 -2.147 0.032 0.374 1 ribosomal protein l11 /// 0006414 // translational elongation /// 0006605 // protein targeting /// 0005730 // nucleolus /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development /// 0042273 // ribosomal large subunit biogenesis 51.09 584 35 778 51.09 51.09 31.332 584 36 "1,061" 31.332 31.332 ruditapes2_c683 25.007 25.007 -25.007 -1.63 -1.77E-05 -1.619 -2.415 0.016 0.218 1 calmodulin /// 0005524 // ATP binding /// 0042981 // regulation of apoptosis /// 0005516 // calmodulin binding /// 0005513 // detection of calcium ion /// 0043277 // apoptotic cell clearance /// 0030424 // axon /// 0019904 // protein domain specific binding /// 0031997 // N-terminal myristoylation domain binding /// 0051383 // kinetochore organization /// 0007268 // synaptic transmission /// 0040010 // positive regulation of growth rate /// 0008049 // male courtship behavior /// 0032036 // myosin heavy chain binding /// 0005634 // nucleus /// 0051533 // positive regulation of NFAT protein import into nucleus /// 0051726 // regulation of cell cycle /// 0006468 // protein amino acid phosphorylation /// 0048786 // presynaptic active zone /// 0005886 // plasma membrane /// 0045211 // postsynaptic membrane /// 0005876 // spindle microtubule /// 0031432 // titin binding /// 0051489 // regulation of filopodium assembly /// 0000922 // spindle pole /// 0016060 // metarhodopsin inactivation /// 0005829 // cytosol /// 0004721 // phosphoprotein phosphatase activity /// 0005813 // centrosome /// 0016062 // adaptation of rhodopsin mediated signaling /// 0008270 // zinc ion binding /// 0007528 // neuromuscular junction development /// 0005954 // calcium- and calmodulin-dependent protein kinase complex /// 0007616 // long-term memory /// 0005506 // iron ion binding /// 0004683 // calmodulin-dependent protein kinase activity /// 0005509 // calcium ion binding /// 0032465 // regulation of cytokinesis /// 0016061 // regulation of light-activated channel activity /// 0043388 // positive regulation of DNA binding /// 0016028 // rhabdomere /// 0016477 // cell migration /// 0030425 // dendrite /// 0009792 // embryonic development ending in birth or egg hatching /// 0007052 // mitotic spindle organization 64.693 923 "1,021" "1,557" 64.693 64.693 39.686 923 "1,387" "2,124" 39.686 39.686 ruditapes2_c138 21.304 21.304 -21.304 -1.627 -1.51E-05 -1.616 -2.225 0.026 0.322 1 protein 55.264 "1,331" 404 "1,918" 55.264 55.264 33.96 "1,331" 531 "2,621" 33.96 33.96 ruditapes_c2889 48.162 48.162 -48.162 -1.627 -3.41E-05 -1.616 -3.345 8.22E-04 0.019 1 ribosomal protein l7 /// 0015934 // large ribosomal subunit /// 0030528 // transcription regulator activity /// 0006412 // translation /// 0003735 // structural constituent of ribosome 124.957 755 167 "2,460" 124.957 124.957 76.795 755 211 "3,362" 76.795 76.795 ruditapes2_c3112 35.33 35.33 -35.33 -1.622 -2.50E-05 -1.611 -2.857 4.28E-03 0.077 1 mitochondrial atp synthase alpha subunit "/// 0005524 // ATP binding /// 0005759 // mitochondrial matrix /// 0043499 // eukaryotic cell surface binding /// 0005811 // lipid particle /// 0002119 // nematode larval development /// 0040010 // positive regulation of growth rate /// 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0005886 // plasma membrane /// 0015986 // ATP synthesis coupled proton transport /// 0006629 // lipid metabolic process /// 0046961 // proton-transporting ATPase activity, rotational mechanism /// 0006911 // phagocytosis, engulfment /// 0008340 // determination of adult lifespan /// 0007286 // spermatid development /// 0001937 // negative regulation of endothelial cell proliferation /// 0042288 // MHC class I protein binding /// 0009792 // embryonic development ending in birth or egg hatching /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism" 92.102 757 504 "1,818" 92.102 92.102 56.772 757 790 "2,492" 56.772 56.772 ruditapes_c2074 60.771 60.771 -60.771 -1.614 -4.30E-05 -1.603 -3.728 1.93E-04 5.56E-03 1 40s ribosomal protein s9 /// 0006414 // translational elongation /// 0008284 // positive regulation of cell proliferation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0019843 // rRNA binding /// 0045182 // translation regulator activity /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 159.695 451 739 "1,878" 159.695 159.695 98.924 451 "1,104" "2,587" 98.924 98.924 ruditapes2_lrc4221 44.965 44.965 -44.965 -1.612 -3.18E-05 -1.601 -3.202 1.37E-03 0.03 1 ubiquitin a-52 residue ribosomal protein fusion product 1 "/// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process /// 0006355 // regulation of transcription, DNA-dependent /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005811 // lipid particle /// 0006950 // response to stress /// 0006414 // translational elongation /// 0042254 // ribosome biogenesis /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005515 // protein binding /// 0005654 // nucleoplasm /// 0022625 // cytosolic large ribosomal subunit /// 0030433 // ER-associated protein catabolic process /// 0030528 // transcription regulator activity /// 0016567 // protein ubiquitination /// 0006325 // chromatin organization /// 0003735 // structural constituent of ribosome /// 0048167 // regulation of synaptic plasticity /// 0007411 // axon guidance /// 0045941 // positive regulation of transcription /// 0042062 // long-term strengthening of neuromuscular junction" 118.436 442 139 "1,365" 118.436 118.436 73.47 442 125 "1,883" 73.47 73.47 ruditapes2_c5587 99.08 99.08 -99.08 -1.609 -7.01E-05 -1.598 -4.743 2.10E-06 9.26E-05 0.069 60s ribosomal protein l23a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0000166 // nucleotide binding /// 0003735 // structural constituent of ribosome 261.772 551 426 "3,761" 261.772 261.772 162.692 551 474 "5,198" 162.692 162.692 ruditapes2_c185 32.807 32.807 -32.807 -1.6 -2.32E-05 -1.589 -2.713 6.66E-03 0.112 1 arginine kinase 87.487 "1,248" "1,668" "2,847" 87.487 87.487 54.681 "1,248" "2,079" "3,957" 54.681 54.681 ruditapes2_lrc5603 114.745 114.745 -114.745 -1.6 -8.12E-05 -1.589 -5.073 3.91E-07 1.92E-05 0.013 ribosomal protein l32 /// 0006414 // translational elongation /// 0005515 // protein binding /// 0022625 // cytosolic large ribosomal subunit 306.12 392 221 "3,129" 306.12 306.12 191.375 392 382 "4,350" 191.375 191.375 ruditapes2_c142 263.261 263.261 -263.261 -1.597 -1.86E-04 -1.586 -7.673 1.69E-14 1.89E-12 5.49E-10 40s ribosomal protein s23 /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0003735 // structural constituent of ribosome 704.185 492 "5,436" "9,034" 704.185 704.185 440.923 492 "9,902" "12,579" 440.923 440.923 ruditapes2_c1043 149.523 149.523 -149.523 -1.595 -1.06E-04 -1.584 -5.773 7.79E-09 5.11E-07 2.54E-04 ribosomal protein s6 /// 0048471 // perinuclear region of cytoplasm /// 0043066 // negative regulation of apoptosis /// 0006414 // translational elongation /// 0001890 // placenta development /// 0005730 // nucleolus /// 0043065 // positive regulation of apoptosis /// 0005515 // protein binding /// 0042274 // ribosomal small subunit biogenesis /// 0031575 // G1/S transition checkpoint /// 0031929 // TOR signaling pathway /// 0006924 // activation-induced cell death of T cells /// 0005844 // polysome /// 0006364 // rRNA processing /// 0000082 // G1/S transition of mitotic cell cycle /// 0002309 // T cell proliferation during immune response /// 0042593 // glucose homeostasis /// 0022605 // oogenesis stage /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0033077 // T cell differentiation in the thymus /// 0007067 // mitosis /// 0007369 // gastrulation /// 0048821 // erythrocyte development 400.912 813 491 "8,499" 400.912 400.912 251.389 813 "1,210" "11,851" 251.389 251.389 ruditapes2_lrc4878 97.525 97.525 -97.525 -1.592 -6.90E-05 -1.582 -4.654 3.25E-06 1.39E-04 0.106 40s ribosomal protein s14 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 262.178 495 121 "3,384" 262.178 262.178 164.653 495 134 "4,726" 164.653 164.653 ruditapes_lrc32229 13.567 13.567 -13.567 -1.591 -9.59E-06 -1.58 -1.734 0.083 0.72 1 nascent polypeptide-associated complex subunit alpha /// 0003713 // transcription coactivator activity /// 0006350 // transcription /// 0005634 // nucleus /// 0006412 // translation /// 0005854 // nascent polypeptide-associated complex /// 0016787 // hydrolase activity /// 0017025 // TATA-binding protein binding 36.522 734 24 699 36.522 36.522 22.955 734 38 977 22.955 22.955 ruditapes_c38334 68.489 68.489 -68.489 -1.591 -4.84E-05 -1.58 -3.897 9.74E-05 3.00E-03 1 ribosomal protein l35 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005515 // protein binding /// 0003729 // mRNA binding /// 0022625 // cytosolic large ribosomal subunit /// 0003735 // structural constituent of ribosome 184.367 431 444 "2,072" 184.367 184.367 115.879 431 667 "2,896" 115.879 115.879 ruditapes2_c237 27.329 27.329 -27.329 -1.587 -1.93E-05 -1.576 -2.455 0.014 0.201 1 cofi_gibze ame: full=cofilin ame: full=actin-depolymerizing factor 1 /// 0044424 // intracellular part 73.893 "1,270" "1,121" "2,447" 73.893 73.893 46.564 "1,270" "1,345" "3,429" 46.564 46.564 ruditapes_lrc34753 139.469 139.469 -139.469 -1.583 -9.86E-05 -1.572 -5.531 3.19E-08 1.87E-06 1.04E-03 ribosomal protein s15 /// 0005840 // ribosome 378.73 530 842 "5,234" 378.73 378.73 239.26 530 732 "7,353" 239.26 239.26 ruditapes_lrc34295 26.978 26.978 -26.978 -1.578 -1.91E-05 -1.567 -2.424 0.015 0.214 1 ribosomal protein l18a /// 0006414 // translational elongation /// 0030529 // ribonucleoprotein complex /// 0005515 // protein binding /// 0005829 // cytosol 73.652 327 2 628 73.652 73.652 46.674 327 1 885 46.674 46.674 ruditapes_c34961 56.955 56.955 -56.955 -1.571 -4.03E-05 -1.56 -3.504 4.58E-04 0.012 1 ribosomal protein l24 /// 0010458 // exit from mitosis /// 0006414 // translational elongation /// 0021554 // optic nerve development /// 0005515 // protein binding /// 0031575 // G1/S transition checkpoint /// 0022625 // cytosolic large ribosomal subunit /// 0031290 // retinal ganglion cell axon guidance /// 0000027 // ribosomal large subunit assembly /// 0060041 // retina development in camera-type eye /// 0003723 // RNA binding /// 0003735 // structural constituent of ribosome /// 0009790 // embryonic development 156.744 482 257 "1,970" 156.744 156.744 99.789 482 240 "2,789" 99.789 99.789 ruditapes_c15263 103.242 103.242 -103.242 -1.569 -7.30E-05 -1.559 -4.714 2.44E-06 1.06E-04 0.079 elongation factor-2 284.604 672 "4,925" "4,987" 284.604 284.604 181.363 672 "6,876" "7,067" 181.363 181.363 ruditapes2_lrc3718 176.203 176.203 -176.203 -1.563 -1.25E-04 -1.553 -6.132 8.68E-10 6.49E-08 2.83E-05 ferritin /// 0006826 // iron ion transport /// 0016491 // oxidoreductase activity /// 0006879 // cellular iron ion homeostasis /// 0008199 // ferric iron binding 489.027 503 "2,541" "6,414" 489.027 489.027 312.824 503 "2,783" "9,124" 312.824 312.824 ruditapes2_lrc3972 14.98 14.98 -14.98 -1.557 -1.06E-05 -1.546 -1.779 0.075 0.677 1 beta 2b /// 0005515 // protein binding /// 0000166 // nucleotide binding /// 0007017 // microtubule-based process 41.88 652 302 712 41.88 41.88 26.9 652 335 "1,017" 26.9 26.9 ruditapes2_c1559 40.556 40.556 -40.556 -1.554 -2.87E-05 -1.543 -2.921 3.49E-03 0.065 1 ependymin related protein-1 precursor 113.828 752 "2,232" "2,232" 113.828 113.828 73.272 752 "3,195" "3,195" 73.272 73.272 ruditapes_lrc23736 90.338 90.338 -90.338 -1.548 -6.38E-05 -1.537 -4.342 1.42E-05 5.26E-04 0.461 cg5499-pa /// 0005811 // lipid particle /// 0005634 // nucleus /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0005700 // polytene chromosome /// 0000786 // nucleosome 255.223 829 39 "5,517" 255.223 255.223 164.885 829 82 "7,926" 164.885 164.885 ruditapes2_c3228 16.954 16.954 -16.954 -1.546 -1.20E-05 -1.535 -1.878 0.06 0.586 1 glutathione peroxidase 3 /// 0006749 // glutathione metabolic process /// 0005625 // soluble fraction /// 0005615 // extracellular space /// 0042744 // hydrogen peroxide catabolic process /// 0008430 // selenium binding /// 0008134 // transcription factor binding /// 0006982 // response to lipid hydroperoxide /// 0004602 // glutathione peroxidase activity /// 0051289 // protein homotetramerization /// 0043295 // glutathione binding 48.014 "1,131" 617 "1,416" 48.014 48.014 31.061 "1,131" 793 "2,037" 31.061 31.061 ruditapes2_c331 28.998 28.998 -28.998 -1.546 -2.05E-05 -1.536 -2.457 0.014 0.201 1 tgf beta-inducible nuclear protein 1 82.081 948 795 "2,029" 82.081 82.081 53.083 948 "1,202" "2,918" 53.083 53.083 ruditapes2_c4432 13.443 13.443 -13.443 -1.544 -9.50E-06 -1.534 -1.67 0.095 0.783 1 slc25a3-prov protein /// 0016020 // membrane 38.155 589 157 586 38.155 38.155 24.712 589 267 844 24.712 24.712 ruditapes2_lrc4116 35.825 35.825 -35.825 -1.54 -2.53E-05 -1.53 -2.718 6.57E-03 0.11 1 ribosomal protein s14e /// 0005811 // lipid particle /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 102.164 613 45 "1,633" 102.164 102.164 66.338 613 61 "2,358" 66.338 66.338 ruditapes2_c3457 34.403 34.403 -34.403 -1.539 -2.43E-05 -1.529 -2.662 7.77E-03 0.127 1 activating transcription factor 4 /// 0016563 // transcription activator activity /// 0050811 // GABA receptor binding /// 0045944 // positive regulation of transcription from RNA polymerase II promoter /// 0003704 // specific RNA polymerase II transcription factor activity /// 0003677 // DNA binding /// 0005667 // transcription factor complex /// 0005737 // cytoplasm /// 0008022 // protein C-terminus binding /// 0006094 // gluconeogenesis 98.19 "1,467" "1,109" "3,756" 98.19 98.19 63.787 "1,467" "1,666" "5,426" 63.787 63.787 ruditapes_c2884 49.836 49.836 -49.836 -1.534 -3.52E-05 -1.523 -3.191 1.42E-03 0.031 1 alpha tubulin /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0005874 // microtubule /// 0007018 // microtubule-based movement 143.197 590 222 "2,203" 143.197 143.197 93.361 590 477 "3,194" 93.361 93.361 ruditapes_c31191 "6,707.47" "6,707.47" "-6,707.47" -1.534 -4.74E-03 -1.524 -37.253 1.12E-303 1.83E-300 3.65E-299 nadh dehydrogenase subunit 4 /// 0005739 // mitochondrion /// 0016020 // membrane /// 0008137 // NADH dehydrogenase (ubiquinone) activity /// 0042773 // ATP synthesis coupled electron transport "19,257.57" 624 "313,339" "313,339" "19,257.57" "19,257.57" "12,550.10" 624 "454,098" "454,098" "12,550.10" "12,550.10" ruditapes_lrc35365 104.165 104.165 -104.165 -1.533 -7.36E-05 -1.523 -4.61 4.02E-06 1.69E-04 0.131 60s ribosomal protein l9 299.573 647 777 "5,054" 299.573 299.573 195.407 647 752 "7,331" 195.407 195.407 ruditapes2_c244 49.118 49.118 -49.118 -1.525 -3.47E-05 -1.515 -3.146 1.66E-03 0.035 1 connective tissue growth factor 142.676 640 "2,267" "2,381" 142.676 142.676 93.558 640 "3,233" "3,472" 93.558 93.558 ruditapes2_lrc2178 47.507 47.507 -47.507 -1.524 -3.35E-05 -1.514 -3.091 1.99E-03 0.041 1 actin /// 0030029 // actin filament-based process /// 0000910 // cytokinesis /// 0005488 // binding /// 0000003 // reproduction /// 0048513 // organ development /// 0009790 // embryonic development 138.184 814 258 "2,933" 138.184 138.184 90.678 814 398 "4,280" 90.678 90.678 ruditapes2_c101 20.165 20.165 -20.165 -1.516 -1.42E-05 -1.505 -2.001 0.045 0.48 1 high-mobility group box 3 /// 0007275 // multicellular organismal development 59.269 759 490 "1,173" 59.269 59.269 39.104 759 706 "1,721" 39.104 39.104 ruditapes2_c2172 15.347 15.347 -15.347 -1.513 -1.08E-05 -1.503 -1.742 0.081 0.712 1 hypothetical protein [Schistosoma mansoni] 45.239 540 637 637 45.239 45.239 29.893 540 936 936 29.893 29.893 ruditapes2_lrc5699 44.911 44.911 -44.911 -1.513 -3.17E-05 -1.503 -2.98 2.88E-03 0.056 1 ribosomal protein s5 /// 0006414 // translational elongation /// 0006413 // translational initiation /// 0003729 // mRNA binding /// 0006450 // regulation of translational fidelity /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 132.452 670 49 "2,314" 132.452 132.452 87.541 670 110 "3,401" 87.541 87.541 ruditapes2_c24 39.894 39.894 -39.894 -1.507 -2.82E-05 -1.497 -2.795 5.19E-03 0.09 1 tropomyosin 118.553 "2,497" 535 "7,719" 118.553 118.553 78.659 "2,497" 836 "11,389" 78.659 78.659 ruditapes_lrc32677 107.519 107.519 -107.519 -1.505 -7.59E-05 -1.495 -4.58 4.65E-06 1.94E-04 0.152 ribosomal protein s11 /// 0005840 // ribosome /// 0019843 // rRNA binding /// 0006412 // translation /// 0003735 // structural constituent of ribosome 320.553 530 120 "4,430" 320.553 320.553 213.034 530 129 "6,547" 213.034 213.034 ruditapes_lrc39605 65.031 65.031 -65.031 -1.498 -4.59E-05 -1.488 -3.542 3.98E-04 0.01 1 ribosomal protein s17 /// 0006414 // translational elongation /// 0034101 // erythrocyte homeostasis /// 0006413 // translational initiation /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 195.653 472 146 "2,408" 195.653 195.653 130.622 472 325 "3,575" 130.622 130.622 ruditapes_lrc36032 27.559 27.559 27.559 1.503 2.01E-05 1.513 2.391 0.017 0.23 1 nadh dehydrogenase subunit 1 54.832 719 651 "1,028" 54.832 54.832 82.391 719 "2,126" "3,435" 82.391 82.391 ruditapes2_c1331 20.35 20.35 20.35 1.503 1.49E-05 1.513 2.054 0.04 0.44 1 ribosomal protein l12e /// 0005811 // lipid particle /// 0030529 // ribonucleoprotein complex /// 0000022 // mitotic spindle elongation 40.492 394 3 416 40.492 40.492 60.842 394 12 "1,390" 60.842 60.842 ruditapes_lrc34958 16.845 16.845 16.845 1.509 1.23E-05 1.519 1.878 0.06 0.586 1 40s ribosomal protein s27 /// 0006414 // translational elongation /// 0008283 // cell proliferation /// 0005634 // nucleus /// 0005515 // protein binding /// 0003677 // DNA binding /// 0008270 // zinc ion binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 33.094 518 97 447 33.094 33.094 49.939 518 259 "1,500" 49.939 49.939 ruditapes_c226 240.448 240.448 240.448 1.545 1.75E-04 1.556 7.287 3.17E-13 3.22E-11 1.03E-08 ribosomal protein s2 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005654 // nucleoplasm /// 0003723 // RNA binding /// 0048604 // fibroblast growth factor 3 binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0048602 // fibroblast growth factor 1 binding 440.947 914 715 "10,509" 440.947 440.947 681.396 914 "2,404" "36,113" 681.396 681.396 ruditapes_c5403 23.957 23.957 23.957 1.547 1.75E-05 1.557 2.302 0.021 0.275 1 zgc:172187 protein /// 0032501 // multicellular organismal process /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process /// 0005634 // nucleus /// 0048522 // positive regulation of cellular process /// 0051439 // regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005737 // cytoplasm /// 0006464 // protein modification process 43.829 490 475 560 43.829 43.829 67.786 490 "1,628" "1,926" 67.786 67.786 ruditapes_lrc36809 13.53 13.53 13.53 1.558 9.86E-06 1.568 1.743 0.081 0.711 1 s9 ribosomal protein /// 0015935 // small ribosomal subunit /// 0019843 // rRNA binding /// 0006412 // translation /// 0003735 // structural constituent of ribosome 24.266 501 53 317 24.266 24.266 37.796 501 165 "1,098" 37.796 37.796 ruditapes_c93 35.373 35.373 35.373 1.583 2.58E-05 1.593 2.865 4.17E-03 0.075 1 wnt1-inducible-signaling pathway protein 1 precursor (wisp-1) (wnt-1-induced secreted protein) 60.716 "1,046" "1,656" "1,656" 60.716 60.716 96.088 "1,046" "5,828" "5,828" 96.088 96.088 ruditapes2_c245 55.884 55.884 55.884 1.593 4.07E-05 1.604 3.625 2.89E-04 7.88E-03 1 ribosomal protein s4 /// 0007275 // multicellular organismal development /// 0006414 // translational elongation /// 0008284 // positive regulation of cell proliferation /// 0045727 // positive regulation of translation /// 0019843 // rRNA binding /// 0005844 // polysome /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 94.264 797 295 "1,959" 94.264 94.264 150.148 797 "1,141" "6,939" 150.148 150.148 ruditapes_lrc33080 15.279 15.279 15.279 1.605 1.11E-05 1.616 1.91 0.056 0.559 1 tubulin alpha-1 chain "/// 0005524 // ATP binding /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0016021 // integral to membrane /// 0005874 // microtubule /// 0042626 // ATPase activity, coupled to transmembrane movement of substances /// 0007018 // microtubule-based movement" 25.26 750 290 494 25.26 25.26 40.539 750 773 "1,763" 40.539 40.539 ruditapes_lrc8537 11.04 11.04 11.04 1.62 8.04E-06 1.631 1.638 0.101 0.813 1 cytochrome oxidase subunit 1 17.818 551 59 256 17.818 17.818 28.858 551 144 922 28.858 28.858 ruditapes2_c462 "4,435.23" "4,435.23" "4,435.23" 1.622 3.23E-03 1.633 32.99 0 0 0 cytochrome oxidase subunit 1 /// 0009060 // aerobic respiration /// 0006810 // transport /// 0022900 // electron transport chain /// 0005507 // copper ion binding /// 0004129 // cytochrome-c oxidase activity /// 0020037 // heme binding /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane /// 0009055 // electron carrier activity "7,131.09" "1,728" "77,710" "321,313" "7,131.09" "7,131.09" "11,566.32" "1,728" "282,811" "1,158,929" "11,566.32" "11,566.32" ruditapes_lrc32583 59.307 59.307 59.307 1.634 4.32E-05 1.645 3.829 1.29E-04 3.87E-03 1 ribosomal protein s18 /// 0007275 // multicellular organismal development /// 0006414 // translational elongation /// 0051726 // regulation of cell cycle /// 0019843 // rRNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0006417 // regulation of translation 93.507 518 33 "1,263" 93.507 93.507 152.815 518 77 "4,590" 152.815 152.815 ruditapes2_lrc4262 39.641 39.641 39.641 1.638 2.89E-05 1.649 3.137 1.71E-03 0.036 1 ribosomal protein s8 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 62.129 779 138 "1,262" 62.129 62.129 101.77 779 554 "4,597" 101.77 101.77 ruditapes_lrc15460 172.241 172.241 172.241 1.662 1.25E-04 1.673 6.628 3.39E-11 2.85E-09 1.11E-06 elongation factor-1 alpha /// 0006414 // translational elongation /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0005737 // cytoplasm /// 0003746 // translation elongation factor activity 260.259 585 "3,932" "3,970" 260.259 260.259 432.5 585 "14,247" "14,671" 432.5 432.5 ruditapes_lrc35863 11.276 11.276 11.276 1.698 8.20E-06 1.709 1.729 0.084 0.726 1 ribosomal protein l13a /// 0015934 // large ribosomal subunit /// 0006412 // translation /// 0003735 // structural constituent of ribosome 16.157 667 67 281 16.157 16.157 27.433 667 169 "1,061" 27.433 27.433 ruditapes_lrc39310 24.841 24.841 24.841 1.719 1.81E-05 1.73 2.593 9.51E-03 0.149 1 atp:adp antiporter /// 0044464 // cell part 34.559 799 138 720 34.559 34.559 59.4 799 561 "2,752" 59.4 59.4 ruditapes2_c5679 11.471 11.471 11.471 1.726 8.34E-06 1.737 1.768 0.077 0.687 1 ribosomal protein s15 /// 0005840 // ribosome 15.809 507 25 209 15.809 15.809 27.28 507 75 802 27.28 27.28 ruditapes2_c416 9.46 9.46 9.46 1.782 6.87E-06 1.794 1.648 0.099 0.802 1 actin /// 0005524 // ATP binding /// 0005856 // cytoskeleton /// 0005515 // protein binding /// 0005737 // cytoplasm 12.105 "1,074" 26 339 12.105 12.105 21.565 "1,074" 248 "1,343" 21.565 21.565 ruditapes_lrc21103 61.732 61.732 61.732 1.783 4.48E-05 1.795 4.213 2.52E-05 8.84E-04 0.82 cytochrome oxidase subunit 1 78.867 478 428 983 78.867 78.867 140.6 478 "1,123" "3,897" 140.6 140.6 ruditapes2_lrc3101 95.45 95.45 95.45 1.802 6.93E-05 1.814 5.283 1.27E-07 6.72E-06 4.15E-03 guanine nucleotide binding protein (g protein) beta polypeptide 2-like 1 /// 0005080 // protein kinase C binding /// 0007205 // activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway /// 0019903 // protein phosphatase binding /// 0005886 // plasma membrane /// 0043025 // cell soma /// 0005737 // cytoplasm /// 0005102 // receptor binding /// 0016301 // kinase activity /// 0004872 // receptor activity 119.08 "1,133" 642 "3,518" 119.08 119.08 214.529 "1,133" "2,537" "14,094" 214.529 214.529 ruditapes2_lrc3558 238.623 238.623 238.623 1.842 1.73E-04 1.855 8.498 0 0 0 ferritin /// 0046914 // transition metal ion binding 283.324 539 544 "3,982" 283.324 283.324 521.948 539 "1,575" "16,313" 521.948 521.948 ruditapes2_lrc5557 22.634 22.634 22.634 1.867 1.64E-05 1.879 2.643 8.23E-03 0.134 1 ribosomal protein l35a /// 0006414 // translational elongation /// 0005515 // protein binding /// 0005840 // ribosome /// 0006364 // rRNA processing /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome /// 0000049 // tRNA binding /// 0042273 // ribosomal large subunit biogenesis 26.113 398 19 271 26.113 26.113 48.747 398 91 "1,125" 48.747 48.747 ruditapes2_lrc5010 42.131 42.131 42.131 1.906 3.06E-05 1.919 3.66 2.52E-04 7.01E-03 1 ribosomal protein s16 /// 0005811 // lipid particle /// 0042254 // ribosome biogenesis /// 0005488 // binding /// 0015935 // small ribosomal subunit /// 0000022 // mitotic spindle elongation /// 0006412 // translation /// 0005829 // cytosol 46.494 518 1 628 46.494 46.494 88.626 518 3 "2,662" 88.626 88.626 ruditapes_c19045 70.858 70.858 70.858 1.916 5.14E-05 1.929 4.764 1.90E-06 8.49E-05 0.062 actin /// 0005488 // binding /// 0005625 // soluble fraction /// 0005829 // cytosol /// 0030863 // cortical cytoskeleton 77.372 457 904 922 77.372 77.372 148.23 457 "3,695" "3,928" 148.23 148.23 ruditapes_lrc38869 8.742 8.742 8.742 1.927 6.34E-06 1.94 1.68 0.093 0.774 1 beta 2b /// 0005515 // protein binding 9.428 541 33 133 9.428 9.428 18.17 541 181 570 18.17 18.17 ruditapes_lrc38746 12.231 12.231 12.231 1.957 8.87E-06 1.97 2.008 0.045 0.476 1 tubulin alpha-1 chain /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0005874 // microtubule /// 0007018 // microtubule-based movement 12.784 333 85 111 12.784 12.784 25.014 333 269 483 25.014 25.014 ruditapes_lrc33024 15.893 15.893 15.893 1.98 1.15E-05 1.993 2.307 0.021 0.273 1 ribosomal protein l17 /// 0006414 // translational elongation /// 0015934 // large ribosomal subunit /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 16.223 617 27 261 16.223 16.223 32.116 617 89 "1,149" 32.116 32.116 ruditapes_lrc32728 12.672 12.672 12.672 2.011 9.19E-06 2.024 2.081 0.037 0.421 1 laminin receptor 1 /// 0034961 // cellular biopolymer biosynthetic process /// 0005624 // membrane fraction /// 0043236 // laminin binding /// 0044238 // primary metabolic process /// 0005840 // ribosome /// 0010467 // gene expression 12.54 578 25 189 12.54 12.54 25.212 578 90 845 25.212 25.212 ruditapes_lrc33287 17.301 17.301 17.301 2.036 1.25E-05 2.05 2.451 0.014 0.203 1 ubiquitin a-52 residue ribosomal protein fusion product 1 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0006464 // protein modification process 16.7 457 5 199 16.7 16.7 34.001 457 31 901 34.001 34.001 ruditapes2_lrc5734 139.701 139.701 139.701 2.099 1.01E-04 2.113 7.097 1.27E-12 1.20E-10 4.14E-08 ribosomal protein s24 /// 0005811 // lipid particle /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 127.138 495 171 "1,641" 127.138 127.138 266.839 495 360 "7,659" 266.839 266.839 ruditapes2_lrc5631 19.212 19.212 19.212 2.114 1.39E-05 2.128 2.643 8.21E-03 0.134 1 40s ribosomal protein s10 /// 0005840 // ribosome 17.248 587 27 264 17.248 17.248 36.46 587 138 "1,241" 36.46 36.46 ruditapes2_lrc4151 8.563 8.563 8.563 2.219 6.20E-06 2.234 1.814 0.07 0.643 1 basic transcription factor 3-like 4 7.027 906 0 166 7.027 7.027 15.59 906 13 819 15.59 15.59 ruditapes_c25365 38.233 38.233 38.233 2.239 2.77E-05 2.254 3.853 1.17E-04 3.55E-03 1 tubulin alpha-1 chain /// 0005198 // structural molecule activity /// 0051258 // protein polymerization /// 0005525 // GTP binding /// 0003924 // GTPase activity /// 0043234 // protein complex /// 0005874 // microtubule /// 0007018 // microtubule-based movement 30.861 466 375 375 30.861 30.861 69.094 466 "1,867" "1,867" 69.094 69.094 ruditapes_c6314 "1,729.78" "1,729.78" "1,729.78" 2.265 1.25E-03 2.281 26.106 0 0 0 cytochrome b /// 0006810 // transport /// 0005739 // mitochondrion /// 0016491 // oxidoreductase activity /// 0016021 // integral to membrane /// 0009055 // electron carrier activity /// 0005506 // iron ion binding /// 0022904 // respiratory electron transport chain "1,367.12" 574 "11,988" "20,462" "1,367.12" "1,367.12" "3,096.90" 574 "64,560" "103,076" "3,096.90" "3,096.90" ruditapes2_lrc3864 10.963 10.963 10.963 2.266 7.94E-06 2.282 2.077 0.038 0.423 1 tropomyosin 8.657 886 80 200 8.657 8.657 19.62 886 283 "1,008" 19.62 19.62 ruditapes_lrc35570 10.171 10.171 10.171 2.277 7.36E-06 2.293 2.006 0.045 0.477 1 laminin receptor 1 /// 0005624 // membrane fraction /// 0043236 // laminin binding /// 0015935 // small ribosomal subunit /// 0006412 // translation /// 0003735 // structural constituent of ribosome /// 0004872 // receptor activity 7.963 602 17 125 7.963 7.963 18.134 602 82 633 18.134 18.134 ruditapes2_lrc4546 9.451 9.451 9.451 2.297 6.84E-06 2.312 1.942 0.052 0.53 1 histone /// 0002119 // nematode larval development /// 0040010 // positive regulation of growth rate /// 0001740 // Barr body /// 0006334 // nucleosome assembly /// 0003677 // DNA binding /// 0010171 // body morphogenesis /// 0007155 // cell adhesion /// 0008360 // regulation of cell shape /// 0009792 // embryonic development ending in birth or egg hatching /// 0000786 // nucleosome 7.289 784 4 149 7.289 7.289 16.74 784 43 761 16.74 16.74 ruditapes2_c215 8.709 8.709 8.709 2.347 6.30E-06 2.363 1.885 0.059 0.58 1 60s acidic ribosomal protein p2 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0003735 // structural constituent of ribosome 6.466 433 4 73 6.466 6.466 15.175 433 7 381 15.175 15.175 ruditapes_lrc35449 24.387 24.387 24.387 2.377 1.77E-05 2.393 3.175 1.50E-03 0.032 1 ribosomal protein l8 /// 0006414 // translational elongation /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0003735 // structural constituent of ribosome 17.708 719 31 332 17.708 17.708 42.095 719 86 "1,755" 42.095 42.095 ruditapes_lrc35096 16.421 16.421 16.421 2.426 1.19E-05 2.443 2.632 8.49E-03 0.136 1 apextrin 11.512 "1,086" 44 326 11.512 11.512 27.933 "1,086" 317 "1,759" 27.933 27.933 ruditapes_c24684 6.506 6.506 6.506 2.444 4.71E-06 2.46 1.662 0.096 0.788 1 protein 4.507 451 53 53 4.507 4.507 11.013 451 287 288 11.013 11.013 ruditapes2_c5684 21.893 21.893 21.893 2.448 1.58E-05 2.465 3.052 2.27E-03 0.046 1 60s acidic ribosomal protein p1 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0003735 // structural constituent of ribosome 15.12 383 8 151 15.12 15.12 37.013 383 20 822 37.013 37.013 ruditapes2_c4794 212.514 212.514 212.514 2.589 1.54E-04 2.607 9.761 0 0 0 ribosomal protein s12 /// 0006414 // translational elongation /// 0005739 // mitochondrion /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 133.733 466 148 "1,625" 133.733 133.733 346.247 466 619 "9,356" 346.247 346.247 ruditapes_c9171 9.856 9.856 9.856 2.603 7.13E-06 2.621 2.107 0.035 0.403 1 cathepsin b precursor /// 0006508 // proteolysis /// 0004197 // cysteine-type endopeptidase activity 6.147 680 109 109 6.147 6.147 16.003 680 631 631 16.003 16.003 ruditapes_lrc34660 29.903 29.903 29.903 2.621 2.16E-05 2.639 3.681 2.32E-04 6.49E-03 1 60s ribosomal protein l13a /// 0015934 // large ribosomal subunit /// 0006412 // translation /// 0003735 // structural constituent of ribosome 18.442 549 117 264 18.442 18.442 48.345 549 528 "1,539" 48.345 48.345 ruditapes_lrc27510 13.196 13.196 13.196 2.688 9.54E-06 2.707 2.472 0.013 0.193 1 cytochrome oxidase subunit 1 /// 0046914 // transition metal ion binding /// 0016020 // membrane /// 0008152 // metabolic process 7.815 687 53 140 7.815 7.815 21.011 687 230 837 21.011 21.011 ruditapes_lrc34108 5.697 5.697 5.697 2.716 4.12E-06 2.735 1.631 0.103 0.821 1 beta isoform cra_a 3.319 855 0 74 3.319 3.319 9.016 855 6 447 9.016 9.016 ruditapes_lrc32780 8.242 8.242 8.242 2.765 5.96E-06 2.784 1.977 0.048 0.5 1 h+ transporting f1 atp synthase epsilon subunit "/// 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism" 4.67 386 0 47 4.67 4.67 12.912 386 13 289 12.912 12.912 ruditapes_lrc36885 10.82 10.82 10.82 2.855 7.82E-06 2.874 2.294 0.022 0.28 1 ribosomal protein s5 /// 0006414 // translational elongation /// 0006413 // translational initiation /// 0003729 // mRNA binding /// 0006450 // regulation of translational fidelity /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 5.832 697 0 106 5.832 5.832 16.652 697 18 673 16.652 16.652 ruditapes_lrc34349 10.884 10.884 10.884 3.051 7.86E-06 3.072 2.359 0.018 0.246 1 ribosomal protein l14 /// 0030529 // ribonucleoprotein complex 5.305 506 0 70 5.305 5.305 16.189 506 8 475 16.189 16.189 ruditapes_c1671 10.837 10.837 10.837 3.185 7.83E-06 3.207 2.39 0.017 0.23 1 translationally controlled tumor protein /// 0007275 // multicellular organismal development /// 0040007 // growth /// 0005488 // binding 4.959 464 0 60 4.959 4.959 15.796 464 13 425 15.796 15.796 ruditapes_lrc34207 16.558 16.558 16.558 3.228 1.20E-05 3.25 2.968 3.00E-03 0.058 1 ribosomal protein l8 /// 0006414 // translational elongation /// 0022625 // cytosolic large ribosomal subunit /// 0019843 // rRNA binding /// 0003735 // structural constituent of ribosome 7.431 578 4 112 7.431 7.431 23.989 578 47 804 23.989 23.989 ruditapes_lrc33543 6.344 6.344 6.344 3.238 4.58E-06 3.26 1.839 0.066 0.62 1 atp:adp antiporter /// 0006839 // mitochondrial transport /// 0005488 // binding /// 0015865 // purine nucleotide transport /// 0005471 // ATP:ADP antiporter activity /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane /// 0009536 // plastid 2.835 744 0 55 2.835 2.835 9.179 744 3 396 9.179 9.179 ruditapes_lrc35066 5.838 5.838 5.838 3.245 4.22E-06 3.267 1.765 0.078 0.689 1 GF24496 [Drosophila ananassae] 2.6 885 6 60 2.6 2.6 8.438 885 53 433 8.438 8.438 ruditapes2_c1075 17.02 17.02 17.02 3.277 1.23E-05 3.299 3.024 2.50E-03 0.05 1 b-cell translocation gene 1 7.476 949 28 185 7.476 7.476 24.497 949 209 "1,348" 24.497 24.497 ruditapes_lrc38572 7.815 7.815 7.815 3.373 5.64E-06 3.396 2.068 0.039 0.43 1 ribosomal protein s18 /// 0007275 // multicellular organismal development /// 0006414 // translational elongation /// 0051726 // regulation of cell cycle /// 0019843 // rRNA binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0006417 // regulation of translation 3.294 489 0 42 3.294 3.294 11.109 489 3 315 11.109 11.109 ruditapes2_c19 6.825 6.825 6.825 3.451 4.93E-06 3.475 1.947 0.052 0.525 1 40s ribosomal protein s2 /// 0006414 // translational elongation /// 0005730 // nucleolus /// 0005654 // nucleoplasm /// 0003723 // RNA binding /// 0048604 // fibroblast growth factor 3 binding /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit /// 0048602 // fibroblast growth factor 1 binding 2.784 551 2 40 2.784 2.784 9.609 551 21 307 9.609 9.609 ruditapes_lrc35347 8.983 8.983 8.983 3.554 6.49E-06 3.578 2.254 0.024 0.304 1 ribosomal protein s19 /// 0030529 // ribonucleoprotein complex 3.518 447 1 41 3.518 3.518 12.5 447 10 324 12.5 12.5 ruditapes_lrc32456 13.727 13.727 13.727 3.566 9.91E-06 3.59 2.789 5.29E-03 0.092 1 ribosomal protein l9 /// 0030529 // ribonucleoprotein complex 5.35 810 0 113 5.35 5.35 19.077 810 2 896 19.077 19.077 ruditapes_lrc31623 8.516 8.516 8.516 3.897 6.15E-06 3.924 2.253 0.024 0.305 1 cytochrome oxidase subunit 1 /// 0044237 // cellular metabolic process /// 0046872 // metal ion binding /// 0003824 // catalytic activity /// 0044464 // cell part 2.939 548 22 42 2.939 2.939 11.455 548 165 364 11.455 11.455 ruditapes_lrc28453 33.747 33.747 33.747 4.007 2.44E-05 4.034 4.518 6.24E-06 2.52E-04 0.203 ferritin /// 0005488 // binding 11.223 762 138 223 11.223 11.223 44.97 762 939 "1,987" 44.97 44.97 ruditapes2_lrc5592 5.156 5.156 5.156 4.025 3.72E-06 4.052 1.768 0.077 0.687 1 kda midgut partial 1.704 450 0 20 1.704 1.704 6.86 450 7 179 6.86 6.86 ruditapes_lrc34458 22.261 22.261 22.261 4.336 1.61E-05 4.365 3.743 1.82E-04 5.27E-03 1 basic transcription factor 3-like 4 6.673 931 0 162 6.673 6.673 28.934 931 25 "1,562" 28.934 28.934 ruditapes_lrc33519 7.331 7.331 7.331 4.422 5.29E-06 4.452 2.158 0.031 0.367 1 ribosomal protein s24 /// 0030529 // ribonucleoprotein complex 2.142 537 1 30 2.142 2.142 9.474 537 7 295 9.474 9.474 ruditapes_lrc33766 21.549 21.549 21.549 4.474 1.56E-05 4.504 3.71 2.08E-04 5.91E-03 1 ribosomal protein l27 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0005829 // cytosol /// 0003735 // structural constituent of ribosome 6.204 476 0 77 6.204 6.204 27.753 476 17 766 27.753 27.753 ruditapes2_c4916 11.968 11.968 11.968 4.614 8.64E-06 4.645 2.784 5.37E-03 0.093 1 large subunit ribosomal protein 30 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 3.312 579 0 50 3.312 3.312 15.28 579 12 513 15.28 15.28 ruditapes2_lrc4084 6.307 6.307 6.307 4.633 4.55E-06 4.665 2.023 0.043 0.463 1 galactoside- 8 /// 0005634 // nucleus /// 0005515 // protein binding /// 0030198 // extracellular matrix organization /// 0001501 // skeletal system development /// 0005737 // cytoplasm /// 0005578 // proteinaceous extracellular matrix 1.736 729 0 33 1.736 1.736 8.043 729 34 340 8.043 8.043 ruditapes2_c356 5.678 5.678 5.678 4.663 4.10E-06 4.694 1.922 0.055 0.547 1 ppig protein /// 0005634 // nucleus 1.55 470 19 19 1.55 1.55 7.229 470 194 197 7.229 7.229 ruditapes_lrc16378 34.307 34.307 34.307 4.713 2.48E-05 4.745 4.736 2.18E-06 9.54E-05 0.071 ubiquitin family protein /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle /// 0005654 // nucleoplasm /// 0030528 // transcription regulator activity /// 0016567 // protein ubiquitination /// 0005829 // cytosol /// 0045941 // positive regulation of transcription 9.239 440 52 106 9.239 9.239 43.546 440 252 "1,111" 43.546 43.546 ruditapes2_c10 49.936 49.936 49.936 4.743 3.60E-05 4.775 5.722 1.05E-08 6.80E-07 3.44E-04 ribosomal protein s24 /// 0005840 // ribosome 13.342 526 12 183 13.342 13.342 63.278 526 67 "1,930" 63.278 63.278 ruditapes_lrc32178 13.197 13.197 13.197 4.874 9.52E-06 4.907 2.959 3.09E-03 0.059 1 atp synthase beta "/// 0005524 // ATP binding /// 0005811 // lipid particle /// 0000275 // mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism /// 0015986 // ATP synthesis coupled proton transport /// 0046961 // proton-transporting ATPase activity, rotational mechanism /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism" 3.406 698 3 62 3.406 3.406 16.603 698 77 672 16.603 16.603 ruditapes2_c1383 12.476 12.476 12.476 4.954 9.00E-06 4.988 2.887 3.89E-03 0.072 1 actin /// 0005524 // ATP binding /// 0005856 // cytoskeleton /// 0005515 // protein binding /// 0005737 // cytoplasm 3.155 705 4 58 3.155 3.155 15.631 705 57 639 15.631 15.631 ruditapes_lrc33999 28.762 28.762 28.762 4.996 2.08E-05 5.03 4.39 1.13E-05 4.31E-04 0.369 40s ribosomal protein s10 /// 0005840 // ribosome 7.198 634 28 119 7.198 7.198 35.96 634 216 "1,322" 35.96 35.96 ruditapes2_c3418 5.888 5.888 5.888 5.272 4.25E-06 5.308 2.008 0.045 0.476 1 atp:adp antiporter /// 0006810 // transport /// 0005215 // transporter activity /// 0005488 // binding /// 0016021 // integral to membrane /// 0005743 // mitochondrial inner membrane 1.378 807 0 29 1.378 1.378 7.266 807 4 340 7.266 7.266 ruditapes_s38966 4.795 4.795 4.795 5.576 3.46E-06 5.614 1.831 0.067 0.626 1 elongation factor 1-beta /// 0006414 // translational elongation /// 0005853 // eukaryotic translation elongation factor 1 complex /// 0003746 // translation elongation factor activity 1.048 366 0 10 1.048 1.048 5.843 366 15 124 5.843 5.843 ruditapes_s36301 4.8 4.8 4.8 5.808 3.46E-06 5.848 1.846 0.065 0.614 1 ribosomal protein s19e /// 0030529 // ribonucleoprotein complex 0.998 461 0 12 0.998 0.998 5.798 461 12 155 5.798 5.798 ruditapes2_c3321 9.39 9.39 9.39 5.958 6.77E-06 5.999 2.593 9.52E-03 0.149 1 AF339450_1hillarin [Hirudo medicinalis] 1.894 "1,134" 4 56 1.894 1.894 11.284 "1,134" 39 742 11.284 11.284 ruditapes_lrc6892 4.01 4.01 4.01 5.974 2.89E-06 6.015 1.695 0.09 0.759 1 cytochrome c oxidase subunit viic 0.806 666 0 14 0.806 0.806 4.816 666 6 186 4.816 4.816 ruditapes_c703 "16,596.14" "16,596.14" "16,596.14" 6.474 0.012 6.518 111.186 0 0 0 structural polyprotein "3,031.72" 872 "68,934" "68,934" "3,031.72" "3,031.72" "19,627.86" 872 "992,447" "992,447" "19,627.86" "19,627.86" ruditapes2_lrc4303 10.47 10.47 10.47 6.901 7.55E-06 6.948 2.802 5.08E-03 0.089 1 mitochondrial cytochrome c oxidase subunit 6b /// 0005751 // mitochondrial respiratory chain complex IV 1.774 562 2 26 1.774 1.774 12.244 562 101 399 12.244 12.244 ruditapes_lrc32372 3.499 3.499 3.499 7.78 2.52E-06 7.832 1.647 0.1 0.804 1 galactoside- 3 /// 0005634 // nucleus /// 0005488 // binding /// 0005737 // cytoplasm 0.516 743 0 10 0.516 0.516 4.015 743 31 173 4.015 4.015 ruditapes2_lrc5155 19.813 19.813 19.813 8.056 1.43E-05 8.111 3.936 8.29E-05 2.60E-03 1 ribosomal protein l14 /// 0030529 // ribonucleoprotein complex 2.808 478 0 35 2.808 2.808 22.622 478 17 627 22.622 22.622 ruditapes2_c11 6.151 6.151 6.151 8.26 4.43E-06 8.316 2.2 0.028 0.339 1 ubiquitin-conjugating enzyme e2d 3 (ubc4 5 yeast) isoform cra_a /// 0040007 // growth /// 0002119 // nematode larval development /// 0030509 // BMP signaling pathway /// 0051246 // regulation of protein metabolic process /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process /// 0031625 // ubiquitin protein ligase binding /// 0051276 // chromosome organization /// 0048477 // oogenesis /// 0008340 // determination of adult lifespan /// 0007140 // male meiosis /// 0040011 // locomotion /// 0016567 // protein ubiquitination /// 0040035 // hermaphrodite genitalia development /// 0007286 // spermatid development /// 0045676 // regulation of R7 cell differentiation /// 0004842 // ubiquitin-protein ligase activity /// 0007067 // mitosis /// 0009792 // embryonic development ending in birth or egg hatching 0.847 860 1 19 0.847 0.847 6.999 860 30 349 6.999 6.999 ruditapes_lrc33015 8.107 8.107 8.107 8.619 5.84E-06 8.678 2.538 0.011 0.169 1 ribosomal protein l8 /// 0005840 // ribosome /// 0006412 // translation /// 0003735 // structural constituent of ribosome 1.064 865 0 24 1.064 1.064 9.171 865 22 460 9.171 9.171 ruditapes_lrc34048 22.117 22.117 22.117 8.896 1.59E-05 8.956 4.207 2.58E-05 9.04E-04 0.843 mitochondrial atp synthase lipid binding protein precursor "/// 0015992 // proton transport /// 0015078 // hydrogen ion transmembrane transporter activity /// 0045263 // proton-transporting ATP synthase complex, coupling factor F(o)" 2.801 753 0 55 2.801 2.801 24.918 753 38 "1,088" 24.918 24.918 ruditapes_c3889 3.982 3.982 3.982 9.547 2.87E-06 9.612 1.799 0.072 0.658 1 lethal neo18 0.466 "1,070" 0 13 0.466 0.466 4.448 "1,070" 33 276 4.448 4.448 ruditapes2_c5501 8.543 8.543 8.543 9.607 6.16E-06 9.672 2.637 8.37E-03 0.135 1 60s acidic ribosomal protein p1 /// 0006414 // translational elongation /// 0005840 // ribosome /// 0003735 // structural constituent of ribosome 0.993 425 0 11 0.993 0.993 9.536 425 7 235 9.536 9.536 ruditapes_c3253 4.925 4.925 4.925 9.743 3.55E-06 9.809 2.005 0.045 0.477 1 nadh dehydrogenase 1 beta 19kda 0.563 817 0 12 0.563 0.563 5.488 817 24 260 5.488 5.488 ruditapes_lrc34668 71.693 71.693 71.693 9.789 5.17E-05 9.856 7.653 1.95E-14 2.17E-12 6.37E-10 basic transcription factor 3-like 4 8.157 630 10 134 8.157 8.157 79.851 630 122 "2,917" 79.851 79.851 ruditapes_c36135 5.429 5.429 5.429 11.617 3.91E-06 11.696 2.14 0.032 0.38 1 a chain structural consequences of accommodation of four non- cognate amino-acid residues in the s1 pocket of bovine trypsin and chymotrypsin /// 0016787 // hydrolase activity 0.511 450 4 6 0.511 0.511 5.94 450 94 155 5.94 5.94 ruditapes_lrc31415 2.683 2.683 2.683 ? 1.93E-06 ? 1.638 0.101 0.813 1 ribosomal protein s24 /// 0006414 // translational elongation /// 0005634 // nucleus /// 0034101 // erythrocyte homeostasis /// 0005488 // binding /// 0042274 // ribosomal small subunit biogenesis /// 0006364 // rRNA processing /// 0003735 // structural constituent of ribosome /// 0022627 // cytosolic small ribosomal subunit 0 527 0 0 0 0 2.683 527 7 82 2.683 2.683